Evaluation of premalignant and malignant lesions by fluorescent light (VELscope)
The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope). A total of 748 patients were evaluated through clinical and fluorescent light analysis of the entire oral cavity. Any lesion that was detected underwent a surgical excis...
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Published in | Journal of International Society of Preventive & Community Dentistry Vol. 5; no. 3; pp. 248 - 254 |
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Main Authors | , |
Format | Journal Article |
Language | English |
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India
Medknow Publications & Media Pvt. Ltd
01.05.2015
Medknow Publications & Media Pvt Ltd |
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Abstract | The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope).
A total of 748 patients were evaluated through clinical and fluorescent light analysis of the entire oral cavity. Any lesion that was detected underwent a surgical excision biopsy as the golden standard for the detection of the lesion's histology; then a comparison was made between the results to assure the efficacy of the fluorescent light analysis outcome.
About 9.4% of the lesions detected were abnormal lesions and 83.09% had loss of fluorescent light effect. Based on the use of surgical biopsy, the machine had a sensitivity of 74.1% and a specificity of 96.3%. According to the statistical analysis, the P value was much lower than 0.05, so we can conclude that at 95% confidence level, there was significant agreement between VELscope results and biopsy results. Kappa coefficient value was approximately 0.5, which means that the strength of the agreement was medium.
VELscope can be used as a clinical diagnostic aid in the detection of premalignant and malignant lesions of the oral cavity. In addition, it helps in the detection of the borders in both surgical biopsy and surgical excision. |
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AbstractList | The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope).
A total of 748 patients were evaluated through clinical and fluorescent light analysis of the entire oral cavity. Any lesion that was detected underwent a surgical excision biopsy as the golden standard for the detection of the lesion's histology; then a comparison was made between the results to assure the efficacy of the fluorescent light analysis outcome.
About 9.4% of the lesions detected were abnormal lesions and 83.09% had loss of fluorescent light effect. Based on the use of surgical biopsy, the machine had a sensitivity of 74.1% and a specificity of 96.3%. According to the statistical analysis, the P value was much lower than 0.05, so we can conclude that at 95% confidence level, there was significant agreement between VELscope results and biopsy results. Kappa coefficient value was approximately 0.5, which means that the strength of the agreement was medium.
VELscope can be used as a clinical diagnostic aid in the detection of premalignant and malignant lesions of the oral cavity. In addition, it helps in the detection of the borders in both surgical biopsy and surgical excision. Aim: The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope). Materials and Methods: A total of 748 patients were evaluated through clinical and fluorescent light analysis of the entire oral cavity. Any lesion that was detected underwent a surgical excision biopsy as the golden standard for the detection of the lesion's histology; then a comparison was made between the results to assure the efficacy of the fluorescent light analysis outcome. Results: About 9.4% of the lesions detected were abnormal lesions and 83.09% had loss of fluorescent light effect. Based on the use of surgical biopsy, the machine had a sensitivity of 74.1% and a specificity of 96.3%. According to the statistical analysis, the P value was much lower than 0.05, so we can conclude that at 95% confidence level, there was significant agreement between VELscope results and biopsy results. Kappa coefficient value was approximately 0.5, which means that the strength of the agreement was medium. Conclusion: VELscope can be used as a clinical diagnostic aid in the detection of premalignant and malignant lesions of the oral cavity. In addition, it helps in the detection of the borders in both surgical biopsy and surgical excision. |
Author | Mashlah, Ammar Sawan, Dania |
AuthorAffiliation | Department of Oral Medicine, Damascus University, Damascus, Syria |
AuthorAffiliation_xml | – name: Department of Oral Medicine, Damascus University, Damascus, Syria |
Author_xml | – sequence: 1 givenname: Dania surname: Sawan fullname: Sawan, Dania organization: Department of Oral Medicine, Damascus University, Damascus, Syria – sequence: 2 givenname: Ammar surname: Mashlah fullname: Mashlah, Ammar organization: Department of Oral Medicine, Damascus University, Damascus, Syria |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/26236687$$D View this record in MEDLINE/PubMed |
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Keywords | fluorescent light VELscope malignancy Biopsy premalignancy specificity sensitivity |
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Snippet | The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope).
A total of 748 patients were... Aim: The purpose of this study was the early detection of premalignant and malignant oral soft lesions by fluorescent light (VELscope). Materials and Methods:... |
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Title | Evaluation of premalignant and malignant lesions by fluorescent light (VELscope) |
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