Chronic psychosocial stress does not affect the number of pyramidal neurons in tree shrew hippocampus

• Published in: Neuroscience letters Vol. 233; no. 2; pp. 121 - 124
• Main Authors: Vollmann-Honsdorf, Gesa K, Flügge, Gabriele, Fuchs, Eberhard
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 19.09.1997; Elsevier
• Subjects: Animals; Behavioral psychophysiology; Biological and medical sciences; Cell Count; Chronic Disease; Cortisol; Degeneration; Fundamental and applied biological sciences. Psychology; Hippocampus; Hippocampus - pathology; Hippocampus - physiopathology; Hydrocortisone - urine; Male; Miscellaneous; Neuronal loss; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Psychosocial stress; Pyramidal Cells - cytology; Pyramidal Cells - physiology; Shrews; Stereology; Stress, Psychological - physiopathology; Stress, Psychological - urine; Tree shrew; Neuronal loss; Tree shrew; Psychosocial stress; Stereology; Cortisol; Degeneration; Hippocampus; Tupaia belangeri; Central nervous system; Hydrocortisone; Glucocorticoid; Stress; Scandentia; Vertebrata; Mammalia; Animal; Adrenal hormone; Pyramidal neuron; Brain (vertebrata)

Exposure of the hippocampus for prolonged periods to an excess of glucocorticoids is thought to result in damage and finally loss of pyramidal neurons. By applying improved methods for quantifying cell numbers we investigated whether chronic psychosocial stress in tree shrews reduces the total numbe...