Developmental toxicity of carbon black oil in mice

• Published in: Teratology (Philadelphia) Vol. 62; no. 4; p. 227
• Main Authors: Hansen, J M, Reynolds, P R, Booth, G M, Schaalje, G B, Seegmiller, R E
• Format: Journal Article
• Language: English
• Published: United States 01.10.2000
• Subjects: Abnormalities, Drug-Induced - etiology; Administration, Oral; Animals; Body Weight - drug effects; Carbon - toxicity; Data Interpretation, Statistical; Embryo, Mammalian - drug effects; Embryonic and Fetal Development - drug effects; Female; Fetal Weight - drug effects; Litter Size - drug effects; Liver - drug effects; Liver - embryology; Maternal Exposure; Maternal-Fetal Exchange - drug effects; Mice; Pregnancy

Carbon black oil (CBO) is a refinery side-stream product used to produce asphalt and other commercial products. CBO contains several classes of hydrocarbons, several of which are known to exhibit systemic and gestational toxicities, making this mixture a candidate for causing reproductive toxicity....