Absence of causative genetic association between Helicobacter pylori infection and glaucoma: a bidirectional two-sample mendelian randomization study

• Published in: Frontiers in genetics Vol. 15; p. 1368915
• Main Authors: Zhang, Yan, Huang, Yihong, Wu, Yuyu, Zhang, Jinying, Chen, Wanzhu, Xu, Danfeng, Guo, Maosheng
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 24.05.2024
• Subjects: Genetics; Helicobacter pylori; mendelian randomization; normal tension glaucoma; primary open-angle glaucoma; pseudo-exfoliation glaucoma; pseudo-exfoliation glaucoma; normal tension glaucoma; Helicobacter pylori; primary open-angle glaucoma; mendelian randomization

Background: While clinical research has indicated a potential link between Helicobacter pylori infection and the onset of glaucoma, the causality of this association remains uncertain due to the susceptibility of observational studies to confounding factors and reverse causation. Methods: A comprehe...