A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research
Piper longum, commonly referred as ‘Pippali’, has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy,...
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| Published in | Journal of ethnopharmacology Vol. 247; no. NA; p. 112255 |
|---|---|
| Main Authors | , , |
| Format | Journal Article |
| Language | English |
| Published |
Ireland
Elsevier B.V
30.01.2020
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Piper longum, commonly referred as ‘Pippali’, has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc.
This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant.
This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967–2019.
Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom.
Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body.
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| AbstractList | Piper longum, commonly referred as ‘Pippali’, has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc.
This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant.
This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967–2019.
Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom.
Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body.
[Display omitted] Piper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc. AIM OF THE REVIEW: This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant. This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967-2019. Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom. Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body. Piper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc. AIM OF THE REVIEW: This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant.ETHNOPHARMACOLOGICAL RELEVANCEPiper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc. AIM OF THE REVIEW: This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant.This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967-2019.MATERIALS AND METHODSThis systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967-2019.Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom.RESULTSMany phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom.Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body.CONCLUSIONAmongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body. Ethnopharmacological relevance Piper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc. Aim of the review This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant. Materials and methods This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967-2019. Results: Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom. Conclusion: Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and anti-diabetic activity. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body. Graphical abstract Image 1 Piper longum, commonly referred as ‘Pippali’, has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic, carminative, anti-diarrhoeic, immunostimulant, post childbirth to check postpartum hemorrhage and to treat asthma, insomnia, dementia, epilepsy, diabetes, rheumatoid arthritis, asthma, spleen disorder, puerperal fever, leprosy etc.This review offers essential data focusing on the traditional use, phytochemistry and pharmacological profile of Piper longum thereby identifying research gaps and future opportunities for investigation on this plant.This systematic survey was accomplished as per the PRISMA guidelines. The information was collected from books, and electronic search (PubMed, Science Direct, Lilca and Scielo) during 1967–2019.Many phytochemicals have been identified till date, including alkaloids as its major secondary metabolites (piperine and piperlongumine), essential oil, flavonoids and steroids. These exhibit a wide range of activities including anti-inflammatory, analgesic, anti-oxidant, anti-microbial, anti-cancer, anti-parkinsonian, anti-stress, nootropic, anti-epileptic, anti-hyperglycemic, hepatoprotective, anti-hyperlipidemic, anti-platelet, anti-angiogenic, immunomodulatory, anti-arthritic, anti-ulcer, anti-asthmatic, anthelmintic action, anti-amebic, anti-fungal, mosquito larvicidal and anti-snake venom.Amongst various activities, bioscientific clarification in relation to its ethnopharmacological perspective has been evidenced mainly for anti-amebic, anthelminthic, anti-tumor and as contraceptive and hypoglycemic herb. However, despite traditional claims, insufficient scientific validation for the treatment of insomnia, dementia, epilepsy, rheumatoid arthritis, asthma, spleen disorder, puerperal fever and leprosy, necessitate future investigations in this direction. It is also essential and critical to generate toxicological data and pharmacokinetics on human subjects so as to confirm its conceivable bio-active components in the body. |
| ArticleNumber | 112255 |
| Author | Krishnan, Anuja Vohora, Divya Yadav, Vaishali |
| Author_xml | – sequence: 1 givenname: Vaishali surname: Yadav fullname: Yadav, Vaishali email: vaishali.yadav.phe13@itbhu.ac.in organization: Neurobehavioral Pharmacology Laboratory, Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India – sequence: 2 givenname: Anuja surname: Krishnan fullname: Krishnan, Anuja email: anuja.krishnan@jamiahamdard.ac.in organization: Department of Molecular Medicine, School of Interdisciplinary Science and Technology, Jamia Hamdard, New Delhi, 110062, India – sequence: 3 givenname: Divya surname: Vohora fullname: Vohora, Divya email: divyavohora@hotmail.com, dvohra@jamiahamdard.ac.in organization: Neurobehavioral Pharmacology Laboratory, Department of Pharmacology, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, 110062, India |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/31568819$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.5530/pj.2015.1.1 10.1016/S1995-7645(11)60048-5 10.3389/fimmu.2016.00175 10.1016/0031-9422(75)83139-6 10.1046/j.1469-8137.2000.00667.x 10.3390/medicines5030093 10.1080/0972060X.2015.1119065 10.1021/acs.jafc.7b05830 10.4103/0250-474X.57300 10.4103/0975-9476.65073 10.4103/0253-7613.41040 10.1002/slct.201702682 10.1080/10412905.2000.9712168 10.3389/fmicb.2018.01639 10.3923/jbs.2007.161.168 10.17660/ActaHortic.1999.501.47 10.2307/2804687 10.3923/ijp.2012.192.197 10.1038/sj.bjp.0706040 10.1111/j.1750-3841.2009.01401.x 10.1016/j.foodchem.2015.01.033 10.1111/jre.12518 10.1039/b514045p 10.3389/fphar.2017.00656 10.1016/j.jnutbio.2007.11.003 10.3923/rjmp.2011.352.376 10.1365/s10337-007-0408-2 10.3389/fphys.2016.00047 10.1016/j.phymed.2004.01.009 10.1089/act.2018.29201.eya 10.1016/j.jep.2006.06.004 10.1016/j.exppara.2009.08.002 10.1007/s13659-013-0073-0 10.1021/jf011708f 10.1016/j.fitote.2014.05.005 10.5214/ans.0972.7531.2010.170105 10.1002/ijc.10398 10.1039/C4RA12875C 10.1002/ptr.1014 10.1002/jps.2600751215 10.1016/j.jep.2013.03.022 10.1016/j.psep.2016.02.007 10.1016/j.jep.2011.06.046 10.1076/phbi.39.5.391.5893 10.5455/jice.20150921010411 10.1002/ptr.2630 10.1136/thorax.55.11.925 10.1016/j.cyto.2019.01.001 10.1016/S0378-8741(00)00354-8 10.1371/journal.pone.0113250 10.1007/s10493-016-0046-1 10.1007/s13273-010-0040-3 10.1271/bbb.100221 10.1007/s10493-017-0113-2 10.1016/j.prp.2015.11.012 10.3923/ijp.2007.400.405 10.3892/ol.2015.3459 10.1016/j.phymed.2007.06.011 10.1016/j.fitote.2012.12.001 10.1007/s12088-012-0303-x 10.3923/ijbc.2009.119.125 10.3109/13880209.2012.654395 10.17348/era.4.0.223-231 10.1021/jf061402e 10.1016/j.jtcme.2017.07.002 10.1016/0378-8741(92)90067-2 10.1007/s11101-006-9058-5 10.1016/0378-8741(96)01382-7 10.1039/c3an00016h 10.1038/s41564-019-0376-y 10.1371/journal.pone.0094298 10.1016/S0040-4039(01)99798-9 10.3390/ijms18071412 10.1111/jphp.12661 10.1007/s13277-016-4792-9 10.1016/j.etap.2013.09.002 10.1007/s00894-012-1508-y 10.1016/j.neuint.2015.06.004 10.1016/j.phymed.2007.06.007 10.1016/S0040-4020(01)82575-8 10.2174/1573407211666150915214425 10.1248/bpb.30.1221 10.1007/s11906-017-0775-5 10.1055/s-0031-1298537 10.3109/13880209.2014.991835 10.1080/14786410500045465 10.1016/j.nurt.2008.12.004 10.3390/ijms10083400 10.1076/phbi.39.3.236.5926 10.1016/j.jep.2004.01.014 10.1016/j.intimp.2005.10.013 10.1016/j.chroma.2004.03.056 10.1166/jnn.2015.8889 10.1002/jbt.22002 10.1016/j.ejphar.2010.05.026 10.1186/s12906-016-1392-6 10.5012/bkcs.2010.31.04.921 10.1056/NEJMra1004965 10.1016/j.biopha.2017.05.137 10.1021/jf102087c 10.1007/s11046-016-0057-9 10.1016/j.idc.2018.10.001 10.1016/j.yebeh.2015.05.012 10.3390/medicines3040025 10.1080/14786419.2014.981812 10.1016/S0305-1978(00)00083-1 10.1142/S0192415X17500021 10.1186/1472-6882-13-37 10.1016/j.jep.2003.10.016 10.1002/jcb.28311 10.1016/0031-9422(88)80226-7 10.1038/nrclinonc.2016.25 10.1089/acm.1999.5.81 10.1517/14656566.2013.815725 10.2202/1553-3840.1591 10.1080/10286020.2010.546789 10.1016/j.bjp.2016.06.005 10.3109/13880208009065171 10.1371/journal.pone.0171267 10.1021/bi050941u 10.4103/0974-8520.105258 10.1016/S0031-9422(98)00208-8 10.1080/09637480500146606 10.1007/s10493-018-0268-5 10.1007/s11418-013-0773-0 10.4103/2229-516X.81972 10.5530/pj.2018.2.57 10.1016/j.jep.2014.03.023 10.1016/j.msec.2013.08.039 10.1055/s-0028-1084242 |
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| Issue | NA |
| Keywords | Piper longum Pharmacology Traditional evidence Phytochemistry |
| Language | English |
| License | Copyright © 2019 Elsevier B.V. All rights reserved. |
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| References | Jin, Kanthasamy, Anantharam, Kanthasamy (bib60) 2019 Mallikarjuna, Narasimha, Sushma, Dillip, Reddy, Sreedhar, Raju (bib94) 2015; 15 Chaudhury, Chandrasekaran, Mishra (bib22) 2001; 74 González-Lamothe, Mitchell, Gattuso, Diarra, Malouin, Bouarab (bib48) 2009; 10 Huntley, Ernst (bib55) 2000; 55 Wiart (bib174) 2013 Ye, Jia, Ji, Sanders, Xue, Ji, Mason, Jiang (bib181) 2015; 10 Lin, Fu, Tsai, Cheng, Weng (bib88) 2017; 18 Liu, Jiang, Chen, Zhang, Ma (bib91) 2009; 34 Sarwar, Sharma, Arif, Thakur, Athar, Khillare, Thakur (bib132) 2014; 2 Foyer, Noctor (bib40) 2000; 146 Ramawat, Goyal (bib124) 2008 Schachter (bib135) 2009; 6 Srivastav, Fatima, Mondal (bib151) 2017; 92 Yarnell, Zimmerman (bib180) 2017; 25 Huang, Lan, Liu, Wang, Chen, Jin, Mou (bib53) 2015; 8 McInnes, Schett (bib99) 2011; 365 Nile, Keum, Nile, Jalde, Patel (bib109) 2018; 32 Dhifi, Bellili, Jazi, Bahloul, Mnif (bib36) 2016; 3 Chaveerach, Mokkamul, Sudmoon, Tanee (bib23) 2006; 4 Shenoy, Nipate, Sonpetkar, Salvi, Waghmare, Chaudhari (bib141) 2013; 147 Warrell (bib173) 2019; 33 Chaudhary, Mukherjee, Maiti, De, Bhadra, Saha (bib21) 2013; 12 Park, Son, Park, Kim, Lee (bib115) 2007; 14 Barua, Singh, Sen, Barua, Barua (bib13) 2014; 1 Ghosal, Deb, Mishra, Vishwakarma (bib43) 2012; 78 Iwashita, Saito, Yamaguchi, Takagaki, Nakahata (bib56) 2007; 30 Koorse, Samraj, John, Narayanan, Devi, Usha, Sunilkumar, Gleeja (bib74) 2018; 10 Srivastava, Srivastava, Pandey, Khanna, Pant (bib152) 2019 Juvekar, Kulkarni, Juvekar (bib64) 2008; 74 Sarwar, Nirala, Arif, Khillare, Thakur (bib133) 2015; 29 Randhawa, Jagdev Singh Kullar (bib125) 2011; 1 Bae, Kim, Jung, Seo, Yun, Kim, Park, Kim, Song, Park (bib10) 2010; 642 Jeon, Bose, Hur, Jun, Kim, Cho, Koo (bib58) 2011; 137 Wang, Koyama, Liu, Xu, Ma, Liang, Kim, Brenner, Kisseleva (bib172) 2016; 7 Yang, Su, Luo, Gu, Niu, Li, Wang, Long (bib177) 2013; 3 Singh, Saini, Singh, Sharma, Rath (bib144) 2017; 71 Song, Nie, Li, Du (bib149) 2016; 212 Nath, Banerjee (bib108) 2013; 36 Sahi, Tewatia, Ghosal (bib128) 2012; 18 Yadav, Chatterjee, Majeed, Kumar (bib176) 2015; 4 Choudhary (bib26) 2006; 20 Dalby (bib32) 2002 Duan, Zhang, Deng, Cao, Zhou, Wu, Chen, Shen, Xu, Zhang, Duan (bib38) 2016; 37 Lakshmi, Kumar, Agarwal, Dhar (bib83) 2006; 20 Nakada-Tsukui, Nozaki (bib105) 2016; 7 Singh, Kumar, Tandan, Mishra (bib147) 2009; 123 Scott, Jensen, Philogène, Arnason (bib136) 2008; 7 Christina, Saraswathy, Robert, Kothai, Chidambaranathan, Nalini, Therasal (bib28) 2006; 13 Kumar, Anilakumar, Naveen (bib78) 2015; 7 Kaefer, Milner (bib65) 2008; 19 Huang, Morgan, Asolkar, Koivunen, Marrone (bib54) 2010; 58 Lee, Park, Huh, Lee, Yum (bib86) 2010; 6 Nasrollahzadeh, Sajadi, Maham, Ehsani (bib107) 2015; 5 Ohno, Watabe, Nakamura, Kawagoshi, Uotsu, Chiba, Yamada, Yamaguchi, Yamada, Miyamoto (bib112) 2010; 74 Campana, Iredale (bib18) 2017 Chatterjee, Dutta (bib20) 1967; 23 Mishra, Sinha, Guru, Bhushan, Vishwakarma, Ghosal (bib101) 2011; 13 Godara, Verma, Katoch, Yadav, Dutt, Satti, Katoch (bib46) 2018; 75 Zhang, Chen, Wang, Wu (bib185) 1996; 18 Varughese, Unnikrishnan, Deepak, Balachandran, Rema Shree (bib168) 2016; 19 Singh, Kumar, Tandan (bib146) 2008; 40 Ghoshal, Prasad, Lakshmi (bib45) 1996; 50 Nor, Huda, Othman, Tohit, Rahayu, Md Noor (bib111) 2016 Tebbs (bib159) 1993 Sawangjaroen, Sawangjaroen, Poonpanang (bib134) 2004; 91 Bhutani, Singh, Bharate, Singh (bib15) 