First PGT-A using human in vivo blastocysts recovered by uterine lavage: comparison with matched IVF embryo controls

• Published in: Human reproduction (Oxford) Vol. 35; no. 1; pp. 70 - 80
• Main Authors: Munné, Santiago, Nakajima, Steven T, Najmabadi, Sam, Sauer, Mark V, Angle, Marlane J, Rivas, José L, Mendieta, Laura V, Macaso, Thelma M, Sawarkar, Sarthak, Nadal, Alexander, Choudhary, Kajal, Nezhat, Camran, Carson, Sandra A, Buster, John E
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 01.01.2020
• Subjects: Aneuploidy; Blastocyst; Female; Fertilization in Vitro; Genetic Testing; Humans; Infertility; Original; Prospective Studies; Therapeutic Irrigation; uterine lavage; morphology; next-generation sequencing; preimplantation genetic testing for aneuploidy; IVF; blastocyst; reciprocal pregnancy for lesbian couples; in vivo

Abstract STUDY QUESTION After controlled ovarian stimulation (COS) and IUI, is it clinically feasible to recover in vivo conceived and matured human blastocysts by uterine lavage from fertile women for preimplantation genetic testing for aneuploidy (PGT-A) and compare their PGT-A and Gardner scale m...