Cilostazol Suppresses Aβ-induced Neurotoxicity in SH-SY5Y Cells through Inhibition of Oxidative Stress and MAPK Signaling Pathway - Oguchi, Tatsunori; Ono, Ran; Tsuji, Mayumi; Shozawa, Hidenobu; Somei, Masayuki; Inagaki, Manami; Mori, Yukiko; Yasumoto, Taro; Ono, Kenjiro; Kiuchi, Yuji (Frontiers in aging neuroscience, 2017)
Keywords: Acetylcholinesterase; Adenine; Alzheimer's disease; AMP; Amyloid; amyloid β; Annexin V; Apoptosis; BAX protein; Bcl-2 protein; Biomarkers; Brain; Caspase; Caspase-3; Cell viability; cilostazol; Cognitive ability; Cyclic AMP response element-binding protein; Dementia disorders; Disease; Extracellular signal-regulated kinase; Gene expression; Ischemia; Kinases; MAP kinase; Medical research; Mitochondria; NAD(P)H oxidase; Neurodegeneration; Neurofibrillary tangles; Neuroscience; Neurotoxicity; Oxidative stress; Pathogenesis; Peptides; Proteins; Reactive oxygen species; Senile plaques; Signal transduction; Superoxide dismutase; United States--US; Japan; neurotoxicity; Alzheimer’s disease; amyloid β; NADPH oxidase; cilostazol; apoptosis; MAPK; oxidative stress