2007; 46 Wakade, Shah, Kulkarni, Juvekar (bib170) 2008; 46 Bancroft, Chen, Yeh, Sunwoo, Yeh, Jackson, Jackson, Van Waes (bib9) 2002; 99 Thomas, Sujatha, George (bib161) 2009; 47 Evans (bib39) 2009 Nakkala, Mata, Sadras (bib106) 2016; 100 Chrysant, Chrysant (bib29) 2017; 19 Kaushik, Rani, Kaushik, Sacher, Yadav (bib67) 2012; 8 Khalil, Smith, Brentjens, Wolchok (bib68) 2016; 13 Madhusudhan, Vandana (bib93) 2001; 29 Srivastava (bib153) 2014; 4 Abdubakiev, Li, Lu, Li, Aisa (bib1) 2019; 1–4 Reddy, Vali, Rani, Rani (bib126) 2014; 34 Prassanna, Naika, Ganapathy (bib121) 2011; 2 Saraf, Saraf (bib131) 2014; 6 McGee (bib98) 2004 Wal, Wal, Rai, Tiwari, Prajapati (bib171) 2019 Chatterjee, Dutta (bib19) 1966; 16 Jin, Borjihan, Zhao, Sun, Hammond, Uryu (bib192) 2009; 23 Harwansh, Mukherjee, Bhadra, Kar, Bahadur, Mitra, Mukherjee (bib51) 2014; 153 Krishna, Joy, Sundaresan (bib76) 2015; 52 Ghoshal, Lakshmi (bib44) 2002; 16 Mouhajir, Pedersen, Rejdali, Towers (bib102) 2001; 39 Dasgupta, Datta (bib34) 1980; 18 Shankaracharya, Jaganmohan Rao, Pura Naik, Nagalakshmi (bib137) 1997; 34 Parmar, Jain, Gupta, Talwar, Rajwanshi, Kumar, Azim, Malhotra, Kumar, Jain (bib117) 1998; 49 Ramesh, Hari, Pandian, Arumugam (bib187) 2011; 8 Tewtrakul, Hase, Kadota, Namba, Komatsu, Tanaka (bib160) 2000; 12 Kamboj (bib66) 2000; 78 Liu, Luo, Chen, Ba, Zheng, Guo, Wu (bib89) 2015; 177 Bi, Qu, Wang, Zheng, Liu, Luo, Chen, Ba, Wu, Yang (bib16) 2015; 53 Dai, Zhang, Williams, Yuan, Wang (bib31) 2017; 45 Rahman, Beg, Verma, Al Abbasi, Anwar, Saini, Akhter, Kumar (bib123) 2017; 69 Cheng, Wu, Huang, Pang, Huang, Cheng (bib24) 2019; 116 Khare (bib70) 2008 Li, Niu, Dong, Gao, Zhang, Zheng, Shi, Liu, Li (bib87) 2019 Ovadje, Ma, Tremblay, Roma, Steckle, Guerrero, Arnason, Pandey (bib113) 2014; 9 Joseph, Jini (bib62) 2011; 5 Madhu, Vijayan, Shaukath (bib92) 2011; 4 Arambewela, Wijesundera, R.L.C. (bib6) 1999; 501 Desai, Prabhu, Mulchandani (bib35) 1988; 27 Khushbu, Roshni, Anar, Carol, Mayuree (bib71) 2011; 2 Ullah, Rehman, Zafeer, Rehman, Khan, Khan, Khan, Khan, Abidi (bib163) 2017; 12 Bhuiyan, Begum, Anwar (bib14) 2008; 77–85 Sunila, Kuttan (bib156) 2004; 90 Fofaria, Kim, Srivastava (bib41) 2014; 9 Saleem, Kim, Ali, Lee (bib129) 2005; 22 Siqueira-Lima, Silva, Quintans, Antoniolli, Shanmugam, Barreto, Santos, Almeida, Bonjardim, Menezes (bib148) 2017; 27 Sunila, Kuttan (bib157) 2006; 6 Pandey, Singh (bib118) 2009; 47 Pullela, Tiwari, Vanka, Vummenthula, Tatipaka, Dasari, Khan, Janaswamy (bib122) 2006; 108 Sharma, Kumar, Chashoo, Saxena, Pandey (bib139) 2014; 51 Johri, Zutshi (bib61) 1992; 37 Özdemir, Bildziukevich, Wimmerová, Macůrková, Lovecká, Wimmer (bib114) 2018; 3 Subburaman, Sampath, Janardhanam (bib154) 2010; 17 He, Guo, Xu, Chen, Zhang, Wu, Wang (bib52) 2016; 16 Chinta, Syed, Coumar, Periyasamy (bib25) 2015; 11 Jagdale, Kuchekar, Chabukswar, Lokhande, Raut (bib57) 2009; 3 Rouhi-Boroujeni, Rouhi-Boroujeni, Heidarian, Mohammadizadeh, Rafieian-Kopaei (bib127) 2015; 11 Manoharan, Silvan, Vasudevan, Balakrishnan (bib95) 2007; 6 Wu, Sun, Pei, Lu, Pan (bib175) 2004; 1040 Yende, Sannapuri, Vyawahare, Harle (bib182) 2010; 1 McNamara, Randall, Gunthorpe (bib100) 2005; 144 Sharma, Nehru (bib140) 2015; 87 Aneja, Joshi, Sharma, Aneja (bib5) 2010; 9 Kokate, Chaudhari, Nimbkar (bib73) 1980 Sucher, Carles (bib155) 2015; 52 Khan, Siddiqui (bib69) 2007; 6 Kumar, Arya, Mukherjee, Singh, Singh, Parmar, Prasad, Ghosh (bib79) 2005; 44 Liu, Song, Hu (bib90) 2007; 66 Nabi, Kasetti, Sirasanagandla, Tilak, Kumar, Rao (bib104) 2013; 13 Gaur, Sangwan, Sangwan, Kumar (bib42) 2016; 69 Nonaka, Kajiura, Bando, Sakamoto, Inagaki, Lew, Naruishi, Ikuta, Yoshida, Kobayashi (bib110) 2018; 53 Latief, Ahmad (bib82) 2018; 8 Joshi (bib63) 1944 Shanker, Jassal, Rani, Kaith (bib138) 2016; 96 Bajpai, Pande, Tewari, Prakash (bib8) 2005; 56 Dutta, Banerjee, Roy (bib37) 1975; 14 Das, Jha, Policegoudra, Mazumder, Das, Chattopadhyay, Singh (bib33) 2012; 52 Gulati, Anand, Ray (bib50) 2016 Kilari, Rao, Sreemanthula, Kola (bib72) 2015; 13 Utpala, Asish, Saji, George, Leela, Mathew (bib164) 2014; 23 Kumar, Sharma, Vasudeva (bib80) 2013; 14 Vedhanayaki, Shastri, Kuruvilla (bib169) 2003; 41 Yang, Lee, Lee, Kim, Lee, Lee (bib178) 2002; 50 Tungmunnithum, Thongboonyou, Pholboon, Yangsabai (bib162) 2018; 5 Rajeswary, Vasuki, Samudram, Geetha (bib188) 2011; 49 Zheng, Wang, Ba, Liu, Wang, Guo, Wu, Yang (bib186) 2014; 39 Lee, Rho, Park, Choi, Kang, Lee, Kim, Lee, Kim (bib85) 2006; 54 United States Department of Agriculture, Natural Resources Conservation Service (bib165) Jiang, Liu, Huang, Huang (bib59) 2013; 84 Atal, Bedi (bib7) 2010; 1 Bao, Ochir, Sun, Borjihan, Yamagishi (bib12) 2014; 68 Shoji, Umeyama, Saito, Takemoto, Kajiwara, Ohizumi (bib142) 1986; 75 Bao, Bai, Borijihan (bib11) 2012; 50 Lee, Kim, Park, Park, Lee, Chang, Rho (bib84) 2010; 31 Choudhary, Singh (bib27) 2017 Valentynivna (bib167) 2017; 11 Samudram, Vasuki, Rajeshwari, Geetha, Moorthi (bib130) 2009; 3 Martinez-Rossi, Peres, Rossi (bib97) 2017; 182 Parker-Cote, Meggs (bib116) 2018; 3 Kumari, Ashok, Ravishankar, Pandya, Acharya (bib81) 2012; 33 Peter (bib119) 2006; vol. 3 Yuncker (bib183) 1958; 10 Agrawal, Rao, Sairam, Joshi, Goel (bib2) 2000; 38 Ali, Alam, Yeasmin, Khan, Sayeed, Rao (bib4) 2007; 3 Li, Zhu, Fu, Ke, Jin, Liang (bib193) 2013; 138 D'Cruz, Nimbkark, Kokate (bib30) 1980; 17 Yang, Ho, Zhang, Wan, Zhang, Lim (bib179) 2018; 66 Mustafa, Hamid, Mohamed, Bakar (bib103) 2010; 75 Pradhan, Suri, Pradhan, Biswasroy (bib120) 2013; 1 Taghizadeh, Mardani, Rostami, Taghizadeh, Bazireh, Hayat (bib158) 2019; 120 Gonelimali, Lin, Miao, Xuan, Charles, Chen, Hatab (bib47) 2018; 9 Manyam (bib96) 1999; 5 Cabandugama, Gardner, Sowers (bib17) 2017; 101 Vaghasiya, Nair, Chanda (bib166) 2007; 3 Kraemer, Reiner, Brady, Messina, Gilbert, Pigott, Yi, Johnson, Earl, Marczak (bib75) 2019; 4 Kumar, Panghal, Mallapur, Kumar, Ram, Singh (bib77) 2009; 71 Alexander, Qureshi, Kumari, Vaishnav, Sharma, Saraf, Saraf (bib3) 2014; 97 Singh, Kumar, Gupta, Tandan (bib145) 2007; 21 Zaveri, Khandhar, Patel, Patel (bib184) 2010; 5 Singh, Kumar, Singh, Raj, Prasad, Parmar, Ghosh (bib143) 2008; 15 Goyal, Prajapati, Gore, Patil, Mahajan, Sharma, Talla, Ojha (bib49) 2017; 8 Srinivasa Reddy, Jamil, Madhusudhan, Anjani, Das (bib150) 2001; 39 Varughese (10.1016/j.jep.2019.112255_bib168) 2016; 19 Khushbu (10.1016/j.jep.2019.112255_bib71) 2011; 2 Christina (10.1016/j.jep.2019.112255_bib28) 2006; 13 Rahman (10.1016/j.jep.2019.112255_bib123) 2017; 69 Singh (10.1016/j.jep.2019.112255_bib147) 2009; 123 Jagdale (10.1016/j.jep.2019.112255_bib57) 2009; 3 Peter (10.1016/j.jep.2019.112255_bib119) 2006; vol. 3 United States Department of Agriculture (10.1016/j.jep.2019.112255_bib165) Foyer (10.1016/j.jep.2019.112255_bib40) 2000; 146 Nakada-Tsukui (10.1016/j.jep.2019.112255_bib105) 2016; 7 Kaefer (10.1016/j.jep.2019.112255_bib65) 2008; 19 Lee (10.1016/j.jep.2019.112255_bib84) 2010; 31 Nonaka (10.1016/j.jep.2019.112255_bib110) 2018; 53 Choudhary (10.1016/j.jep.2019.112255_bib27) 2017 Reddy (10.1016/j.jep.2019.112255_bib126) 2014; 34 Sawangjaroen (10.1016/j.jep.2019.112255_bib134) 2004; 91 Lin (10.1016/j.jep.2019.112255_bib88) 2017; 18 Bao (10.1016/j.jep.2019.112255_bib12) 2014; 68 Choudhary (10.1016/j.jep.2019.112255_bib26) 2006; 20 Chrysant (10.1016/j.jep.2019.112255_bib29) 2017; 19 Wakade (10.1016/j.jep.2019.112255_bib170) 2008; 46 Yang (10.1016/j.jep.2019.112255_bib178) 2002; 50 Parmar (10.1016/j.jep.2019.112255_bib117) 1998; 49 Kumar (10.1016/j.jep.2019.112255_bib80) 2013; 14 Srivastava (10.1016/j.jep.2019.112255_bib152) 2019 Lee (10.1016/j.jep.2019.112255_bib85) 2006; 54 Sharma (10.1016/j.jep.2019.112255_bib139) 2014; 51 Huang (10.1016/j.jep.2019.112255_bib54) 2010; 58 Ramesh (10.1016/j.jep.2019.112255_bib187) 2011; 8 Thomas (10.1016/j.jep.2019.112255_bib161) 2009; 47 Zhang (10.1016/j.jep.2019.112255_bib185) 1996; 18 Ghoshal (10.1016/j.jep.2019.112255_bib44) 2002; 16 Huang (10.1016/j.jep.2019.112255_bib53) 2015; 8 González-Lamothe (10.1016/j.jep.2019.112255_bib48) 2009; 10 Harwansh (10.1016/j.jep.2019.112255_bib51) 2014; 153 Johri (10.1016/j.jep.2019.112255_bib61) 1992; 37 Bajpai (10.1016/j.jep.2019.112255_bib8) 2005; 56 Juvekar (10.1016/j.jep.2019.112255_bib64) 2008; 74 Ye (10.1016/j.jep.2019.112255_bib181) 2015; 10 Yende (10.1016/j.jep.2019.112255_bib182) 2010; 1 Bae (10.1016/j.jep.2019.112255_bib10) 2010; 642 Gaur (10.1016/j.jep.2019.112255_bib42) 2016; 69 Krishna (10.1016/j.jep.2019.112255_bib76) 2015; 52 Nath (10.1016/j.jep.2019.112255_bib108) 2013; 36 Bhuiyan (10.1016/j.jep.2019.112255_bib14) 2008; 77–85 Mallikarjuna (10.1016/j.jep.2019.112255_bib94) 2015; 15 Pullela (10.1016/j.jep.2019.112255_bib122) 2006; 108 Mustafa (10.1016/j.jep.2019.112255_bib103) 2010; 75 Dhifi (10.1016/j.jep.2019.112255_bib36) 2016; 3 Kokate (10.1016/j.jep.2019.112255_bib73) 1980 Nakkala (10.1016/j.jep.2019.112255_bib106) 2016; 100 Kilari (10.1016/j.jep.2019.112255_bib72) 2015; 13 Jin (10.1016/j.jep.2019.112255_bib60) 2019 Kumar (10.1016/j.jep.2019.112255_bib79) 2005; 44 Sarwar (10.1016/j.jep.2019.112255_bib133) 2015; 29 Lee (10.1016/j.jep.2019.112255_bib86) 2010; 6 Shoji (10.1016/j.jep.2019.112255_bib142) 1986; 75 Wang (10.1016/j.jep.2019.112255_bib172) 2016; 7 Srivastav (10.1016/j.jep.2019.112255_bib151) 2017; 92 Goyal (10.1016/j.jep.2019.112255_bib49) 2017; 8 Ullah (10.1016/j.jep.2019.112255_bib163) 2017; 12 McGee (10.1016/j.jep.2019.112255_bib98) 2004 Sucher (10.1016/j.jep.2019.112255_bib155) 2015; 52 Gulati (10.1016/j.jep.2019.112255_bib50) 2016 Parker-Cote (10.1016/j.jep.2019.112255_bib116) 2018; 3 Kraemer (10.1016/j.jep.2019.112255_bib75) 2019; 4 Manyam (10.1016/j.jep.2019.112255_bib96) 1999; 5 Lakshmi (10.1016/j.jep.2019.112255_bib83) 2006; 20 Ovadje (10.1016/j.jep.2019.112255_bib113) 2014; 9 Chatterjee (10.1016/j.jep.2019.112255_bib20) 1967; 23 Liu (10.1016/j.jep.2019.112255_bib91) 2009; 34 Ramawat (10.1016/j.jep.2019.112255_bib124) 2008 Chaveerach (10.1016/j.jep.2019.112255_bib23) 2006; 4 Nor (10.1016/j.jep.2019.112255_bib111) 2016 Saleem (10.1016/j.jep.2019.112255_bib129) 2005; 22 Randhawa (10.1016/j.jep.2019.112255_bib125) 2011; 1 Agrawal (10.1016/j.jep.2019.112255_bib2) 2000; 38 Dalby (10.1016/j.jep.2019.112255_bib32) 2002 Duan (10.1016/j.jep.2019.112255_bib38) 2016; 37 D'Cruz (10.1016/j.jep.2019.112255_bib30) 1980; 17 Nile (10.1016/j.jep.2019.112255_bib109) 2018; 32 Manoharan (10.1016/j.jep.2019.112255_bib95) 2007; 6 Gonelimali (10.1016/j.jep.2019.112255_bib47) 2018; 9 Sunila (10.1016/j.jep.2019.112255_bib157) 2006; 6 Saraf (10.1016/j.jep.2019.112255_bib131) 2014; 6 Ghosal (10.1016/j.jep.2019.112255_bib43) 2012; 78 Sarwar (10.1016/j.jep.2019.112255_bib132) 2014; 2 He (10.1016/j.jep.2019.112255_bib52) 2016; 16 Singh (10.1016/j.jep.2019.112255_bib145) 2007; 21 Rouhi-Boroujeni (10.1016/j.jep.2019.112255_bib127) 2015; 11 Prassanna (10.1016/j.jep.2019.112255_bib121) 2011; 2 Vaghasiya (10.1016/j.jep.2019.112255_bib166) 2007; 3 Yang (10.1016/j.jep.2019.112255_bib179) 2018; 66 Scott (10.1016/j.jep.2019.112255_bib136) 2008; 7 Wu (10.1016/j.jep.2019.112255_bib175) 2004; 1040 Liu (10.1016/j.jep.2019.112255_bib90) 2007; 66 Arambewela (10.1016/j.jep.2019.112255_bib6) 1999; 501 Warrell (10.1016/j.jep.2019.112255_bib173) 2019; 33 Latief (10.1016/j.jep.2019.112255_bib82) 2018; 8 Jeon (10.1016/j.jep.2019.112255_bib58) 2011; 137 Shanker (10.1016/j.jep.2019.112255_bib138) 2016; 96 Huntley (10.1016/j.jep.2019.112255_bib55) 2000; 55 Pradhan (10.1016/j.jep.2019.112255_bib120) 2013; 1 Joshi (10.1016/j.jep.2019.112255_bib63) 1944 Park (10.1016/j.jep.2019.112255_bib115) 2007; 14 Bhutani (10.1016/j.jep.2019.112255_bib15) 2007; 46 Chinta (10.1016/j.jep.2019.112255_bib25) 2015; 11 Godara (10.1016/j.jep.2019.112255_bib46) 2018; 75 Ohno (10.1016/j.jep.2019.112255_bib112) 2010; 74 Rajeswary (10.1016/j.jep.2019.112255_bib188) 2011; 49 Das (10.1016/j.jep.2019.112255_bib33) 2012; 52 Tebbs (10.1016/j.jep.2019.112255_bib159) 1993 Wal (10.1016/j.jep.2019.112255_bib171) 2019 Khan (10.1016/j.jep.2019.112255_bib69) 2007; 6 Subburaman (10.1016/j.jep.2019.112255_bib154) 2010; 17 Srivastava (10.1016/j.jep.2019.112255_bib153) 2014; 4 Singh (10.1016/j.jep.2019.112255_bib143) 2008; 15 Atal (10.1016/j.jep.2019.112255_bib7) 2010; 1 Song (10.1016/j.jep.2019.112255_bib149) 2016; 212 Bancroft (10.1016/j.jep.2019.112255_bib9) 2002; 99 Khalil (10.1016/j.jep.2019.112255_bib68) 2016; 13 Utpala (10.1016/j.jep.2019.112255_bib164) 2014; 23 Li (10.1016/j.jep.2019.112255_bib193) 2013; 138 Tewtrakul (10.1016/j.jep.2019.112255_bib160) 2000; 12 Tungmunnithum (10.1016/j.jep.2019.112255_bib162) 2018; 5 Alexander (10.1016/j.jep.2019.112255_bib3) 2014; 97 Cabandugama (10.1016/j.jep.2019.112255_bib17) 2017; 101 Chatterjee (10.1016/j.jep.2019.112255_bib19) 1966; 16 Chaudhury (10.1016/j.jep.2019.112255_bib22) 2001; 74 