Adventitial Cells and Perictyes Support Chondrogenesis Through Different Mechanisms in 3-Dimensional Cultures With or Without Nanoscaffolds

• Published in: Journal of biomedical nanotechnology Vol. 11; no. 10; p. 1799
• Main Authors: Zhang, Shu, Ba, Kai, Wu, Ling, Lee, Siyong, Peault, Bruno, Petrigliano, Frank A, McAllister, David R, Adams, John S, Evseenko, Denis, Lin, Yunfeng
• Format: Journal Article
• Language: English
• Published: United States 01.10.2015
• Subjects: Adventitia - cytology; Adventitia - physiology; Cell Differentiation - physiology; Cell Proliferation; Cell Survival; Cells, Cultured; Chondrocytes - cytology; Chondrocytes - physiology; Chondrogenesis - physiology; Equipment Design; Equipment Failure Analysis; Humans; Nanoparticles - chemistry; Nanoparticles - ultrastructure; Pericytes - cytology; Pericytes - physiology; Polyesters - chemistry; Printing, Three-Dimensional; Tissue Engineering - instrumentation; Tissue Engineering - methods; Tissue Scaffolds

In previous studies, mesenchymal stromal cells (MSCs) derived from bone marrow and fat tissues were shown to increase proliferation and matrix production of chondrocytes (CH) in co-culture. The aim of this study was to investigate the roles of pericytes (CD31(neg)CD45(neg)CD146+CD34(neg)) and advent...