Regional gray matter-dedicated SUVR with 3D-MRI detects positive amyloid deposits in equivocal amyloid PET images

• Published in: Annals of nuclear medicine Vol. 34; no. 11; pp. 856 - 863
• Main Authors: Ishii, Kazunari, Yamada, Takahiro, Hanaoka, Kohei, Kaida, Hayato, Miyazaki, Koichi, Ueda, Masami, Hanada, Kazushi, Saigoh, Kazumasa, Sauerbeck, Julia, Rominger, Axel, Bartenstein, Peter, Kimura, Yuichi
• Format: Journal Article
• Language: English
• Published: Singapore Springer Singapore 01.11.2020; Springer Nature B.V
• Subjects: Alzheimer's disease; Deposits; Imaging; Inspection; Magnetic resonance imaging; Measurement methods; Medical imaging; Medicine; Medicine & Public Health; Nuclear Medicine; Original Article; Positron emission; Positron emission tomography; Radiology; Regional development; Sensitivity; Substantia alba; Substantia grisea; Tomography; C-PiB PET; Amyloid; Alzheimer’s disease; Equivocal accumulation; MRI

Purpose It is usually easy to judge whether amyloid PET images should be interpreted as positive or negative for amyloid deposits by visual inspection or quantitative measurement standard uptake value ratio (SUVR), but the findings are equivocal in some cases. As conventional mean cortical SUVR (mcS...