Fofaria (10.1016/j.jep.2019.112255_bib41) 2014; 9 Zheng (10.1016/j.jep.2019.112255_bib186) 2014; 39 Mouhajir (10.1016/j.jep.2019.112255_bib102) 2001; 39 Khare (10.1016/j.jep.2019.112255_bib70) 2008 Mishra (10.1016/j.jep.2019.112255_bib101) 2011; 13 Kumar (10.1016/j.jep.2019.112255_bib77) 2009; 71 Zaveri (10.1016/j.jep.2019.112255_bib184) 2010; 5 Ghoshal (10.1016/j.jep.2019.112255_bib45) 1996; 50 Barua (10.1016/j.jep.2019.112255_bib13) 2014; 1 Campana (10.1016/j.jep.2019.112255_bib18) 2017 Jin (10.1016/j.jep.2019.112255_bib192) 2009; 23 Wiart (10.1016/j.jep.2019.112255_bib174) 2013 Yang (10.1016/j.jep.2019.112255_bib177) 2013; 3 Cheng (10.1016/j.jep.2019.112255_bib24) 2019; 116 Desai (10.1016/j.jep.2019.112255_bib35) 1988; 27 Liu (10.1016/j.jep.2019.112255_bib89) 2015; 177 Singh (10.1016/j.jep.2019.112255_bib144) 2017; 71 Yadav (10.1016/j.jep.2019.112255_bib176) 2015; 4 Yuncker (10.1016/j.jep.2019.112255_bib183) 1958; 10 Abdubakiev (10.1016/j.jep.2019.112255_bib1) 2019; 1–4 Li (10.1016/j.jep.2019.112255_bib87) 2019 Evans (10.1016/j.jep.2019.112255_bib39) 2009 Samudram (10.1016/j.jep.2019.112255_bib130) 2009; 3 Kumari (10.1016/j.jep.2019.112255_bib81) 2012; 33 Bao (10.1016/j.jep.2019.112255_bib11) 2012; 50 Yarnell (10.1016/j.jep.2019.112255_bib180) 2017; 25 Kumar (10.1016/j.jep.2019.112255_bib78) 2015; 7 Taghizadeh (10.1016/j.jep.2019.112255_bib158) 2019; 120 Iwashita (10.1016/j.jep.2019.112255_bib56) 2007; 30 Jiang (10.1016/j.jep.2019.112255_bib59) 2013; 84 Martinez-Rossi (10.1016/j.jep.2019.112255_bib97) 2017; 182 Schachter (10.1016/j.jep.2019.112255_bib135) 2009; 6 Vedhanayaki (10.1016/j.jep.2019.112255_bib169) 2003; 41 Bi (10.1016/j.jep.2019.112255_bib16) 2015; 53 Özdemir (10.1016/j.jep.2019.112255_bib114) 2018; 3 Joseph (10.1016/j.jep.2019.112255_bib62) 2011; 5 McInnes (10.1016/j.jep.2019.112255_bib99) 2011; 365 Nabi (10.1016/j.jep.2019.112255_bib104) 2013; 13 Kaushik (10.1016/j.jep.2019.112255_bib67) 2012; 8 Sharma (10.1016/j.jep.2019.112255_bib140) 2015; 87 Sunila (10.1016/j.jep.2019.112255_bib156) 2004; 90 Shankaracharya (10.1016/j.jep.2019.112255_bib137) 1997; 34 Shenoy (10.1016/j.jep.2019.112255_bib141) 2013; 147 Madhu (10.1016/j.jep.2019.112255_bib92) 2011; 4 Dai (10.1016/j.jep.2019.112255_bib31) 2017; 45 Madhusudhan (10.1016/j.jep.2019.112255_bib93) 2001; 29 McNamara (10.1016/j.jep.2019.112255_bib100) 2005; 144 Chaudhary (10.1016/j.jep.2019.112255_bib21) 2013; 12 Sahi (10.1016/j.jep.2019.112255_bib128) 2012; 18 Nasrollahzadeh (10.1016/j.jep.2019.112255_bib107) 2015; 5 Aneja (10.1016/j.jep.2019.112255_bib5) 2010; 9 Dutta (10.1016/j.jep.2019.112255_bib37) 1975; 14 Srinivasa Reddy (10.1016/j.jep.2019.112255_bib150) 2001; 39 Ali (10.1016/j.jep.2019.112255_bib4) 2007; 3 Singh (10.1016/j.jep.2019.112255_bib146) 2008; 40 Siqueira-Lima (10.1016/j.jep.2019.112255_bib148) 2017; 27 Valentynivna (10.1016/j.jep.2019.112255_bib167) 2017; 11 Koorse (10.1016/j.jep.2019.112255_bib74) 2018; 10 Pandey (10.1016/j.jep.2019.112255_bib118) 2009; 47 Dasgupta (10.1016/j.jep.2019.112255_bib34) 1980; 18 Kamboj (10.1016/j.jep.2019.112255_bib66) 2000; 78 |
| References_xml | – year: 2009 ident: bib39 article-title: Trease and Evans' Pharmacognosy – volume: 1 start-page: 96 year: 2010 ident: bib7 article-title: Bioenhancers: revolutionary concept to market publication-title: J. Ayurveda Integr. Med. – volume: 11 start-page: 156 year: 2015 end-page: 169 ident: bib25 article-title: Piperine: a comprehensive review of pre-clinical and clinical investigations publication-title: Curr. Bioact. Compd. – volume: 66 start-page: 785 year: 2007 end-page: 790 ident: bib90 article-title: GC–MS analysis of the essential oils of piper nigrum L. And piper longum L publication-title: Chromatographia – volume: 3 start-page: 277 year: 2013 end-page: 281 ident: bib177 article-title: New amide alkaloids from Piper longum fruits publication-title: Nat. Prod. Bioprospect – volume: 29 start-page: 1166 year: 2015 end-page: 1169 ident: bib133 article-title: Spermicidal activity of the hexane extract of Piper longum: an in vitro study publication-title: Nat. Prod. Rep. – volume: 23 start-page: 1769 year: 1967 end-page: 1781 ident: bib20 article-title: Alkaloids of Piper longum Linn—I: structure and synthesis of piperlongumine and piperlonguminine publication-title: Tetrahedron – volume: 116 start-page: 48 year: 2019 end-page: 60 ident: bib24 article-title: Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells publication-title: Cytokine – volume: 146 start-page: 359 year: 2000 end-page: 388 ident: bib40 article-title: Tansley Review No. 112 Oxygen processing in photosynthesis: regulation and signalling publication-title: New Phytol. – volume: 4 start-page: 854 year: 2019 end-page: 863 ident: bib75 article-title: Past and future spread of the arbovirus vectors Aedes aegypti and Aedes albopictus publication-title: Nat. Microbiol. – volume: 49 start-page: 1069 year: 1998 end-page: 1078 ident: bib117 article-title: Polyphenols and alkaloids from Piper species publication-title: Phytochemistry – volume: 71 start-page: 303 year: 2017 end-page: 317 ident: bib144 article-title: In vitro assessment of the acaricidal activity of Piper longum, Piper nigrum, and Zingiber officinale extracts against Hyalomma anatolicum ticks publication-title: Exp. Appl. Acarol. – volume: 9 year: 2014 ident: bib41 article-title: Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation publication-title: PLoS One – volume: 36 start-page: 997 year: 2013 end-page: 1014 ident: bib108 article-title: Green nanotechnology–a new hope for medical biology publication-title: Environ. Toxicol. Pharmacol. – volume: 14 start-page: 853 year: 2007 end-page: 855 ident: bib115 article-title: Antiplatelet effects of acidamides isolated from the fruits of Piper longum L publication-title: Phytomedicine – volume: 75 start-page: 333 year: 2018 end-page: 343 ident: bib46 article-title: In vitro acaricidal activity of Piper nigrum and Piper longum fruit extracts and their active components against Rhipicephalus (Boophilus) microplus ticks publication-title: Exp. Appl. Acarol. – volume: 3 start-page: 2196 year: 2018 end-page: 2214 ident: bib114 article-title: Plant adaptogens: natural medicaments for 21st century? publication-title: ChemistrySelect – volume: 68 start-page: 211 year: 2014 end-page: 214 ident: bib12 article-title: Occurrence of piperidine alkaloids in Piper species collected in different areas publication-title: J. Nat. Med. – volume: 69 start-page: 487 year: 2016 end-page: 500 ident: bib42 article-title: Acaricide resistance in Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum collected from Haryana and Rajasthan states of India publication-title: Exp. Appl. Acarol. – volume: 6 start-page: 161 year: 2007 end-page: 168 ident: bib95 article-title: Antihyperglycemic and antilipidperoxidative effects of Piper longum (Linn.) dried fruits in alloxan induced diabetic rats publication-title: J. Biol. Sci. – volume: 6 start-page: 733 year: 2006 end-page: 741 ident: bib157 article-title: Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice publication-title: Int. Immunopharmacol. – volume: 87 start-page: 92 year: 2015 end-page: 105 ident: bib140 article-title: Characterization of the lipopolysaccharide induced model of Parkinson's disease: role of oxidative stress and neuroinflammation publication-title: Neurochem. Int. – volume: 10 start-page: 1 year: 1958 end-page: 7 ident: bib183 article-title: The Piperaceae—a family profile publication-title: Brittonia – volume: 3 start-page: 119 year: 2009 end-page: 125 ident: bib57 article-title: Anti-oxidant activity of piper longum linn publication-title: Int. J. Biol. Chem. – volume: 39 start-page: 1660 year: 2014 end-page: 1665 ident: bib186 article-title: Protective effect of alkaloids from Piper longum in rat dopaminergic neuron injury of 6-OHDA-induced Parkinson's disease publication-title: Zhongguo Zhongyao Zazhi – volume: 92 start-page: 856 year: 2017 end-page: 863 ident: bib151 article-title: Important medicinal herbs in Parkinson's disease pharmacotherapy publication-title: Biomed. Pharmacother. – volume: 15 start-page: 1280 year: 2015 end-page: 1286 ident: bib94 article-title: Biogenic preparation of gold nanostructures reduced from Piper longum leaf broth and their electrochemical studies publication-title: J. Nanosci. Nanotechnol. – volume: 1 start-page: 5 year: 2011 ident: bib125 article-title: Bioenhancers from mother nature and their applicability in modern medicine publication-title: Int. J. Appl. Basic. Med. Res. – volume: 30 start-page: 1221 year: 2007 end-page: 1225 ident: bib56 article-title: Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A2 receptor publication-title: Biol. Pharm. Bull. – volume: 14 start-page: 2090 year: 1975 end-page: 2091 ident: bib37 article-title: Lignans in the seeds of Piper longum publication-title: Phytochemistry – volume: 1 start-page: 147 year: 2013 end-page: 167 ident: bib120 article-title: Golden heart of the nature: piper betle L publication-title: J. Pharmacogn. Phytochem. – volume: 34 start-page: 2891 year: 2009 end-page: 2894 ident: bib91 article-title: Chemical constituents from Piper longum publication-title: Zhongguo Zhongyao Zazhi – volume: 1–4 year: 2019 ident: bib1 article-title: N-Alkylamides from Piper longum L. and their stimulative effects on the melanin content and tyrosinase activity in B16 melanoma cells publication-title: Nat. Prod. Res. – volume: 91 start-page: 357 year: 2004 end-page: 360 ident: bib134 article-title: Effects of Piper longum fruit, Piper sarmentosum root and Quercus infectoria nut gall on caecal amoebiasis in mice publication-title: J. Ethnopharmacol. – volume: 6 start-page: 111 year: 2007 end-page: 113 ident: bib69 article-title: Antimicrobial activity of Piper fruits publication-title: IJNPR – volume: 108 start-page: 445 year: 2006 end-page: 449 ident: bib122 article-title: HPLC assisted chemobiological standardization of α-glucosidase-I enzyme inhibitory constituents from Piper longum Linn-An Indian medicinal plant publication-title: J. Ethnopharmacol. – volume: 49 start-page: 276 year: 2011 end-page: 281 ident: bib188 article-title: Hepatoprotective action of ethanolic extracts of Melia azedarach Linn. and Piper longum Linn and their combination on CCl4 induced hepatotoxicity in rats publication-title: Indian J. Exp. Biol. – volume: 47 start-page: 643 year: 2009 end-page: 648 ident: bib118 article-title: Molluscicidal activity of piper cubeba linn., piper longum linn. And tribulus terrestris linn. and their combinations against snail indoplanorbis exustus desh publication-title: Indian J. Exp. Biol. – volume: 8 start-page: 656 year: 2017 ident: bib49 article-title: Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin publication-title: Front. Pharmacol. – volume: 52 start-page: 3561 year: 2015 end-page: 3570 ident: bib76 article-title: Effect on oxidative stress, glucose uptake level and lipid droplet content by Apigenin 7, 4'-dimethyl ether isolated from Piper longum L publication-title: J. Food Sci. Technol. – volume: 120 start-page: 8891 year: 2019 end-page: 8898 ident: bib158 article-title: Molecular mechanisms, prevalence, and molecular methods for familial combined hyperlipidemia disease: a review publication-title: J. Cell. Biochem. – volume: 54 start-page: 9759 year: 2006 end-page: 9763 ident: bib85 article-title: Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum publication-title: J. Agric. Food Chem. – volume: 29 start-page: 537 year: 2001 end-page: 538 ident: bib93 article-title: Tetrahydropiperine, the first natural aryl pentanamide from Piper longum publication-title: Biochem. Syst. Ecol. – volume: 11 start-page: 1 year: 2017 end-page: 6 ident: bib167 article-title: Scientific justification of anthelmintic medicines based on medicinal plant material. I.J.G.P. – volume: 9 start-page: 421 year: 2010 end-page: 426 ident: bib5 article-title: Antimicrobial efficacy of fruit extracts of two Piper species against selected bacterial and oral fungal pathogens publication-title: Braz. J. Oral Sci. – volume: 9 start-page: 1639 year: 2018 ident: bib47 article-title: Antimicrobial properties and mechanism of action of some plant extracts against food pathogens and spoilage microorganisms publication-title: Front. Microbiol. – ident: bib165 – volume: 97 start-page: 1 year: 2014 end-page: 14 ident: bib3 article-title: Role of herbal bioactives as a potential bioavailability enhancer for active pharmaceutical ingredients publication-title: Fitoterapia – volume: 34 start-page: 115 year: 2014 end-page: 122 ident: bib126 article-title: Evaluation of antioxidant, antibacterial and cytotoxic effects of green synthesized silver nanoparticles by Piper longum fruit publication-title: Mater. Sci. Eng. C. – volume: 153 