Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity

• Published in: American journal of physiology. Heart and circulatory physiology Vol. 294; no. 2; pp. H613 - H621
• Main Authors: Bell, James R, Kennington, Erika, Fuller, William, Dighe, Kushal, Donoghue, Pamela, Clark, James E, Jia, Li-Guo, Tucker, Amy L, Randall Moorman, J, Marber, Michael S, Eaton, Philip, Dunn, Michael J, Shattock, Michael J
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.02.2008
• Subjects: Action Potentials - physiology; Adenosine triphosphatase; Animals; Biochemistry; Blood Pressure - physiology; Calcium - pharmacology; Cardiology; Electrophoresis, Gel, Two-Dimensional; Heart; Heart - physiology; Heart Conduction System - physiology; In Vitro Techniques; Kinases; Membrane Proteins - genetics; Membrane Proteins - physiology; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium - enzymology; Organ Size - physiology; Phenotype; Phosphoproteins - genetics; Phosphoproteins - physiology; Potassium; Rodents; Sodium; Sodium-Potassium-Exchanging ATPase - metabolism; Ventricular Function, Left - physiology

1 Cardiovascular Division, King's College London, Rayne Institute, St Thomas' Hospital, London, United Kingdom; 2 Proteome Research Centre, Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland; and 3 Cardiovascular Division, Departm...