Lipid peroxidation: Mechanisms, inhibition, and biological effects

• Published in: Biochemical and biophysical research communications Vol. 338; no. 1; pp. 668 - 676
• Main Authors: Niki, Etsuo, Yoshida, Yasukazu, Saito, Yoshiro, Noguchi, Noriko
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 09.12.2005
• Subjects: Animals; Antioxidant; Cholesterol; HODE; Humans; Linoleic acid; Lipid peroxidation; Lipid Peroxidation - physiology; Lipid Peroxides - antagonists & inhibitors; Lipid Peroxides - chemistry; Lipid Peroxides - metabolism; Lipid Peroxides - physiology; Oxysterols; Vitamin E; Vitamin E; Oxysterols; Lipid peroxidation; HODE; Antioxidant; Cholesterol; Linoleic acid

In the last 50 years, lipid peroxidation has been the subject of extensive studies from the viewpoints of mechanisms, dynamics, product analysis, involvement in diseases, inhibition, and biological signaling. Lipids are oxidized by three distinct mechanisms; enzymatic oxidation, non-enzymatic, free...