Oxidative metabolism of hexobarbital in human liver: relationship to polymorphic S-mephenytoin 4-hydroxylation - Knodell, R G; Dubey, R K; Wilkinson, G R; Guengerich, F P (The Journal of pharmacology and experimental therapeutics, 1988)
Keywords: Biological and medical sciences; Cytochrome P-450 Enzyme System - physiology; Hexobarbital - metabolism; Humans; Hydantoins - metabolism; Hydroxylation; Hypnotics. Sedatives; In Vitro Techniques; Liver - metabolism; Male; Medical sciences; Mephenytoin - metabolism; Neuropharmacology; Oxidation-Reduction; Pharmacology. Drug treatments; Polymorphism, Genetic; Psychology. Psychoanalysis. Psychiatry; Psychopharmacology; Human; Hexobarbital; Hemoprotein; Hydroxylation; Isozyme; Cytochrome P450; Liver; Hypnotic; Microsome; Metabolism; In vitro; In vivo; Barbituric