Reconstitution experiments show that sequence-specific histone-DNA interactions are the basis for nucleosome phasing on mouse satellite DNA

• Published in: Cell Vol. 42; no. 1; pp. 281 - 290
• Main Authors: Linzweiler, Winfried, Hörz, Wolfram
• Format: Journal Article
• Language: English
• Published: Cambridge, MA Elsevier Inc 01.01.1985; Cell Press
• Subjects: Animals; Base Sequence; Biological and medical sciences; Chromatin. Chromosome; DNA - metabolism; DNA, Satellite - metabolism; Exodeoxyribonucleases - metabolism; Fundamental and applied biological sciences. Psychology; Histones - metabolism; Mice; Molecular and cellular biology; Molecular genetics; Nucleosomes - metabolism; Repetitive Sequences, Nucleic Acid; Chromatin; Nucleosome; Rodentia; Molecular interaction; Satellite DNA; In vivo; Vertebrata; Mammalia; Mouse; DNA; Histone; Localization; Comparative study
• ISSN: 0092-8674
• DOI: 10.1016/S0092-8674(85)80123-9

The molecular basis underlying the sequence-specific positioning of nucleosomes on DNA was investigated. We previously showed that histone octamers occupy multiple specific positions on mouse satellite DNA in vivo and have now reconstituted the 234 by mouse satellite repeat unit with pure core histo...