start-page: 674 year: 2014 end-page: 681 ident: bib51 article-title: Cytochrome P450 inhibitory potential and RP-HPLC standardization of trikatu—a Rasayana from Indian Ayurveda publication-title: J. Ethnopharmacol. – volume: 90 start-page: 339 year: 2004 end-page: 346 ident: bib156 article-title: Immunomodulatory and antitumor activity of Piper longum Linn. and piperine publication-title: J. Ethnopharmacol. – volume: 177 start-page: 191 year: 2015 end-page: 196 ident: bib89 article-title: Identification and simultaneous quantification of five alkaloids in Piper longum L. by HPLC–ESI-MSn and UFLC–ESI-MS/MS and their application to Piper nigrum L publication-title: Food Chem. – volume: 46 start-page: 528 year: 2008 end-page: 533 ident: bib170 article-title: Protective effect of Piper longum L. on oxidative stress induced injury and cellular abnormality in adriamycin induced cardiotoxicity in rats publication-title: Indian J. Exp. Biol. – volume: 13 start-page: 196 year: 2006 end-page: 198 ident: bib28 article-title: Inhibition of CCl4-induced liver fibrosis by Piper longum Linn.? publication-title: Phytomed – start-page: 516 year: 1993 end-page: 520 ident: bib159 article-title: Piperaceae, Flowering Plants· Dicotyledons – volume: 19 start-page: 347 year: 2008 end-page: 361 ident: bib65 article-title: The role of herbs and spices in cancer prevention publication-title: J. Nutr. Biochem. – volume: 3 start-page: 1078 year: 2009 end-page: 1083 ident: bib130 article-title: Antioxidant and antihepatotoxic activities of ethanolic crude extract of Melia azedarach and Piper longum publication-title: J.M.P.R. – volume: 16 start-page: 412 year: 2016 ident: bib52 article-title: Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide publication-title: BMC Complement Altern. Med. – volume: 99 start-page: 538 year: 2002 end-page: 548 ident: bib9 article-title: Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF‐κB and AP‐1 activation and IL‐8 and VEGF expression in human head and neck squamous cell carcinoma lines publication-title: Int. J. Cancer – volume: 17 start-page: 99 year: 1980 end-page: 101 ident: bib30 article-title: Evaluation of fruits of Piper longum Linn. and leaves of Adhatoda vasica Nees for anthelmintic activity publication-title: Indian Drugs – volume: 16 start-page: 1797 year: 1966 end-page: 1800 ident: bib19 article-title: Structure of piperlonguminine, an alkaloid of piper longum linn publication-title: Tetrahedron Lett. – volume: 31 start-page: 921 year: 2010 end-page: 924 ident: bib84 article-title: Alkamides from piper longum and piper nigrum as inhibitors of IL-6 action publication-title: Bull. Korean Chem. Soc. – volume: 52 start-page: 624 year: 2012 end-page: 629 ident: bib33 article-title: Isolation and characterization of antidermatophytic bioactive molecules from Piper longum L. leaves publication-title: Indian J. Microbiol. – start-page: 625 year: 2019 end-page: 655 ident: bib152 article-title: Phytomedicine: A Potential Alternative Medicine in Controlling Neurological Disorders, New Look to Phytomedicine – volume: 13 start-page: 273 year: 2016 ident: bib68 article-title: The future of cancer treatment: immunomodulation, CARs and combination immunotherapy publication-title: Nat. Rev. Clin. Oncol. – volume: 78 start-page: 35 year: 2000 end-page: 39 ident: bib66 article-title: Herbal medicine publication-title: Curr. Sci. – start-page: 105 year: 1944 end-page: 112 ident: bib63 article-title: Structure and development of the ovule and embryo-sac of Piper longum L publication-title: Proceedings of the National Institute of Sciences of India – volume: 51 start-page: 358 year: 2014 end-page: 364 ident: bib139 article-title: Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats publication-title: Indian J. Biochem. Biophys. – volume: 2 start-page: 199 year: 2011 ident: bib121 article-title: Bioefficacy of methanolic root extract of Piper longum L. against isolated strains of Keratinophilic fungi publication-title: J. Basic Clin. Pharm. – volume: 501 start-page: 297 year: 1999 end-page: 300 ident: bib6 article-title: The volatile constituents and microbiological studies on Kaempheria galanga, Hibiscus abelmoschus and Piper longum publication-title: Acta Hortic. (Wagening.) – start-page: 001 year: 2017 end-page: 010 ident: bib18 article-title: Regression of liver fibrosis publication-title: Seminars in Liver Disease – volume: 50 start-page: 167 year: 1996 end-page: 170 ident: bib45 article-title: Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo publication-title: J. Ethnopharmacol. – start-page: 1 year: 2019 end-page: 10 ident: bib87 article-title: Nanoencapsulation of curcumin and its protective effects against CCl4-induced hepatotoxicity in mice publication-title: J. Nanomater. – volume: 47 start-page: 186 year: 2009 end-page: 192 ident: bib161 article-title: Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats publication-title: J. Exp. Biol. – volume: 25 start-page: 46 year: 2017 end-page: 52 ident: bib180 article-title: Herbal medicines as adjuncts to cancer chemotherapy—Part 1: immunomodulators publication-title: Altern. Compl. Ther. – volume: 138 start-page: 3313 year: 2013 end-page: 3320 ident: bib193 article-title: Purification of amide alkaloids from Piper longum L. using preparative two-dimensional normal-phase liquid chromatography × reversed-phase liquid chromatography publication-title: Analyst – volume: 5 start-page: 81 year: 1999 end-page: 88 ident: bib96 article-title: Dementia in ayurveda publication-title: J. Altern. Complement. Med. – volume: 13 start-page: 37 year: 2013 ident: bib104 article-title: Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats publication-title: BMC Complement Altern. Med. – start-page: 407 year: 2019 end-page: 418 ident: bib171 article-title: Adaptogens with a Special Emphasis on Withania Somnifera and Rhodiola Rosea, Nutrition and Enhanced Sports Performance – volume: 7 start-page: 175 year: 2016 ident: bib105 article-title: Immune response of amebiasis and immune evasion by Entamoeba histolytica publication-title: Front. Immunol. – volume: vol. 3 start-page: 146 year: 2006 ident: bib119 publication-title: Handbook of Herbs and Spices – volume: 147 start-page: 373 year: 2013 end-page: 382 ident: bib141 article-title: Anti-snake venom activities of ethanolic extract of fruits of Piper longum L.(Piperaceae) against Russell's viper venom: characterization of piperine as active principle publication-title: J. Ethnopharmacol. – volume: 101 start-page: 129 year: 2017 end-page: 137 ident: bib17 article-title: The renin angiotensin aldosterone system in obesity and hypertension: roles in the cardiorenal metabolic syndrome publication-title: Med. Clínica – volume: 21 start-page: 121 year: 2007 end-page: 124 ident: bib145 article-title: Inhibitory effects of alcoholic extracts of Allium sativum and Piper longum on gross visual motility and glucose uptake of Fasciola gigantica and Gigantocotyle explanatum publication-title: J. Vet. Parasitol. – volume: 14 start-page: 1723 year: 2013 end-page: 1736 ident: bib80 article-title: Screening of antidiabetic and antihyperlipidemic potential of oil from Piper longum and piperine with their possible mechanism publication-title: Expert Opin. Pharmacother. – volume: 3 start-page: 400 year: 2007 end-page: 405 ident: bib166 article-title: Investigation of some piper species for anti—bacterial and anti—inflammatory property publication-title: Int. J. Pharmacol. – volume: 66 start-page: 3063 year: 2018 end-page: 3068 ident: bib179 article-title: Antioxidants: differing meanings in food science and health science publication-title: J. Agric. Food Chem. – volume: 53 start-page: 1516 year: 2015 end-page: 1524 ident: bib16 article-title: Neuroprotective effects of alkaloids from Piper longum in a MPTP-induced mouse model of Parkinson's disease publication-title: Pharm. Biol. – start-page: 895 year: 2019 end-page: 909 ident: bib60 article-title: Biomarkers of Parkinson's Disease, Biomarkers in Toxicology – volume: 71 start-page: 454 year: 2009 ident: bib77 article-title: Antiinflammatory activity of Piper longum fruit oil publication-title: Indian J. Pharm. Sci. – volume: 32 year: 2018 ident: bib109 article-title: Antioxidant, anti‐inflammatory, and enzyme inhibitory activity of natural plant flavonoids and their synthesized derivatives publication-title: J. Biochem. Mol. Toxicol. – volume: 4 start-page: 112 year: 2011 end-page: 116 ident: bib92 article-title: Bioactivity guided isolation of mosquito larvicide from Piper longum publication-title: Asian Pac. J. Trop. Med. – volume: 3 start-page: 852 year: 2007 end-page: 857 ident: bib4 article-title: Antimicrobial screening of different extracts of Piper longum Linn publication-title: Res. J. Agric. Biol. Sci. – volume: 11 start-page: 244 year: 2015 ident: bib127 article-title: Herbs with anti-lipid effects and their interactions with statins as a chemical anti-hyperlipidemia group drugs: a systematic review publication-title: Arya. Atheroscler. – volume: 5 start-page: 93 year: 2018 ident: bib162 article-title: Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: an overview publication-title: Medicines – volume: 123 start-page: 302 year: 2009 end-page: 308 ident: bib147 article-title: Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica publication-title: Exp. Parasitol. – volume: 53 start-page: 334 year: 2018 end-page: 344 ident: bib110 article-title: Advanced glycation end‐products increase IL‐6 and ICAM‐1 expression via RAGE, MAPK and NF‐κB pathways in human gingival fibroblasts publication-title: J. Periodontal. Res. – volume: 96 start-page: 801 year: 2016 end-page: 835 ident: bib138 article-title: Towards green synthesis of nanoparticles: from bio-assisted sources to benign solvents. A review publication-title: Int. J. Environ. Anal. Chem. – volume: 39 start-page: 236 year: 2001 end-page: 238 ident: bib150 article-title: Antibacterial activity of isolates from Piper longum and Taxus baccata publication-title: Pharm. Biol. – volume: 100 start-page: 288 year: 2016 end-page: 294 ident: bib106 article-title: The antioxidant and catalytic activities of green synthesized gold nanoparticles from Piper longum fruit extract publication-title: Process. Saf. Environ. – volume: 18 start-page: 5065 year: 2012 end-page: 5073 ident: bib128 article-title: Leishmania donovani pteridine reductase 1: comparative protein modeling and protein–ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum publication-title: J. Mol. Model. – volume: 17 start-page: 18 year: 2010 end-page: 21 ident: bib154 article-title: Neuroprotective action of Piper longum against MPTP-induced changes in mouse brain publication-title: Ann. Neurosci. – volume: 74 start-page: 189 year: 2001 end-page: 193 ident: bib22 article-title: Embryotoxicity and teratogenicity studies of an ayurvedic contraceptive—pippaliyadi vati publication-title: J. Ethnopharmacol. – volume: 56 start-page: 287 year: 2005 end-page: 291 ident: bib8 article-title: Phenolic contents and antioxidant activity of some food and medicinal plants publication-title: Int. J. Food Sci. Nutr. – year: 2016 ident: bib111 article-title: Medicinal herbals with antiplatelet properties benefit in coronary atherothrombotic diseases publication-title: Thrombosis – volume: 19 start-page: 52 year: 2016 end-page: 58 ident: bib168 article-title: Chemical composition of the essential oils from stem, root, fruit and leaf of Piper longum Linn publication-title: J. Essent Oil. Bear. Pl. – volume: 23 start-page: 1194 year: 2009 end-page: 1196 ident: bib192 article-title: Antihyperlipidemic compounds from the fruit of Piper longum L. publication-title: Phytother Res. – volume: 7 start-page: 1 year: 2015 end-page: 17 ident: bib78 article-title: Phytochemicals having neuroprotective properties from dietary sources and medicinal herbs publication-title: Pharmacog. J. – volume: 12 year: 2017 ident: bib163 article-title: Anthelmintic potential of thymoquinone and curcumin on Fasciola gigantica publication-title: PLoS One – volume: 5 start-page: 2562 year: 2015 end-page: 2567 ident: bib107 article-title: Facile and surfactant-free synthesis of Pd nanoparticles by the extract of the fruits of Piper longum and their catalytic performance for the Sonogashira coupling reaction in water under ligand-and copper-free conditions publication-title: RSC Adv. – volume: 9 year: 2014 ident: bib113 article-title: Evaluation of the efficacy & biochemical mechanism of cell death induction by piper longum extract selectively in in-vitro and in-vivo models of human cancer cells publication-title: PLoS One – volume: 6 start-page: 213 year: 2014 end-page: 222 ident: bib131 article-title: Phytochemical and antimicrobial studies of medicinal plant piper longum linn. I.J.P.P.R. – start-page: 193 year: 2016 end-page: 205 ident: bib50 article-title: Nutraceuticals as Adaptogens: Their Role in Health and Disease, Nutraceuticals. Els – volume: 20 start-page: 235 year: 2006 end-page: 239 ident: bib83 article-title: Antifertility activity of Piper longum Linn. in female rats publication-title: Nat. Prod. Res. – volume: 34 start-page: 73 year: 1997 end-page: 75 ident: bib137 article-title: Characterisation of chemical constituents of Indian long pepper (Piper longum L.) publication-title: J. Food Sci. Technol. – volume: 1 start-page: 129 year: 2010 end-page: 133 ident: bib182 article-title: Antirheumatoid activity of aqueous extract of Piper longum on freunds adjuvant-induced arthritis in rats publication-title: Int. J. Pharm. Sci. Res. – volume: 7 start-page: 65 year: 2008 ident: bib136 article-title: A review of Piper spp.