Positron emission tomographic analysis of cerebral structures activated specifically by repetitive noxious heat stimuli

• Published in: Journal of neurophysiology Vol. 71; no. 2; p. 802
• Main Authors: Casey, K L, Minoshima, S, Berger, K L, Koeppe, R A, Morrow, T J, Frey, K A
• Format: Journal Article
• Language: English
• Published: United States 01.02.1994
• Subjects: Adult; Afferent Pathways - physiology; Brain - blood supply; Brain - diagnostic imaging; Brain Mapping; Energy Metabolism - physiology; Female; Humans; Male; Nociceptors - physiology; Pain Threshold - physiology; Reference Values; Skin - innervation; Skin Temperature - physiology; Thermoreceptors - physiology; Thermosensing - physiology; Tomography, Emission-Computed

1. To identify the forebrain and brain stem structures that are active during the perception of acute heat pain in humans, we performed H2 15O positron emission tomographic (PET) analyses of cerebral blood flow (CBF) on nine normal volunteers while they received repetitive noxious (50 degrees C) and...