(S)-norketamine and (2S,6S)-hydroxynorketamine exert potent antidepressant-like effects in a chronic corticosterone-induced mouse model of depression - Yokoyama, Rei; Higuchi, Momoko; Tanabe, Wataru; Tsukada, Shinji; Naito, Megumi; Yamaguchi, Takumi; Chen, Lu; Kasai, Atsushi; Seiriki, Kaoru; Nakazawa, Takanobu; Nakagawa, Shinsaku; Hashimoto, Kenji; et al. (Pharmacology, biochemistry and behavior, 2020)
Keywords: Anhedonia - drug effects; Animals; Anti-anhedonic; Antidepressant; Antidepressive Agents - administration & dosage; Antidepressive Agents - pharmacology; Behavior, Animal - drug effects; Behaviors; C57BL/6J mice; Corticosterone - administration & dosage; Corticosterone - pharmacology; Depression - chemically induced; Depression - drug therapy; Depression model; Disease Models, Animal; Female; Ketamine - administration & dosage; Ketamine - analogs & derivatives; Ketamine - pharmacology; Ketamine metabolites; Locomotion - drug effects; Male; Mice; Mice, Inbred C57BL; Receptors, N-Methyl-D-Aspartate - antagonists & inhibitors; Antidepressant; Anti-anhedonic; Behaviors; Ketamine metabolites; C57BL/6J mice; Depression model