Clinical Evaluation of Blood Pressure Lowering, Endothelial Function Improving, Hypolipidemic and Anti-Inflammatory Effects of Pomegranate Juice in Hypertensive Subjects

• Published in: Phytotherapy research Vol. 28; no. 2; pp. 193 - 199
• Main Authors: Asgary, Sedigheh, Sahebkar, Amirhossein, Afshani, Mohammad Reza, Keshvari, Mahtab, Haghjooyjavanmard, Shaghayegh, Rafieian-Kopaei, Mahmoud
• Format: Journal Article
• Language: English
• Published: England Blackwell Publishing Ltd 01.02.2014; Wiley Subscription Services, Inc
• Subjects: adhesion; Adult; Aged; alternative medicine; Anthocyanins - chemistry; Anti-Inflammatory Agents - pharmacology; Antioxidants - pharmacology; apolipoproteins; Apolipoproteins A - blood; Apolipoproteins B - blood; atherosclerosis; Beverages; biomarkers; blood lipids; blood pressure; Blood Pressure - drug effects; blood serum; C-reactive protein; C-Reactive Protein - metabolism; clinical examination; Dietary Supplements; dinner; E-Selectin - blood; Female; Fruit - chemistry; Humans; Hypertension - drug therapy; Hypolipidemic Agents - pharmacology; intercellular adhesion molecule-1; Intercellular Adhesion Molecule-1 - metabolism; interleukin-6; Interleukin-6 - metabolism; lipid composition; Lipids - blood; lunch; Male; Middle Aged; phytotherapy; polyphenols; Polyphenols - pharmacology; pomegranate juice; pomegranates; pro-inflammatory cytokines; Punica granatum; Punicaceae - chemistry; Single-Blind Method; Vascular Cell Adhesion Molecule-1 - blood; vascular cell adhesion molecules; atherosclerosis; blood pressure; alternative medicine; pro-inflammatory cytokines

Pomegranate (Punica granatum L.) juice (PJ) contains different types of antioxidants and bioactive polyphenols and has been reported to promote cardiovascular health through several mechanisms. The present study aimed to examine the effects of 2‐week intake of fresh PJ on blood pressure, flow‐mediat...