Effects of carbon dioxide arterial infusion on hepatic biochemistry and histology in a rabbit model

• Published in: Investigative radiology Vol. 30; no. 3; p. 192
• Main Authors: Mladinich, C R, Hawkins, Jr, I F, Heaton-Jones, T G, Shiroma, J T, Weingarten, K, Kiehl, A, Mays, M B, Kublis, P
• Format: Journal Article
• Language: English
• Published: United States 01.03.1995
• Subjects: Analysis of Variance; Animals; Carbon Dioxide - administration & dosage; Carbon Dioxide - pharmacology; Carbon Dioxide - toxicity; Contrast Media - administration & dosage; Contrast Media - pharmacology; Contrast Media - toxicity; Female; Infusions, Intra-Arterial; Liver - drug effects; Liver - metabolism; Liver - pathology; Male; Rabbits; Time Factors

The objective of this study was to determine the effect of carbon dioxide (CO2) infusion on hepatic biochemistry and histology in a rabbit model. The study population consisted of 24 anesthetized rabbits that received hepatic infusion of either CO2 or saline (control) at doses of 10 mL/kg, comparabl...