(Piperaceae) phytochemistry, insecticidal activity and mode of action publication-title: Phytochem. Rev. – volume: 22 start-page: 696 year: 2005 end-page: 716 ident: bib129 article-title: An update on bioactive plant lignans publication-title: Nat. Prod. Rep. – volume: 6 start-page: 415 year: 2009 end-page: 420 ident: bib135 article-title: Botanicals and herbs: a traditional approach to treating epilepsy publication-title: Neurotherapeutics – volume: 37 start-page: 10793 year: 2016 end-page: 10804 ident: bib38 article-title: Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo publication-title: Tumor Biol. – volume: 16 start-page: 689 year: 2002 end-page: 691 ident: bib44 article-title: Potential antiamoebic property of the roots of Piper longum Linn publication-title: Phytother. Res. – start-page: 256 year: 2002 end-page: 258 ident: bib32 article-title: Dangerous Tastes: the Story of Spices – start-page: 15 year: 1980 end-page: 19 ident: bib73 article-title: Search for anthelmintics of plant origin: activities of volatile principles of Acorus calamus and Piper longum against Ascaris lumbricoides, 4 publication-title: Asian Symposium on Medicinal Plants and Spices, Bangkok (Thailand) – volume: 642 start-page: 154 year: 2010 end-page: 162 ident: bib10 article-title: Inhibition of lipopolysaccharide-induced inflammatory responses by piperine publication-title: Eur. J. Pharmacol. – volume: 44 start-page: 15944 year: 2005 end-page: 15952 ident: bib79 article-title: Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells publication-title: Biochem – volume: 12 start-page: 603 year: 2000 end-page: 608 ident: bib160 article-title: Fruit oil composition of Piper chaba Hunt., P. longum L. and P. nigrum L publication-title: J. Essent. Oil Res. – volume: 3 start-page: 45 year: 2018 ident: bib116 article-title: First aid and pre-hospital management of venomous snakebites publication-title: Trav. Med. Infect. Dis. – volume: 33 start-page: 17 year: 2019 end-page: 38 ident: bib173 article-title: Venomous bites, stings, and poisoning: an update publication-title: Clin. Infect. Dis. – volume: 38 start-page: 994 year: 2000 end-page: 998 ident: bib2 article-title: Effect of Piper longum Linn, Zingiber officianalis Linn and Ferula species on gastric ulceration and secretion in rats publication-title: Indian J. Exp. Biol. – volume: 13 start-page: 25 year: 2015 end-page: 31 ident: bib72 article-title: Anti-stress and nootropic activity of aqueous extract of Piper longum fruit, estimated by noninvasive biomarkers and Y-maze test in rodents publication-title: Environ. Exp. Biol. – volume: 8 start-page: 8369 year: 2015 ident: bib53 article-title: Anti-angiogenesis or pro-angiogenesis for cancer treatment: focus on drug distribution publication-title: Int. J. Clin. Exp. Med. – start-page: 325 year: 2008 end-page: 347 ident: bib124 article-title: The Indian Herbal Drugs Scenario in Global Perspectives, Bioactive Molecules and Medicinal Plants – volume: 8 start-page: 352 year: 2018 end-page: 360 ident: bib82 article-title: Herbal remedies for liver fibrosis: a review on the mode of action of fifty herbs publication-title: J. Tradit. Complement. Med. – volume: 144 start-page: 781 year: 2005 end-page: 790 ident: bib100 article-title: Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) publication-title: Br. J. Pharmacol. – volume: 7 start-page: 47 year: 2016 ident: bib172 article-title: Promising therapy candidates for liver fibrosis publication-title: Front. Physiol. – volume: 27 start-page: 1511 year: 1988 end-page: 1515 ident: bib35 article-title: Aristolactams and 4, 5-dioxoaporphines from piper longum publication-title: Phytochemistry – volume: 5 start-page: 352 year: 2011 end-page: 376 ident: bib62 article-title: Insight into the hypoglycaemic effect of traditional Indian herbs used in the treatment of diabetes publication-title: Res. J. Med. Plant – volume: 78 start-page: 906 year: 2012 end-page: 908 ident: bib43 article-title: Leishmanicidal compounds from the fruits of Piper longum publication-title: Planta Med. – volume: 182 start-page: 215 year: 2017 end-page: 227 ident: bib97 article-title: Pathogenesis of dermatophytosis: sensing the host tissue publication-title: Mycopathologia – volume: 4 start-page: 223 year: 2006 end-page: 231 ident: bib23 article-title: Ethnobotany of the genus piper (Piperaceae) in Thailand publication-title: Ethnobot. Res. Appl. – volume: 8 start-page: 1 year: 2011 end-page: 13 ident: bib187 article-title: Antioxidant activity of combined ethanolic extract of Eclipta alba and Piper longum Linn publication-title: J. Complement. Integr. Med. – start-page: 35 year: 2013 ident: bib174 article-title: Lead Compounds from Medicinal Plants for the Treatment of Cancer – volume: 1 start-page: 2262 year: 2014 end-page: 2371 ident: bib13 article-title: In vitro antioxidant and antimycobacterial activity of seeds of Piper longum Linn: a comparative study publication-title: SAJ. Pharm. Pharmacol. – volume: 69 start-page: 1 year: 2017 end-page: 14 ident: bib123 article-title: Phytoconstituents as pharmacotherapeutics in rheumatoid arthritis: challenges and scope of nano/submicromedicine in its effective delivery publication-title: J. Pharm. Pharmacol. – volume: 84 start-page: 222 year: 2013 end-page: 226 ident: bib59 article-title: New amide alkaloids from Piper longum publication-title: Fitoterapia – volume: 19 start-page: 77 year: 2017 ident: bib29 article-title: Herbs used for the treatment of hypertension and their mechanism of action publication-title: Curr. Hypertens. Rep. – volume: 3 start-page: 25 year: 2016 ident: bib36 article-title: Essential oils' chemical characterization and investigation of some biological activities: a critical review publication-title: Medicines – volume: 50 start-page: 962 year: 2012 end-page: 967 ident: bib11 article-title: Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats publication-title: Pharm. Biol. – volume: 2 start-page: 416 year: 2014 end-page: 420 ident: bib132 article-title: Piper longum hexane fraction induces infertility by modulation of inflammatory mediators and gonadotripin insufficiency in female rats publication-title: Int. J. Pharm. Pharm. Sci. – volume: 1040 start-page: 193 year: 2004 end-page: 204 ident: bib175 article-title: Preparative isolation and purification of amides from the fruits of Piper longum L. by upright counter-current chromatography and reversed-phase liquid chromatography publication-title: J. Chromatogr., A – volume: 45 start-page: 13 year: 2017 end-page: 22 ident: bib31 article-title: Ginseng on cancer: potential role in modulating inflammation-mediated angiogenesis publication-title: Am. J. Chin. Med. – volume: 212 start-page: 247 year: 2016 end-page: 251 ident: bib149 article-title: Curcumin improves neurofunctions of 6-OHDA-induced parkinsonian rats publication-title: Pathol. Res. Pract. – volume: 39 start-page: 391 year: 2001 end-page: 398 ident: bib102 article-title: Phenolics in Moroccan medicinal plant species as studied by electron spin resonance spectroscopy publication-title: Pharm. Biol. – volume: 46 start-page: 320 year: 2007 end-page: 325 ident: bib15 article-title: Fate of embelin in pippalyadi yoga, an ayurvedic oral contraceptive: structure of embelin-borax complex and evaluation of anti-fertility activity publication-title: Indian J. Chem. B – volume: 15 start-page: 284 year: 2008 end-page: 291 ident: bib143 article-title: Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation publication-title: Phytomedicine – volume: 52 start-page: 308 year: 2015 end-page: 318 ident: bib155 article-title: A pharmacological basis of herbal medicines for epilepsy publication-title: Epilepsy Behav. – volume: 41 start-page: 649 year: 2003 end-page: 651 ident: bib169 article-title: Analgesic activity of Piper longum Linn. root publication-title: J. Exp. Biol. – volume: 55 start-page: 925 year: 2000 end-page: 929 ident: bib55 article-title: Herbal medicines for asthma: a systematic review publication-title: Thorax – volume: 4 start-page: 692 year: 2014 end-page: 696 ident: bib153 article-title: Therapeutic potential of Piper longum L. for disease management-A Review publication-title: Int. J. Pharma. Sci. – volume: 75 start-page: C28 year: 2010 end-page: C35 ident: bib103 article-title: Total phenolic compounds, flavonoids, and radical scavenging activity of 21 selected tropical plants publication-title: J. Food Sci. – year: 2017 ident: bib27 article-title: Piper Longum Linn: A Review of its Phytochemicals and Their Network Pharmacological Evaluation – volume: 5 start-page: 67 year: 2010 end-page: 76 ident: bib184 article-title: Chemistry and pharmacology of Piper longum L publication-title: Int. J. Pharm. Sci. Rev. Res. – volume: 6 start-page: 295 year: 2010 end-page: 303 ident: bib86 article-title: Proteomic evaluation on antiplatelet activity of piperlongumine derived from Piper longum publication-title: Mol. Cell. Toxicol. – start-page: 33 year: 2004 end-page: 39 ident: bib98 article-title: On food and cooking (revised edition) publication-title: Butter and Margarine – volume: 137 start-page: 783 year: 2011 end-page: 789 ident: bib58 article-title: A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease publication-title: J. Ethnopharmacol. – volume: 365 start-page: 2205 year: 2011 end-page: 2219 ident: bib99 article-title: The pathogenesis of rheumatoid arthritis publication-title: N. Engl. J. Med. – volume: 2 start-page: 157 year: 2011 end-page: 161 ident: bib71 article-title: Phytochemical and therapeutic potential of Piper longum Linn a review publication-title: Int. J. Res. Ayurveda Pharm. – volume: 18 start-page: 353 year: 1996 end-page: 355 ident: bib185 article-title: A new dimer of amide from Piper longum publication-title: Acta Bot. Yunnanica – volume: 18 start-page: 17 year: 1980 end-page: 25 ident: bib34 article-title: Medicinal species of Piper, pharmacognostic delimitation publication-title: J. Crude. Drug. Res. – volume: 77–85 year: 2008 ident: bib14 article-title: Volatile constituents of essential oils isolated from leaf and inflorescences of Piper longum Linn publication-title: Chittagong Univ. J. Biol. Sci. – volume: 27 start-page: 124 year: 2017 end-page: 134 ident: bib148 article-title: Natural products assessed in animal models for orofacial pain–a systematic review publication-title: Rev. Bras. Farmacognosia – volume: 10 start-page: 1240 year: 2015 end-page: 1250 ident: bib181 article-title: Traditional Chinese medicine in the prevention and treatment of cancer and cancer metastasis publication-title: Oncol. Lett. – volume: 18 start-page: 1412 year: 2017 ident: bib88 article-title: Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy publication-title: Int. J. Mol. Sci. – volume: 20 start-page: 112 year: 2006 end-page: 116 ident: bib26 article-title: Mast cell stabilizing activity of Piper longum Linn publication-title: Indian J. Allergy Asthma Immunol. – volume: 50 start-page: 3765 year: 2002 end-page: 3767 ident: bib178 article-title: A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae publication-title: J. Agric. Food Chem. – volume: 74 start-page: 1504 year: 2010 end-page: 1506 ident: bib112 article-title: Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells publication-title: Biosci. Biotechnol. Biochem. – start-page: 491 year: 2008 ident: bib70 publication-title: Indian Medicinal Plants: an Illustrated Dictionary – volume: 75 start-page: 1188 year: 1986 end-page: 1189 ident: bib142 article-title: Dehydropipernonaline, an amide possessing coronary vasodilating activity, isolated from Piper iongum L. J publication-title: Pharm. Sci. – volume: 10 start-page: 3400 year: 2009 end-page: 3419 ident: bib48 article-title: Plant antimicrobial agents and their effects on plant and human pathogens publication-title: Int. J. Mol. Sci. – volume: 12 start-page: 478 year: 2013 end-page: 