The NIMA-related kinase family and cancer

• Published in: Frontiers in oncology Vol. 15; p. 1556917
• Main Authors: Li, Haotian, Li, Junhan, Zhang, Yue, Cao, Ran, Guo, Congcong, Jiao, Mingwen
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 27.03.2025
• Subjects: cancer; metastasis; mitosis; NEK family; Oncology; proliferation; therapeutic target; NEK family; cancer; therapeutic target; proliferation; mitosis; metastasis

Cancer is a disease where cells begin to divide uncontrollably and spread to other parts of the body. Mitotic kinases play a crucial role in the initiation and progression of all human malignancies, making them common therapeutic targets. However, a significant portion of the human kinome has yet to...