CEPHALOSPORINS HAVING A HETEROCYCLIC CATECHOL IN THE C3 SIDE CHAIN: II. IMPROVEMENT OF PHARMACOKINETIC PROFILE - KAMACHI, HAJIME; HASEGAWA, TOSHIFUMI; KAMEI, HIDEO; IMAE, KIYOTO; OKITA, TAKAAKI; TAMAOKA, MASAMI; MURATA, SHINJI; IIMURA, SEIJI (Journal of antibiotics, 1993)
Keywords: Animals; Antibacterial agents; Antibiotics. Antiinfectious agents. Antiparasitic agents; Bacterial Infections - drug therapy; Biological and medical sciences; Ceftazidime - pharmacology; Cephalosporins - blood; Cephalosporins - chemical synthesis; Cephalosporins - pharmacokinetics; Half-Life; Medical sciences; Mice; Microbial Sensitivity Tests; Pharmacology. Drug treatments; Structure-Activity Relationship; Molecular structure; Intramuscular administration; Optimization; Synthesis; Structure activity relation; Bacteria; Heterocyclic compound; Rodentia; Bioavailability; In vitro; Infection; In vivo; Vertebrata; Antibiotic; Chemotherapy; Cephalosporin derivatives; Mammalia; Sensitivity resistance; Treatment; Mouse; Animal; Bacteriosis; Microorganism culture; Antibacterial agent; Pharmacokinetics