Neuroplasticity-Based Auditory Training Via Laptop Computer Improves Cognition in Young Individuals With Recent Onset Schizophrenia

• Published in: Schizophrenia bulletin Vol. 41; no. 1; pp. 250 - 258
• Main Authors: Fisher, M., Loewy, R., Carter, C., Lee, A., Ragland, J. D., Niendam, T., Schlosser, D., Pham, L., Miskovich, T., Vinogradov, S.
• Format: Journal Article
• Language: English
• Published: United States Oxford University Press 01.01.2015
• Subjects: Adolescent; Adult; Antipsychotic Agents - therapeutic use; Auditory Perception; Cognition Disorders - etiology; Cognition Disorders - psychology; Cognition Disorders - therapy; Cognitive Therapy - methods; Combined Modality Therapy; Double-Blind Method; Female; Humans; Male; Memory; Neuronal Plasticity; Problem Solving; Regular; Schizophrenia - complications; Schizophrenia - therapy; Schizophrenic Psychology; Therapy, Computer-Assisted - methods; Treatment Outcome; Verbal Learning; Young Adult; early psychosis; cognitive remediation; motivation; cognitive training; first-episode schizophrenia

Cognitive deficits that characterize schizophrenia are present in the prodrome, worsen with illness onset, and predict functional outcome. Cognitive dysfunction is thus a critical target for early intervention in young individuals with recent onset schizophrenia. This 2-site double-blind randomized...