Comparative evaluation of saliva collection methods for proteome analysis

• Published in: Clinica chimica acta Vol. 419; pp. 42 - 46
• Main Authors: Golatowski, Claas, Gesell Salazar, Manuela, Dhople, Vishnu Mukund, Hammer, Elke, Kocher, Thomas, Jehmlich, Nico, Völker, Uwe
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 18.04.2013
• Subjects: Adult; Collection method; Female; Humans; LC–MS/MS; Male; Proteome - analysis; Saliva; Saliva - chemistry; Saliva - metabolism; Salivary Proteins and Peptides - analysis; Sensitivity and Specificity; Specimen Handling; Whole saliva proteomics; Whole saliva proteomics; Saliva; LC–MS/MS; Collection method

Saliva collection devices are widely used for large-scale screening approaches. This study was designed to compare the suitability of three different whole-saliva collection approaches for subsequent proteome analyses. From 9 young healthy volunteers (4 women and 5 men) saliva samples were collected...