LGL leukemia and HTLV

• Published in: AIDS research and human retroviruses Vol. 26; no. 1; p. 33
• Main Authors: Thomas, Anish, Perzova, Raisa, Abbott, Lynn, Benz, Patricia, Poiesz, Michael J, Dube, Syamalima, Loughran, Thomas, Ferrer, Jorge, Sheremata, William, Glaser, Jordan, Leon-Ponte, Matilde, Poiesz, Bernard J
• Format: Journal Article
• Language: English
• Published: United States 01.01.2010
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies, Viral - blood; Blotting, Western - methods; Cross Reactions; Endogenous Retroviruses - immunology; Enzyme-Linked Immunosorbent Assay - methods; Female; HIV-2 - genetics; HIV-2 - immunology; HIV-2 - isolation & purification; Human T-lymphotropic virus 1 - genetics; Human T-lymphotropic virus 1 - immunology; Human T-lymphotropic virus 1 - isolation & purification; Human T-lymphotropic virus 2 - genetics; Human T-lymphotropic virus 2 - immunology; Human T-lymphotropic virus 2 - isolation & purification; Human T-lymphotropic virus 3 - genetics; Human T-lymphotropic virus 3 - immunology; Human T-lymphotropic virus 3 - isolation & purification; Humans; Leukemia Virus, Bovine - immunology; Leukemia, Large Granular Lymphocytic - virology; Male; Middle Aged; Polymerase Chain Reaction - methods; Seroepidemiologic Studies; Young Adult

Samples were obtained from 53 large granular lymphocytic leukemia (LGLL) patients and 10,000 volunteer blood donors (VBD). Sera were screened in an HTLV-1 enzyme immunoassay (EIA) and further analyzed in peptide-specific Western blots (WB). DNAs were analyzed by HTLV-1, -2, -3, and -4-specific PCR....