Myofibroblast Deficiency of LSD1 Alleviates TAC-Induced Heart Failure

• Published in: Circulation research Vol. 129; no. 3; pp. 400 - 413
• Main Authors: Huo, Jin-Ling, Jiao, Lemin, An, Qi, Chen, Xiuying, Qi, Yuruo, Wei, Bingfei, Zheng, Yichao, Shi, Xiaojing, Gao, Erhe, Liu, Hong-Min, Chen, Dong, Wang, Cong, Zhao, Wen
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 23.07.2021
• Subjects: Animals; Aortic Valve Stenosis - complications; Cells, Cultured; Heart Failure - etiology; Heart Failure - metabolism; Heart Failure - physiopathology; Histone Demethylases - genetics; Histone Demethylases - metabolism; Humans; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocytes, Cardiac - metabolism; Myofibroblasts - metabolism; Myofibroblasts - pathology; p38 Mitogen-Activated Protein Kinases - metabolism; Rats; Rats, Sprague-Dawley; Smad Proteins - metabolism; Transforming Growth Factor beta - metabolism; heart failure; fibrosis; histone; hypertrophy; myofibroblast

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