Long term methylphenidate exposure and growth in children and adolescents with ADHD. A systematic review and meta-analysis

• Published in: Neuroscience and biobehavioral reviews Vol. 120; pp. 509 - 525
• Main Authors: Carucci, Sara, Balia, Carla, Gagliano, Antonella, Lampis, Angelico, Buitelaar, Jan K., Danckaerts, Marina, Dittmann, Ralf W., Garas, Peter, Hollis, Chris, Inglis, Sarah, Konrad, Kerstin, Kovshoff, Hanna, Liddle, Elizabeth B., McCarthy, Suzanne, Nagy, Peter, Panei, Pietro, Romaniello, Roberta, Usala, Tatiana, Wong, Ian C.K., Banaschewski, Tobias, Sonuga-Barke, Edmund, Coghill, David, Zuddas, Alessandro
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.01.2021
• Subjects: Adolescent; Attention Deficit Disorder with Hyperactivity - drug therapy; Attention deficit/hyperactivity disorder (ADHD); Body Weight; Central Nervous System Stimulants - therapeutic use; Child; growth; height; Humans; methylphenidate; Methylphenidate - therapeutic use; Prospective Studies; puberty; stimulants; Treatment Outcome; weight; methylphenidate; stimulants; Attention deficit/hyperactivity disorder (ADHD); weight; growth; puberty; height

•MPH is a very effective treatment for ADHD but there are concerns about potential adverse effects of extended treatment on several systems, including growth.•Long term MPH appears to be associated with a statistically significant impact on height and weight in ADHD children and adolescents, but eff...