Alzheimer's diagnosis beyond cerebrospinal fluid: Probe-Free Detection of Tau Proteins using MXene based redox systems and molecularly imprinted polymers

• Published in: Biosensors and bioelectronics. X Vol. 20; p. 100513
• Main Authors: Arjun, Ajith Mohan, Deshpande, Sudhaunsh, Dunlop, Tom, Norman, Beth, Oliviera, Daniela, Vulpe, Georgeta, Moreira, Felismina, Sharma, Sanjiv
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.10.2024; Elsevier

Phosphorylated Tau proteins are promising biomarkers for the diagnosis and prognosis of Alzheimer's disease. This study presents a novel voltametric sensor using a vanadium MXene polydopamine (VxPDA) redox active composite and a Tau-441-specific polyaniline molecularly imprinted polymer (PANI M...