Association of FcγRIIa Polymorphism with Clinical Outcome of Dengue Infection: First Insight from Pakistan

• Published in: The American journal of tropical medicine and hygiene Vol. 93; no. 4; pp. 691 - 696
• Main Authors: Mohsin, Saima Naz, Mahmood, Saqib, Amar, Ali, Ghafoor, Farkhanda, Raza, Syed Mohsin, Saleem, Mahjabeen
• Format: Journal Article
• Language: English
• Published: United States The American Society of Tropical Medicine and Hygiene 01.10.2015
• Subjects: Adolescent; Asymptomatic Infections; Child; Child, Preschool; Dengue - genetics; Female; Genetic Association Studies; Genetic Predisposition to Disease - genetics; Genotype; Humans; Infant; Male; Pakistan - epidemiology; Polymorphism, Single Nucleotide - genetics; Receptors, IgG - genetics; Severe Dengue - genetics; Treatment Outcome; Young Adult; Pakistan

Dengue illness has been a major health concern in Pakistan during the last decade. Dengue infection can result in a spectrum of clinically distinct outcomes, ranging from asymptomatic infection to potentially life-threatening forms of dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). A...