Neuroendocrine response to diclofenac in healthy subjects: a pilot study

• Published in: Journal of endocrinological investigation Vol. 46; no. 12; pp. 2617 - 2627
• Main Authors: Varaldo, E., Sibilla, M., Bioletto, F., Cuboni, D., Prencipe, N., Bona, C., Ferrari, M., Viglino, F., Aversa, L. S., Grottoli, S., Ghigo, E., Gasco, V., Berton, A. M.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.12.2023; Springer Nature B.V
• Subjects: Adrenocorticotropic hormone; Antidiuretics; Cortisol; Diclofenac; Endocrinology; Hormones; Inflammation; Internal Medicine; Medicine; Medicine & Public Health; Metabolic Diseases; Neuroendocrine system; Nonsteroidal anti-inflammatory drugs; Original Article; Pilot projects; Placebos; Secretion; Urine; Vasopressin; MR-proANP; Prostaglandins; MR-proADM; Arginine-vasopressin; NSAIDs; Copeptin

Purpose The precise effects of non-steroidal anti-inflammatory drugs on the neuroendocrine hydro-electrolytic regulation are not precisely understood. The aim of this pilot study was to evaluate, in healthy subjects, the neuroendocrine response of the antidiuretic system to intravenous diclofenac in...