Compliance with Prescribing and Dispensing Conditions for Valproate and Related Substances in Girls and Women of Childbearing Potential: A Survey of Community Pharmacists in France

• Published in: Drug safety Vol. 46; no. 2; pp. 121 - 128
• Main Authors: Fauvelle, Khristina, Bigna, Jean Joel
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.02.2023; Springer Nature B.V
• Subjects: Bipolar disorder; Compliance; Confidence intervals; Congenital diseases; Contraindications; Dispensing; Drug Prescriptions; Drug Safety and Pharmacovigilance; Drug stores; Educational materials; Epilepsy; Female; Girls; Humans; Medical personnel; Medicine; Medicine & Public Health; Neurodevelopmental disorders; Optimization; Oral administration; Original Research Article; Patients; Pharmacists; Pharmacology/Toxicology; Pregnancy; Prenatal experience; Prenatal exposure; Prenatal Exposure Delayed Effects; Professional ethics; Questionnaires; Risk; Risk reduction; Statistical analysis; Surveys; Surveys and Questionnaires; Valproic acid; Valproic Acid - adverse effects; Women; Womens health; France

Introduction Prenatal exposure to valproate and related substances is associated with a risk of malformations and/or neurodevelopmental disorders. In France, prescription and dispensing conditions of oral valproate forms are subject to risk minimization measures for girls and women of childbearing p...