Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: The LUNA study

• Published in: Experimental eye research Vol. 84; no. 4; pp. 718 - 728
• Main Authors: Trieschmann, Meike, Beatty, Stephen, Nolan, John M., Hense, Hans Werner, Heimes, Britta, Austermann, Ulrike, Fobker, Manfred, Pauleikhoff, Daniel
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.04.2007
• Subjects: age-related macular degeneration; Aged; Aged, 80 and over; Antioxidants - administration & dosage; Dietary Supplements; Female; Humans; Lipoproteins, HDL - blood; lutein; Lutein - administration & dosage; Lutein - blood; Macula Lutea - metabolism; Macular Degeneration - blood; Macular Degeneration - metabolism; macular pigment; Male; Middle Aged; Ocuvite Lutein; Xanthophylls - administration & dosage; Xanthophylls - blood; zeaxanthin; Zeaxanthins; Ocuvite Lutein; age-related macular degeneration; lutein; macular pigment; zeaxanthin

Macular pigment (MP), consisting of lutein (L) and zeaxanthin (Z), is believed to protect the retina from photo-oxidative damage. The current study investigates, in terms of MP optical density (MPOD) and serum concentrations of its constituent carotenoids, response to supplemental L and Z, and co-an...