482 ident: bib21 article-title: Evaluation of Angiotensin converting enzyme inhibition and anti-oxidant activity of Piper longum L publication-title: Indian J. Tradit. Knowl. – volume: 8 start-page: 192 year: 2012 end-page: 197 ident: bib67 article-title: In vivo and in vitro antiasthmatic studies of plant Piper longum Linn publication-title: Int. J. Pharmacol. – volume: 33 start-page: 307 year: 2012 ident: bib81 article-title: Anti-inflammatory activity of two varieties of Pippali (Piper longum Linn.) publication-title: Ayu – volume: 37 start-page: 85 year: 1992 end-page: 91 ident: bib61 article-title: An Ayurvedic formulation ‘Trikatu’and its constituents publication-title: J. Ethnopharmacol. – volume: 13 start-page: 143 year: 2011 end-page: 148 ident: bib101 article-title: Two new amides with cytotoxic activity from the fruits of Piper longum publication-title: J. Asian Nat. Prod. Res. – volume: 23 start-page: 10 year: 2014 end-page: 16 ident: bib164 article-title: Diversity study of leaf volatile oil constituent of Piper species based on GC/MS and spatial distribution publication-title: J. Spices Aromat. Crops – volume: 4 start-page: 277 year: 2015 ident: bib176 article-title: Long lasting preventive effects of piperlongumine and a Piper longum extract against stress triggered pathologies in mice publication-title: J. Intercult. Ethnopharmacol. – volume: 58 start-page: 9994 year: 2010 end-page: 10000 ident: bib54 article-title: Phytotoxicity of sarmentine isolated from long pepper (Piper longum) fruit publication-title: J. Agric. Food Chem. – volume: 40 start-page: 64 year: 2008 ident: bib146 article-title: Paralytic effect of alcoholic extract of Allium sativum and Piper longum on liver amphistome, Gigantocotyle explanatum publication-title: Indian J. Pharmacol. – volume: 74 year: 2008 ident: bib64 article-title: Anti-stress, nootropic and anticonvulsant potential of fruit extracts of Piper longum L publication-title: Planta Med. – volume: 10 start-page: 333 year: 2018 end-page: 340 ident: bib74 article-title: Anthelmintic activity of fruit extract and fractions of publication-title: Pharmacog. J. – volume: 9 start-page: 421 issue: 4 year: 2010 ident: 10.1016/j.jep.2019.112255_bib5 article-title: Antimicrobial efficacy of fruit extracts of two Piper species against selected bacterial and oral fungal pathogens publication-title: Braz. J. Oral Sci. – volume: 39 start-page: 1660 issue: 9 year: 2014 ident: 10.1016/j.jep.2019.112255_bib186 article-title: Protective effect of alkaloids from Piper longum in rat dopaminergic neuron injury of 6-OHDA-induced Parkinson's disease publication-title: Zhongguo Zhongyao Zazhi – volume: 7 start-page: 1 issue: 1 year: 2015 ident: 10.1016/j.jep.2019.112255_bib78 article-title: Phytochemicals having neuroprotective properties from dietary sources and medicinal herbs publication-title: Pharmacog. J. doi: 10.5530/pj.2015.1.1 – volume: 4 start-page: 112 issue: 2 year: 2011 ident: 10.1016/j.jep.2019.112255_bib92 article-title: Bioactivity guided isolation of mosquito larvicide from Piper longum publication-title: Asian Pac. J. Trop. Med. doi: 10.1016/S1995-7645(11)60048-5 – volume: 7 start-page: 175 year: 2016 ident: 10.1016/j.jep.2019.112255_bib105 article-title: Immune response of amebiasis and immune evasion by Entamoeba histolytica publication-title: Front. Immunol. doi: 10.3389/fimmu.2016.00175 – volume: 14 start-page: 2090 issue: 9 year: 1975 ident: 10.1016/j.jep.2019.112255_bib37 article-title: Lignans in the seeds of Piper longum publication-title: Phytochemistry doi: 10.1016/0031-9422(75)83139-6 – volume: 146 start-page: 359 issue: 3 year: 2000 ident: 10.1016/j.jep.2019.112255_bib40 article-title: Tansley Review No. 112 Oxygen processing in photosynthesis: regulation and signalling publication-title: New Phytol. doi: 10.1046/j.1469-8137.2000.00667.x – volume: 5 start-page: 93 issue: 3 year: 2018 ident: 10.1016/j.jep.2019.112255_bib162 article-title: Flavonoids and other phenolic compounds from medicinal plants for pharmaceutical and medical aspects: an overview publication-title: Medicines doi: 10.3390/medicines5030093 – volume: 1–4 year: 2019 ident: 10.1016/j.jep.2019.112255_bib1 article-title: N-Alkylamides from Piper longum L. and their stimulative effects on the melanin content and tyrosinase activity in B16 melanoma cells publication-title: Nat. Prod. Res. – volume: 19 start-page: 52 issue: 1 year: 2016 ident: 10.1016/j.jep.2019.112255_bib168 article-title: Chemical composition of the essential oils from stem, root, fruit and leaf of Piper longum Linn publication-title: J. Essent Oil. Bear. Pl. doi: 10.1080/0972060X.2015.1119065 – volume: 66 start-page: 3063 year: 2018 ident: 10.1016/j.jep.2019.112255_bib179 article-title: Antioxidants: differing meanings in food science and health science publication-title: J. Agric. Food Chem. doi: 10.1021/acs.jafc.7b05830 – volume: 71 start-page: 454 issue: 4 year: 2009 ident: 10.1016/j.jep.2019.112255_bib77 article-title: Antiinflammatory activity of Piper longum fruit oil publication-title: Indian J. Pharm. Sci. doi: 10.4103/0250-474X.57300 – volume: 1 start-page: 96 issue: 2 year: 2010 ident: 10.1016/j.jep.2019.112255_bib7 article-title: Bioenhancers: revolutionary concept to market publication-title: J. Ayurveda Integr. Med. doi: 10.4103/0975-9476.65073 – volume: 40 start-page: 64 issue: 2 year: 2008 ident: 10.1016/j.jep.2019.112255_bib146 article-title: Paralytic effect of alcoholic extract of Allium sativum and Piper longum on liver amphistome, Gigantocotyle explanatum publication-title: Indian J. Pharmacol. doi: 10.4103/0253-7613.41040 – volume: 3 start-page: 2196 issue: 7 year: 2018 ident: 10.1016/j.jep.2019.112255_bib114 article-title: Plant adaptogens: natural medicaments for 21st century? publication-title: ChemistrySelect doi: 10.1002/slct.201702682 – volume: 12 start-page: 603 issue: 5 year: 2000 ident: 10.1016/j.jep.2019.112255_bib160 article-title: Fruit oil composition of Piper chaba Hunt., P. longum L. and P. nigrum L publication-title: J. Essent. Oil Res. doi: 10.1080/10412905.2000.9712168 – volume: 101 start-page: 129 issue: 1 year: 2017 ident: 10.1016/j.jep.2019.112255_bib17 article-title: The renin angiotensin aldosterone system in obesity and hypertension: roles in the cardiorenal metabolic syndrome publication-title: Med. Clínica – volume: 9 start-page: 1639 year: 2018 ident: 10.1016/j.jep.2019.112255_bib47 article-title: Antimicrobial properties and mechanism of action of some plant extracts against food pathogens and spoilage microorganisms publication-title: Front. Microbiol. doi: 10.3389/fmicb.2018.01639 – year: 2016 ident: 10.1016/j.jep.2019.112255_bib111 article-title: Medicinal herbals with antiplatelet properties benefit in coronary atherothrombotic diseases publication-title: Thrombosis – volume: 4 start-page: 692 issue: 4 year: 2014 ident: 10.1016/j.jep.2019.112255_bib153 article-title: Therapeutic potential of Piper longum L. for disease management-A Review publication-title: Int. J. Pharma. Sci. – volume: 6 start-page: 161 issue: 1 year: 2007 ident: 10.1016/j.jep.2019.112255_bib95 article-title: Antihyperglycemic and antilipidperoxidative effects of Piper longum (Linn.) dried fruits in alloxan induced diabetic rats publication-title: J. Biol. Sci. doi: 10.3923/jbs.2007.161.168 – volume: 3 start-page: 45 issue: 2 year: 2018 ident: 10.1016/j.jep.2019.112255_bib116 article-title: First aid and pre-hospital management of venomous snakebites publication-title: Trav. Med. Infect. Dis. – volume: 501 start-page: 297 year: 1999 ident: 10.1016/j.jep.2019.112255_bib6 article-title: The volatile constituents and microbiological studies on Kaempheria galanga, Hibiscus abelmoschus and Piper longum publication-title: Acta Hortic. (Wagening.) doi: 10.17660/ActaHortic.1999.501.47 – start-page: 105 year: 1944 ident: 10.1016/j.jep.2019.112255_bib63 article-title: Structure and development of the ovule and embryo-sac of Piper longum L – start-page: 895 year: 2019 ident: 10.1016/j.jep.2019.112255_bib60 – volume: 10 start-page: 1 issue: 1 year: 1958 ident: 10.1016/j.jep.2019.112255_bib183 article-title: The Piperaceae—a family profile publication-title: Brittonia doi: 10.2307/2804687 – volume: 49 start-page: 276 issue: 4 year: 2011 ident: 10.1016/j.jep.2019.112255_bib188 article-title: Hepatoprotective action of ethanolic extracts of Melia azedarach Linn. and Piper longum Linn and their combination on CCl4 induced hepatotoxicity in rats publication-title: Indian J. Exp. Biol. – volume: 8 start-page: 192 issue: 3 year: 2012 ident: 10.1016/j.jep.2019.112255_bib67 article-title: In vivo and in vitro antiasthmatic studies of plant Piper longum Linn publication-title: Int. J. Pharmacol. doi: 10.3923/ijp.2012.192.197 – volume: 144 start-page: 781 issue: 6 year: 2005 ident: 10.1016/j.jep.2019.112255_bib100 article-title: Effects of piperine, the pungent component of black pepper, at the human vanilloid receptor (TRPV1) publication-title: Br. J. Pharmacol. doi: 10.1038/sj.bjp.0706040 – volume: 75 start-page: C28 issue: 1 year: 2010 ident: 10.1016/j.jep.2019.112255_bib103 article-title: Total phenolic compounds, flavonoids, and radical scavenging activity of 21 selected tropical plants publication-title: J. Food Sci. doi: 10.1111/j.1750-3841.2009.01401.x – volume: 177 start-page: 191 year: 2015 ident: 10.1016/j.jep.2019.112255_bib89 article-title: Identification and simultaneous quantification of five alkaloids in Piper longum L. by HPLC–ESI-MSn and UFLC–ESI-MS/MS and their application to Piper nigrum L publication-title: Food Chem. doi: 10.1016/j.foodchem.2015.01.033 – volume: 53 start-page: 334 issue: 3 year: 2018 ident: 10.1016/j.jep.2019.112255_bib110 article-title: Advanced glycation end‐products increase IL‐6 and ICAM‐1 expression via RAGE, MAPK and NF‐κB pathways in human gingival fibroblasts publication-title: J. Periodontal. Res. doi: 10.1111/jre.12518 – volume: 22 start-page: 696 issue: 6 year: 2005 ident: 10.1016/j.jep.2019.112255_bib129 article-title: An update on bioactive plant lignans publication-title: Nat. Prod. Rep. doi: 10.1039/b514045p – volume: 8 start-page: 656 year: 2017 ident: 10.1016/j.jep.2019.112255_bib49 article-title: Therapeutic potential and pharmaceutical development of thymoquinone: a multitargeted molecule of natural origin publication-title: Front. Pharmacol. doi: 10.3389/fphar.2017.00656 – volume: 19 start-page: 347 issue: 6 year: 2008 ident: 10.1016/j.jep.2019.112255_bib65 article-title: The role of herbs and spices in cancer prevention publication-title: J. Nutr. Biochem. doi: 10.1016/j.jnutbio.2007.11.003 – volume: 5 start-page: 352 issue: 4 year: 2011 ident: 10.1016/j.jep.2019.112255_bib62 article-title: Insight into the hypoglycaemic effect of traditional Indian herbs used in the treatment of diabetes publication-title: Res. J. Med. Plant doi: 10.3923/rjmp.2011.352.376 – volume: 66 start-page: 785 issue: 9–10 year: 2007 ident: 10.1016/j.jep.2019.112255_bib90 article-title: GC–MS analysis of the essential oils of piper nigrum L. And piper longum L publication-title: Chromatographia doi: 10.1365/s10337-007-0408-2 – volume: 5 start-page: 67 issue: 1 year: 2010 ident: 10.1016/j.jep.2019.112255_bib184 article-title: Chemistry and pharmacology of Piper longum L publication-title: Int. J. Pharm. Sci. Rev. Res. – volume: 7 start-page: 47 year: 2016 ident: 10.1016/j.jep.2019.112255_bib172 article-title: Promising therapy candidates for liver fibrosis publication-title: Front. Physiol. doi: 10.3389/fphys.2016.00047 – volume: 13 start-page: 196 issue: 3 year: 2006 ident: 10.1016/j.jep.2019.112255_bib28 article-title: Inhibition of CCl4-induced liver fibrosis by Piper longum Linn.? publication-title: Phytomed doi: 10.1016/j.phymed.2004.01.009 – volume: 25 start-page: 46 issue: 1 year: 2017 ident: 10.1016/j.jep.2019.112255_bib180 article-title: Herbal medicines as adjuncts to cancer chemotherapy—Part 1: immunomodulators publication-title: Altern. Compl. Ther. doi: 10.1089/act.2018.29201.eya – volume: 108 start-page: 445 issue: 3 year: 2006 ident: 10.1016/j.jep.2019.112255_bib122 article-title: HPLC assisted chemobiological standardization of α-glucosidase-I enzyme inhibitory constituents from Piper longum Linn-An Indian medicinal plant publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2006.06.004 – volume: 123 start-page: 302 issue: 4 year: 2009 ident: 10.1016/j.jep.2019.112255_bib147 article-title: Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica publication-title: Exp. Parasitol. doi: 10.1016/j.exppara.2009.08.002 – volume: 3 start-page: 277 issue: 6 year: 2013 ident: 10.1016/j.jep.2019.112255_bib177 article-title: New amide alkaloids from Piper longum fruits publication-title: Nat. Prod. Bioprospect doi: 10.1007/s13659-013-0073-0 – volume: 50 start-page: 3765 issue: 13 year: 2002 ident: 10.1016/j.jep.2019.112255_bib178 article-title: A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae publication-title: J. Agric. Food Chem. doi: 10.1021/jf011708f – volume: 17 start-page: 99 issue: 4 year: 1980 ident: 10.1016/j.jep.2019.112255_bib30 article-title: Evaluation of fruits of Piper longum Linn. and leaves of Adhatoda vasica Nees for anthelmintic activity publication-title: Indian Drugs – volume: 97 start-page: 1 year: 2014 ident: 10.1016/j.jep.2019.112255_bib3 article-title: Role of herbal bioactives as a potential bioavailability enhancer for active pharmaceutical ingredients publication-title: Fitoterapia doi: 10.1016/j.fitote.2014.05.005 – volume: 17 start-page: 18 issue: 1 year: 2010 ident: 10.1016/j.jep.2019.112255_bib154 article-title: Neuroprotective action of Piper longum against MPTP-induced changes in mouse brain publication-title: Ann. Neurosci. doi: 10.5214/ans.0972.7531.2010.170105 – volume: 99 start-page: 538 issue: 4 year: 2002 ident: 10.1016/j.jep.2019.112255_bib9 article-title: Effects of pharmacologic antagonists of epidermal growth factor receptor, PI3K and MEK signal kinases on NF‐κB and AP‐1 activation and IL‐8 and VEGF expression in human head and neck squamous cell carcinoma lines publication-title: Int. J. Cancer doi: 10.1002/ijc.10398 – start-page: 33 year: 2004 ident: 10.1016/j.jep.2019.112255_bib98 article-title: On food and cooking (revised edition) – volume: 47 start-page: 643 year: 2009 ident: 10.1016/j.jep.2019.112255_bib118 article-title: Molluscicidal activity of piper cubeba linn., piper longum linn. And tribulus terrestris linn. and their combinations against snail indoplanorbis exustus desh publication-title: Indian J. Exp. Biol. – volume: 5 start-page: 2562 issue: 4 year: 2015 ident: 10.1016/j.jep.2019.112255_bib107 article-title: Facile and surfactant-free synthesis of Pd nanoparticles by the extract of the fruits of Piper longum and their catalytic performance for the Sonogashira coupling reaction in water under ligand-and copper-free conditions publication-title: RSC Adv. doi: 10.1039/C4RA12875C – start-page: 35 year: 2013 ident: 10.1016/j.jep.2019.112255_bib174 – volume: 16 start-page: 689 issue: 7 year: 2002 ident: 10.1016/j.jep.2019.112255_bib44 article-title: Potential antiamoebic property of the roots of Piper longum Linn publication-title: Phytother. Res. doi: 10.1002/ptr.1014 – volume: 75 start-page: 1188 issue: 12 year: 1986 ident: 10.1016/j.jep.2019.112255_bib142 article-title: Dehydropipernonaline, an amide possessing coronary vasodilating activity, isolated from Piper iongum L. J publication-title: Pharm. Sci. doi: 10.1002/jps.2600751215 – volume: 6 start-page: 111 issue: 2 year: 2007 ident: 10.1016/j.jep.2019.112255_bib69 article-title: Antimicrobial activity of Piper fruits publication-title: IJNPR – volume: 147 start-page: 373 issue: 2 year: 2013 ident: 10.1016/j.jep.2019.112255_bib141 article-title: Anti-snake venom activities of ethanolic extract of fruits of Piper longum L.(Piperaceae) against Russell's viper venom: characterization of piperine as active principle publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2013.03.022 – volume: 3 start-page: 852 issue: 6 year: 2007 ident: 10.1016/j.jep.2019.112255_bib4 article-title: Antimicrobial screening of different extracts of Piper longum Linn publication-title: Res. J. Agric. Biol. Sci. – volume: 100 start-page: 288 year: 2016 ident: 10.1016/j.jep.2019.112255_bib106 article-title: The antioxidant and catalytic activities of green synthesized gold nanoparticles from Piper longum fruit extract publication-title: Process. Saf. Environ. doi: 10.1016/j.psep.2016.02.007 – volume: 137 start-page: 783 issue: 1 year: 2011 ident: 10.1016/j.jep.2019.112255_bib58 article-title: A modified formulation of Chinese traditional medicine improves memory impairment and reduces Aβ level in the Tg-APPswe/PS1dE9 mouse model of Alzheimer's disease publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2011.06.046 – volume: 2 start-page: 199 issue: 4 year: 2011 ident: 10.1016/j.jep.2019.112255_bib121 article-title: Bioefficacy of methanolic root extract of Piper longum L. against isolated strains of Keratinophilic fungi publication-title: J. Basic Clin. Pharm. – volume: 39 start-page: 391 issue: 5 year: 2001 ident: 10.1016/j.jep.2019.112255_bib102 article-title: Phenolics in Moroccan medicinal plant species as studied by electron spin resonance spectroscopy publication-title: Pharm. Biol. doi: 10.1076/phbi.39.5.391.5893 – volume: 38 start-page: 994 year: 2000 ident: 10.1016/j.jep.2019.112255_bib2 article-title: Effect of Piper longum Linn, Zingiber officianalis Linn and Ferula species on gastric ulceration and secretion in rats publication-title: Indian J. Exp. Biol. – volume: 4 start-page: 277 issue: 4 year: 2015 ident: 10.1016/j.jep.2019.112255_bib176 article-title: Long lasting preventive effects of piperlongumine and a Piper longum extract against stress triggered pathologies in mice publication-title: J. Intercult. Ethnopharmacol. doi: 10.5455/jice.20150921010411 – volume: 23 start-page: 1194 issue: 8 year: 2009 ident: 10.1016/j.jep.2019.112255_bib192 article-title: Antihyperlipidemic compounds from the fruit of Piper longum L. publication-title: Phytother Res. doi: 10.1002/ptr.2630 – volume: 55 start-page: 925 issue: 11 year: 2000 ident: 10.1016/j.jep.2019.112255_bib55 article-title: Herbal medicines for asthma: a systematic review publication-title: Thorax doi: 10.1136/thorax.55.11.925 – start-page: 1 year: 2019 ident: 10.1016/j.jep.2019.112255_bib87 article-title: Nanoencapsulation of curcumin and its protective effects against CCl4-induced hepatotoxicity in mice publication-title: J. Nanomater. – volume: 11 start-page: 244 issue: 4 year: 2015 ident: 10.1016/j.jep.2019.112255_bib127 article-title: Herbs with anti-lipid effects and their interactions with statins as a chemical anti-hyperlipidemia group drugs: a systematic review publication-title: Arya. Atheroscler. – volume: 116 start-page: 48 year: 2019 ident: 10.1016/j.jep.2019.112255_bib24 article-title: Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells publication-title: Cytokine doi: 10.1016/j.cyto.2019.01.001 – volume: 74 start-page: 189 issue: 2 year: 2001 ident: 10.1016/j.jep.2019.112255_bib22 article-title: Embryotoxicity and teratogenicity studies of an ayurvedic contraceptive—pippaliyadi vati publication-title: J. Ethnopharmacol. doi: 10.1016/S0378-8741(00)00354-8 – volume: 1 start-page: 2262 issue: 101 year: 2014 ident: 10.1016/j.jep.2019.112255_bib13 article-title: In vitro antioxidant and antimycobacterial activity of seeds of Piper longum Linn: a comparative study publication-title: SAJ. Pharm. Pharmacol. – volume: 2 start-page: 157 issue: 1 year: 2011 ident: 10.1016/j.jep.2019.112255_bib71 article-title: Phytochemical and therapeutic potential of Piper longum Linn a review publication-title: Int. J. Res. Ayurveda Pharm. – volume: 52 start-page: 3561 issue: 6 year: 2015 ident: 10.1016/j.jep.2019.112255_bib76 article-title: Effect on oxidative stress, glucose uptake level and lipid droplet content by Apigenin 7, 4'-dimethyl ether isolated from Piper longum L publication-title: J. Food Sci. Technol. – volume: 9 issue: 11 year: 2014 ident: 10.1016/j.jep.2019.112255_bib113 article-title: Evaluation of the efficacy & biochemical mechanism of cell death induction by piper longum extract selectively in in-vitro and in-vivo models of human cancer cells publication-title: PLoS One doi: 10.1371/journal.pone.0113250 – volume: 69 start-page: 487 issue: 4 year: 2016 ident: 10.1016/j.jep.2019.112255_bib42 article-title: Acaricide resistance in Rhipicephalus (Boophilus) microplus and Hyalomma anatolicum collected from Haryana and Rajasthan states of India publication-title: Exp. Appl. Acarol. doi: 10.1007/s10493-016-0046-1 – volume: 6 start-page: 295 issue: 3 year: 2010 ident: 10.1016/j.jep.2019.112255_bib86 article-title: Proteomic evaluation on antiplatelet activity of piperlongumine derived from Piper longum publication-title: Mol. Cell. Toxicol. doi: 10.1007/s13273-010-0040-3 – volume: 74 start-page: 1504 issue: 7 year: 2010 ident: 10.1016/j.jep.2019.112255_bib112 article-title: Inhibitory effects of bakuchiol, bavachin, and isobavachalcone isolated from Piper longum on melanin production in B16 mouse melanoma cells publication-title: Biosci. Biotechnol. Biochem. doi: 10.1271/bbb.100221 – volume: 77–85 year: 2008 ident: 10.1016/j.jep.2019.112255_bib14 article-title: Volatile constituents of essential oils isolated from leaf and inflorescences of Piper longum Linn publication-title: Chittagong Univ. J. Biol. Sci. – volume: 41 start-page: 649 issue: 6 year: 2003 ident: 10.1016/j.jep.2019.112255_bib169 article-title: Analgesic activity of Piper longum Linn. root publication-title: J. Exp. Biol. – volume: 71 start-page: 303 issue: 3 year: 2017 ident: 10.1016/j.jep.2019.112255_bib144 article-title: In vitro assessment of the acaricidal activity of Piper longum, Piper nigrum, and Zingiber officinale extracts against Hyalomma anatolicum ticks publication-title: Exp. Appl. Acarol. doi: 10.1007/s10493-017-0113-2 – volume: 78 start-page: 35 issue: 1 year: 2000 ident: 10.1016/j.jep.2019.112255_bib66 article-title: Herbal medicine publication-title: Curr. Sci. – start-page: 491 year: 2008 ident: 10.1016/j.jep.2019.112255_bib70 – volume: 212 start-page: 247 issue: 4 year: 2016 ident: 10.1016/j.jep.2019.112255_bib149 article-title: Curcumin improves neurofunctions of 6-OHDA-induced parkinsonian rats publication-title: Pathol. Res. Pract. doi: 10.1016/j.prp.2015.11.012 – volume: 3 start-page: 400 issue: 5 year: 2007 ident: 10.1016/j.jep.2019.112255_bib166 article-title: Investigation of some piper species for anti—bacterial and anti—inflammatory property publication-title: Int. J. Pharmacol. doi: 10.3923/ijp.2007.400.405 – year: 2009 ident: 10.1016/j.jep.2019.112255_bib39 – volume: 20 start-page: 112 issue: 2 year: 2006 ident: 10.1016/j.jep.2019.112255_bib26 article-title: Mast cell stabilizing activity of Piper longum Linn publication-title: Indian J. Allergy Asthma Immunol. – volume: 21 start-page: 121 issue: 2 year: 2007 ident: 10.1016/j.jep.2019.112255_bib145 article-title: Inhibitory effects of alcoholic extracts of Allium sativum and Piper longum on gross visual motility and glucose uptake of Fasciola gigantica and Gigantocotyle explanatum publication-title: J. Vet. Parasitol. – volume: 10 start-page: 1240 issue: 3 year: 2015 ident: 10.1016/j.jep.2019.112255_bib181 article-title: Traditional Chinese medicine in the prevention and treatment of cancer and cancer metastasis publication-title: Oncol. Lett. doi: 10.3892/ol.2015.3459 – volume: 18 start-page: 353 issue: 3 year: 1996 ident: 10.1016/j.jep.2019.112255_bib185 article-title: A new dimer of amide from Piper longum publication-title: Acta Bot. Yunnanica – volume: 14 start-page: 853 issue: 12 year: 2007 ident: 10.1016/j.jep.2019.112255_bib115 article-title: Antiplatelet effects of acidamides isolated from the fruits of Piper longum L publication-title: Phytomedicine doi: 10.1016/j.phymed.2007.06.011 – volume: 12 start-page: 478 year: 2013 ident: 10.1016/j.jep.2019.112255_bib21 article-title: Evaluation of Angiotensin converting enzyme inhibition and anti-oxidant activity of Piper longum L publication-title: Indian J. Tradit. Knowl. – volume: 47 start-page: 186 year: 2009 ident: 10.1016/j.jep.2019.112255_bib161 article-title: Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats publication-title: J. Exp. Biol. – volume: 11 start-page: 1 issue: 03 year: 2017 ident: 10.1016/j.jep.2019.112255_bib167 article-title: Scientific justification of anthelmintic medicines based on medicinal plant material. I.J.G.P. – volume: 84 start-page: 222 year: 2013 ident: 10.1016/j.jep.2019.112255_bib59 article-title: New amide alkaloids from Piper longum publication-title: Fitoterapia doi: 10.1016/j.fitote.2012.12.001 – volume: 52 start-page: 624 issue: 4 year: 2012 ident: 10.1016/j.jep.2019.112255_bib33 article-title: Isolation and characterization of antidermatophytic bioactive molecules from Piper longum L. leaves publication-title: Indian J. Microbiol. doi: 10.1007/s12088-012-0303-x – volume: 3 start-page: 119 issue: 3 year: 2009 ident: 10.1016/j.jep.2019.112255_bib57 article-title: Anti-oxidant activity of piper longum linn publication-title: Int. J. Biol. Chem. doi: 10.3923/ijbc.2009.119.125 – volume: 13 start-page: 25 year: 2015 ident: 10.1016/j.jep.2019.112255_bib72 article-title: Anti-stress and nootropic activity of aqueous extract of Piper longum fruit, estimated by noninvasive biomarkers and Y-maze test in rodents publication-title: Environ. Exp. Biol. – volume: 8 start-page: 8369 issue: 6 year: 2015 ident: 10.1016/j.jep.2019.112255_bib53 article-title: Anti-angiogenesis or pro-angiogenesis for cancer treatment: focus on drug distribution publication-title: Int. J. Clin. Exp. Med. – volume: 50 start-page: 962 issue: 8 year: 2012 ident: 10.1016/j.jep.2019.112255_bib11 article-title: Hypolipidemic effects of a new piperine derivative GB-N from Piper longum in high-fat diet-fed rats publication-title: Pharm. Biol. doi: 10.3109/13880209.2012.654395 – volume: 4 start-page: 223 year: 2006 ident: 10.1016/j.jep.2019.112255_bib23 article-title: Ethnobotany of the genus piper (Piperaceae) in Thailand publication-title: Ethnobot. Res. Appl. doi: 10.17348/era.4.0.223-231 – volume: 54 start-page: 9759 issue: 26 year: 2006 ident: 10.1016/j.jep.2019.112255_bib85 article-title: Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum publication-title: J. Agric. Food Chem. doi: 10.1021/jf061402e – volume: 8 start-page: 352 issue: 3 year: 2018 ident: 10.1016/j.jep.2019.112255_bib82 article-title: Herbal remedies for liver fibrosis: a review on the mode of action of fifty herbs publication-title: J. Tradit. Complement. Med. doi: 10.1016/j.jtcme.2017.07.002 – volume: 37 start-page: 85 issue: 2 year: 1992 ident: 10.1016/j.jep.2019.112255_bib61 article-title: An Ayurvedic formulation ‘Trikatu’and its constituents publication-title: J. Ethnopharmacol. doi: 10.1016/0378-8741(92)90067-2 – volume: 7 start-page: 65 issue: 1 year: 2008 ident: 10.1016/j.jep.2019.112255_bib136 article-title: A review of Piper spp.