Clinical value of heparin-binding protein in adult bacterial intracranial infection

• Published in: Frontiers in cellular and infection microbiology Vol. 14; p. 1439143
• Main Authors: Guan, Linsai, Wang, Feiyao, Chen, Jingni, Xu, Yanxin, Zhang, Weixing, Zhu, Jianping
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 14.11.2024
• Subjects: Adult; Aged; Antimicrobial Cationic Peptides - blood; Biomarkers - blood; Blood Proteins - analysis; C-Reactive Protein - analysis; C-Reactive Protein - metabolism; Cellular and Infection Microbiology; cerebrospinal fluid; China; Female; gram - negative bacteria; gram - positive bacteria; Gram-Negative Bacteria - isolation & purification; Gram-Negative Bacterial Infections - blood; Gram-Negative Bacterial Infections - diagnosis; Gram-Negative Bacterial Infections - microbiology; Gram-Positive Bacteria - isolation & purification; Gram-Positive Bacterial Infections - blood; Gram-Positive Bacterial Infections - diagnosis; Gram-Positive Bacterial Infections - microbiology; heparin binding protein; Humans; intracranial infection; Male; Middle Aged; Procalcitonin - blood; ROC Curve; Sensitivity and Specificity; China; intracranial infection; heparin binding protein; gram - negative bacteria; gram - positive bacteria; cerebrospinal fluid

The accurate and sensitive diagnosis of intracranial infection continues to pose a critical challenge. This study aimed to probe into the clinical value of heparin binding protein (HBP) in bacterial intracranial infection. Patients suspected of having bacterial intracranial infection and admitted to...