Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo - Lu, Jing; Miao, Junye; Su, Tao; Liu, Ying; He, Rongqiao (Biochimica et biophysica acta, 2013)
Keywords: Alzheimer disease; Animals; brain; catalytic activity; Cell Line, Tumor; cytoplasm; Formaldehyde; Formaldehyde - pharmacology; glycogen (starch) synthase; Glycogen Synthase Kinase 3 - physiology; Glycogen Synthase Kinase 3 beta; GSK-3β; high performance liquid chromatography; immunocytochemistry; lithium chloride; memory; Mice; Nuclear accumulation; patients; Phosphorylation; polymerization; polymers; Protein Multimerization - drug effects; Protein polymerization; RNA interference; Tau hyperphosphorylation; tau Proteins - chemistry; tau Proteins - metabolism; tau-protein kinase; Tauopathy; Western blotting; PHFs; GSK-3β; AD; NFTs; Tau hyperphosphorylation; Protein polymerization; Nuclear accumulation; FA; pTau; Tauopathy; Formaldehyde