All roads lead to Rome: the plasticity of gut microbiome drives the extensive adaptation of the Yarkand toad-headed agama (Phrynocephalus axillaris) to different altitudes

• Published in: Frontiers in microbiology Vol. 15; p. 1501684
• Main Authors: Du, Jianghao, Zheng, Peng, Gao, Weizhen, Liang, Qianru, Leng, Lin, Shi, Lei
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 08.01.2025
• Subjects: 16S rRNA; altitude gradients; gut microbiome; LC-MS metabolomics; Microbiology; Phrynocephalus axillaris; plasticity; LC-MS metabolomics; 16S rRNA; Phrynocephalus axillaris; altitude gradients; plasticity; gut microbiome

The gut microbiome was involved in a variety of physiological processes and played a key role in host environmental adaptation. However, the mechanisms of their response to altitudinal environmental changes remain unclear. In this study, we used 16S rRNA sequencing and LC-MS metabolomics to investig...