Hyaluronidase-responsive hydrogel loaded with magnetic nanoparticles combined with external magnetic stimulation for spinal cord injury repair

• Published in: Materials today bio Vol. 30; p. 101378
• Main Authors: Fan, Zhiyi, Zhang, Guofu, Zhan, Wanda, Wang, Juehan, Wang, Chaoyong, Yue, QianYing, Huang, Zhangheng, Wang, Yongxiang
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.02.2025; Elsevier
• Subjects: Hyaluronidase; Hydrogel; Magnetic field; Spinal cord injury; Hyaluronidase; H&E; mT; DAPI; LFB; Spinal cord injury; NGF; GAG; Gel; TUJ1; DMEM; SD; GAP43; FBS; SCI; HA; MEP; SEM; Hydrogel; CSPGs; Magnetic field

Spinal cord injury (SCI) is a neurological condition that causes significant loss of sensory, motor, and autonomic functions below the level of injury. Current clinical treatment strategies often fail to meet expectations. Hyaluronidase is typically associated with tumor progression and bacterial in...