Single nucleotide polymorphisms of matrix metallopeptidase 3 and risk of gliomas in a Chinese Han population

• Published in: Molecular carcinogenesis Vol. 51; no. S1; pp. E1 - E10
• Main Authors: Fan, Weiwei, Zhou, Keke, Hu, Dezhi, Song, Xiao, Zhao, Yingjie, Chen, Hongyan, Wei, Qingyi, Chen, Gong, Shi, Jinlong, Du, Guhong, Mao, Ying, Lu, Daru, Zhou, Liangfu
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.10.2012; Wiley Subscription Services, Inc
• Subjects: Adult; Asian Continental Ancestry Group - genetics; Brain tumors; Cancer; Case-Control Studies; Central Nervous System Neoplasms - genetics; China; cumulative effect; Enzymes; Female; Genetic Predisposition to Disease; genetic susceptibility; glioma; Glioma - genetics; Haplotypes - genetics; Humans; Male; Matrix Metalloproteinase 3 - genetics; Middle Aged; MMP3; Odds Ratio; Peptides; Polymorphism; Polymorphism, Single Nucleotide; Population genetics; Promoter Regions, Genetic; Risk Factors; China
• ISSN: 0899-1987; 1098-2744; 1098-2744
• DOI: 10.1002/mc.20842

Matrix metallopeptidases (MMPs) play an important role in central nervous system tumor growth, invasion and spreading. The currently available data provide clear evidence for the involvement of MMP3 in the pathophysiology of glioma. The study aims to explore the association of single nucleotide poly...