The Fatty Acid Composition of Maternal Diet Affects the Response to Excitotoxic Neural Injury in Neonatal Rat Pups

• Published in: Brain research bulletin Vol. 45; no. 6; pp. 637 - 640
• Main Authors: Valencia, Pablo, Carver, Jane D, Wyble, Lance E, Benford, Valerie J, Gilbert-Barness, Enid, Wiener, Doris A, Phelps, Christopher
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.04.1998; Elsevier Science
• Subjects: Animals; Animals, Newborn; Arachidonic acid; Atrophy; Biological and medical sciences; Brain - drug effects; Brain - pathology; Cerebral edema; Corn Oil; Dietary Fats; Excitatory Amino Acid Agonists - toxicity; Fatty Acids - analysis; Feeding. Feeding behavior; Female; Fish oil; Fish Oils; Fundamental and applied biological sciences. Psychology; Lactation; Milk - chemistry; N-Methylaspartate - toxicity; Neurons - drug effects; Neurons - pathology; Neurotoxins - toxicity; Nutrition; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Nutrition; Cerebral edema; Arachidonic acid; Fish oil; Rat; Toxicity; Arachidonic acid derivatives; Rodentia; Fatty acids; Prenatal; Vertebrata; Mammalia; Postnatal; Diet; Newborn animal; Excitatory aminoacid

Fatty acids and their derivatives play a role in the response to neural injury. The effects of prenatal and postnatal dietary fatty acid composition on excitotoxic neural injury were investigated in neonatal rat pups. Dams were fed during gestation and lactation a diet whose fat source was either co...