Visible‐Light‐Promoted Regio‐ and Stereoselective Oxyalkenyl‐ation of Phosphinyl Allenes

• Published in: Advanced synthesis & catalysis Vol. 362; no. 13; pp. 2701 - 2708
• Main Authors: Sun, Xue, Liu, Teng, Yang, Yan‐Tong, Gu, Yue‐Jie, Liu, Yu‐Wei, Ji, Yi‐Gang, Luo, Kai, Zhu, Jie, Wu, Lei
• Format: Journal Article
• Language: English
• Published: WEINHEIM Wiley 16.07.2020; Wiley Subscription Services, Inc
• Subjects: Chemistry; Chemistry, Applied; Chemistry, Organic; Conjugated Tertiary Allylic Alcohol derivatives; Functional groups; Oxyalkenylation; Palladium; Palladium Catalysis; Phosphinyl Allenes; Physical Sciences; Science & Technology; Stereoselectivity; Visible Light; CATALYSIS; MECHANISM; Oxyalkenylation; Palladium Catalysis; Conjugated Tertiary Allylic Alcohol derivatives; Phosphinyl Allenes; OXYGEN; FUNCTIONALIZATION; Visible Light; SYNTHETIC APPLICATIONS; AEROBIC OXIDATION; PHTHALOCYANINES; CYCLIZATION; TRIFLUOROMETHYLATION; PHOTOOXIDATION

A highly regio‐ and stereoselective oxyalkenylation of phosphinyl allenes is revealed for the first time. This protocol, merging visible light photoredox and palladium catalysis, provides a direct approach to conjugated tertiary allylic alcohol derivatives with broad functional group tolerance in mo...