Glycyrol targets Pneumolysin (PLY) oligomerization to reduce Streptococcus pneumoniae toxicity

• Published in: Frontiers in pharmacology Vol. 15; p. 1478135
• Main Authors: Li, Yudi, Wu, Hongji, Hu, Yibo, Meng, Haoji, Xu, Yan
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 03.12.2024
• Subjects: glycyrol; Pharmacology; PLY; Streptococcus pneumoniae; TCM; toxicity; toxicity; PLY; glycyrol; Streptococcus pneumoniae; TCM

Exploring the potential of glycyrol to reduce the invasiveness of ( ). Cell experiments were performed using A549 alveolar epithelial cells and D39. Glycyrol was added to A549 cells mixed with or without Pneumolysin (PLY) to detect the effect of Glycyrol on PLY toxicity. Glycyrol was used to detect...