TAK-925, an orexin 2 receptor-selective agonist, shows robust wake-promoting effects in mice - Yukitake, Hiroshi; Fujimoto, Tatsuhiko; Ishikawa, Takashi; Suzuki, Atsushi; Shimizu, Yuji; Rikimaru, Kentaro; Ito, Mitsuhiro; Suzuki, Motohisa; Kimura, Haruhide (Pharmacology, biochemistry and behavior, 2019)
Keywords: Hypersomnia; Narcolepsy; Orexin; Orexin 2 receptor; Orexin 2 receptor agonist; TAK-925; BBB; DMSO; CHO; BSA; EDS; FBS; IC50; Orexin 2 receptor agonist; EC50; qPCR; EMG; EEG; NT1; OX2R; ROI; ssODN; GPCR; ZT; ERK; TAK-925; Hypersomnia; NREM; Orexin 2 receptor; OX1R; PPN; SC; CREB; CSF; HDR; TTX; Narcolepsy; VLP; WT; Orexin; HTRF; KO; h; ACSF; IP1; EDTA; TMN; HEPES; LC; OX-A; SCH; HBSS; OX-B; REM; ICV