(Piperaceae) phytochemistry, insecticidal activity and mode of action publication-title: Phytochem. Rev. doi: 10.1007/s11101-006-9058-5 – volume: 51 start-page: 358 year: 2014 ident: 10.1016/j.jep.2019.112255_bib139 article-title: Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats publication-title: Indian J. Biochem. Biophys. – volume: 50 start-page: 167 issue: 3 year: 1996 ident: 10.1016/j.jep.2019.112255_bib45 article-title: Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo publication-title: J. Ethnopharmacol. doi: 10.1016/0378-8741(96)01382-7 – volume: 138 start-page: 3313 issue: 11 year: 2013 ident: 10.1016/j.jep.2019.112255_bib193 article-title: Purification of amide alkaloids from Piper longum L. using preparative two-dimensional normal-phase liquid chromatography × reversed-phase liquid chromatography publication-title: Analyst doi: 10.1039/c3an00016h – volume: 4 start-page: 854 issue: 5 year: 2019 ident: 10.1016/j.jep.2019.112255_bib75 article-title: Past and future spread of the arbovirus vectors Aedes aegypti and Aedes albopictus publication-title: Nat. Microbiol. doi: 10.1038/s41564-019-0376-y – volume: 9 issue: 5 year: 2014 ident: 10.1016/j.jep.2019.112255_bib41 article-title: Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation publication-title: PLoS One doi: 10.1371/journal.pone.0094298 – volume: 16 start-page: 1797 year: 1966 ident: 10.1016/j.jep.2019.112255_bib19 article-title: Structure of piperlonguminine, an alkaloid of piper longum linn publication-title: Tetrahedron Lett. doi: 10.1016/S0040-4039(01)99798-9 – volume: 18 start-page: 1412 issue: 7 year: 2017 ident: 10.1016/j.jep.2019.112255_bib88 article-title: Natural compounds from herbs that can potentially execute as autophagy inducers for cancer therapy publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms18071412 – volume: 69 start-page: 1 issue: 1 year: 2017 ident: 10.1016/j.jep.2019.112255_bib123 article-title: Phytoconstituents as pharmacotherapeutics in rheumatoid arthritis: challenges and scope of nano/submicromedicine in its effective delivery publication-title: J. Pharm. Pharmacol. doi: 10.1111/jphp.12661 – start-page: 407 year: 2019 ident: 10.1016/j.jep.2019.112255_bib171 – volume: 37 start-page: 10793 issue: 8 year: 2016 ident: 10.1016/j.jep.2019.112255_bib38 article-title: Piperlongumine induces gastric cancer cell apoptosis and G2/M cell cycle arrest both in vitro and in vivo publication-title: Tumor Biol. doi: 10.1007/s13277-016-4792-9 – volume: 36 start-page: 997 issue: 3 year: 2013 ident: 10.1016/j.jep.2019.112255_bib108 article-title: Green nanotechnology–a new hope for medical biology publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2013.09.002 – start-page: 516 year: 1993 ident: 10.1016/j.jep.2019.112255_bib159 – year: 2017 ident: 10.1016/j.jep.2019.112255_bib27 – volume: 18 start-page: 5065 issue: 12 year: 2012 ident: 10.1016/j.jep.2019.112255_bib128 article-title: Leishmania donovani pteridine reductase 1: comparative protein modeling and protein–ligand interaction studies of the leishmanicidal constituents isolated from the fruits of Piper longum publication-title: J. Mol. Model. doi: 10.1007/s00894-012-1508-y – volume: 87 start-page: 92 year: 2015 ident: 10.1016/j.jep.2019.112255_bib140 article-title: Characterization of the lipopolysaccharide induced model of Parkinson's disease: role of oxidative stress and neuroinflammation publication-title: Neurochem. Int. doi: 10.1016/j.neuint.2015.06.004 – volume: 15 start-page: 284 issue: 4 year: 2008 ident: 10.1016/j.jep.2019.112255_bib143 article-title: Piper longum Linn. Extract inhibits TNF-α-induced expression of cell adhesion molecules by inhibiting NF-κB activation and microsomal lipid peroxidation publication-title: Phytomedicine doi: 10.1016/j.phymed.2007.06.007 – volume: 23 start-page: 1769 issue: 4 year: 1967 ident: 10.1016/j.jep.2019.112255_bib20 article-title: Alkaloids of Piper longum Linn—I: structure and synthesis of piperlongumine and piperlonguminine publication-title: Tetrahedron doi: 10.1016/S0040-4020(01)82575-8 – volume: 11 start-page: 156 issue: 3 year: 2015 ident: 10.1016/j.jep.2019.112255_bib25 article-title: Piperine: a comprehensive review of pre-clinical and clinical investigations publication-title: Curr. Bioact. Compd. doi: 10.2174/1573407211666150915214425 – volume: 30 start-page: 1221 issue: 7 year: 2007 ident: 10.1016/j.jep.2019.112255_bib56 article-title: Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A2 receptor publication-title: Biol. Pharm. Bull. doi: 10.1248/bpb.30.1221 – volume: 19 start-page: 77 issue: 9 year: 2017 ident: 10.1016/j.jep.2019.112255_bib29 article-title: Herbs used for the treatment of hypertension and their mechanism of action publication-title: Curr. Hypertens. Rep. doi: 10.1007/s11906-017-0775-5 – volume: 78 start-page: 906 issue: 09 year: 2012 ident: 10.1016/j.jep.2019.112255_bib43 article-title: Leishmanicidal compounds from the fruits of Piper longum publication-title: Planta Med. doi: 10.1055/s-0031-1298537 – volume: 53 start-page: 1516 issue: 10 year: 2015 ident: 10.1016/j.jep.2019.112255_bib16 article-title: Neuroprotective effects of alkaloids from Piper longum in a MPTP-induced mouse model of Parkinson's disease publication-title: Pharm. Biol. doi: 10.3109/13880209.2014.991835 – volume: 20 start-page: 235 issue: 3 year: 2006 ident: 10.1016/j.jep.2019.112255_bib83 article-title: Antifertility activity of Piper longum Linn. in female rats publication-title: Nat. Prod. Res. doi: 10.1080/14786410500045465 – start-page: 256 year: 2002 ident: 10.1016/j.jep.2019.112255_bib32 – volume: 6 start-page: 415 issue: 2 year: 2009 ident: 10.1016/j.jep.2019.112255_bib135 article-title: Botanicals and herbs: a traditional approach to treating epilepsy publication-title: Neurotherapeutics doi: 10.1016/j.nurt.2008.12.004 – volume: 10 start-page: 3400 issue: 8 year: 2009 ident: 10.1016/j.jep.2019.112255_bib48 article-title: Plant antimicrobial agents and their effects on plant and human pathogens publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms10083400 – start-page: 193 year: 2016 ident: 10.1016/j.jep.2019.112255_bib50 – volume: 1 start-page: 147 issue: 6 year: 2013 ident: 10.1016/j.jep.2019.112255_bib120 article-title: Golden heart of the nature: piper betle L publication-title: J. Pharmacogn. Phytochem. – volume: 39 start-page: 236 issue: 3 year: 2001 ident: 10.1016/j.jep.2019.112255_bib150 article-title: Antibacterial activity of isolates from Piper longum and Taxus baccata publication-title: Pharm. Biol. doi: 10.1076/phbi.39.3.236.5926 – start-page: 325 year: 2008 ident: 10.1016/j.jep.2019.112255_bib124 – volume: 91 start-page: 357 issue: 2–3 year: 2004 ident: 10.1016/j.jep.2019.112255_bib134 article-title: Effects of Piper longum fruit, Piper sarmentosum root and Quercus infectoria nut gall on caecal amoebiasis in mice publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2004.01.014 – volume: 6 start-page: 733 issue: 5 year: 2006 ident: 10.1016/j.jep.2019.112255_bib157 article-title: Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2005.10.013 – volume: 1040 start-page: 193 issue: 2 year: 2004 ident: 10.1016/j.jep.2019.112255_bib175 article-title: Preparative isolation and purification of amides from the fruits of Piper longum L. by upright counter-current chromatography and reversed-phase liquid chromatography publication-title: J. Chromatogr., A doi: 10.1016/j.chroma.2004.03.056 – start-page: 001 year: 2017 ident: 10.1016/j.jep.2019.112255_bib18 article-title: Regression of liver fibrosis – volume: 15 start-page: 1280 issue: 2 year: 2015 ident: 10.1016/j.jep.2019.112255_bib94 article-title: Biogenic preparation of gold nanostructures reduced from Piper longum leaf broth and their electrochemical studies publication-title: J. Nanosci. Nanotechnol. doi: 10.1166/jnn.2015.8889 – volume: 32 issue: 1 year: 2018 ident: 10.1016/j.jep.2019.112255_bib109 article-title: Antioxidant, anti‐inflammatory, and enzyme inhibitory activity of natural plant flavonoids and their synthesized derivatives publication-title: J. Biochem. Mol. Toxicol. doi: 10.1002/jbt.22002 – volume: 23 start-page: 10 issue: 1 year: 2014 ident: 10.1016/j.jep.2019.112255_bib164 article-title: Diversity study of leaf volatile oil constituent of Piper species based on GC/MS and spatial distribution publication-title: J. Spices Aromat. Crops – volume: 642 start-page: 154 issue: 1–3 year: 2010 ident: 10.1016/j.jep.2019.112255_bib10 article-title: Inhibition of lipopolysaccharide-induced inflammatory responses by piperine publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2010.05.026 – volume: 16 start-page: 412 issue: 1 year: 2016 ident: 10.1016/j.jep.2019.112255_bib52 article-title: Alkaloids from piper longum protect dopaminergic neurons against inflammation-mediated damage induced by intranigral injection of lipopolysaccharide publication-title: BMC Complement Altern. Med. doi: 10.1186/s12906-016-1392-6 – volume: 31 start-page: 921 issue: 4 year: 2010 ident: 10.1016/j.jep.2019.112255_bib84 article-title: Alkamides from piper longum and piper nigrum as inhibitors of IL-6 action publication-title: Bull. Korean Chem. Soc. doi: 10.5012/bkcs.2010.31.04.921 – volume: 365 start-page: 2205 issue: 23 year: 2011 ident: 10.1016/j.jep.2019.112255_bib99 article-title: The pathogenesis of rheumatoid arthritis publication-title: N. Engl. J. Med. doi: 10.1056/NEJMra1004965 – volume: 92 start-page: 856 year: 2017 ident: 10.1016/j.jep.2019.112255_bib151 article-title: Important medicinal herbs in Parkinson's disease pharmacotherapy publication-title: Biomed. Pharmacother. doi: 10.1016/j.biopha.2017.05.137 – volume: 58 start-page: 9994 issue: 18 year: 2010 ident: 10.1016/j.jep.2019.112255_bib54 article-title: Phytotoxicity of sarmentine isolated from long pepper (Piper longum) fruit publication-title: J. Agric. Food Chem. doi: 10.1021/jf102087c – volume: 182 start-page: 215 issue: 1–2 year: 2017 ident: 10.1016/j.jep.2019.112255_bib97 article-title: Pathogenesis of dermatophytosis: sensing the host tissue publication-title: Mycopathologia doi: 10.1007/s11046-016-0057-9 – volume: 33 start-page: 17 issue: 1 year: 2019 ident: 10.1016/j.jep.2019.112255_bib173 article-title: Venomous bites, stings, and poisoning: an update publication-title: Clin. Infect. Dis. doi: 10.1016/j.idc.2018.10.001 – volume: 52 start-page: 308 year: 2015 ident: 10.1016/j.jep.2019.112255_bib155 article-title: A pharmacological basis of herbal medicines for epilepsy publication-title: Epilepsy Behav. doi: 10.1016/j.yebeh.2015.05.012 – volume: 3 start-page: 25 issue: 4 year: 2016 ident: 10.1016/j.jep.2019.112255_bib36 article-title: Essential oils' chemical characterization and investigation of some biological activities: a critical review publication-title: Medicines doi: 10.3390/medicines3040025 – volume: 29 start-page: 1166 issue: 12 year: 2015 ident: 10.1016/j.jep.2019.112255_bib133 article-title: Spermicidal activity of the hexane extract of Piper longum: an in vitro study publication-title: Nat. Prod. Rep. doi: 10.1080/14786419.2014.981812 – volume: 29 start-page: 537 issue: 5 year: 2001 ident: 10.1016/j.jep.2019.112255_bib93 article-title: Tetrahydropiperine, the first natural aryl pentanamide from Piper longum publication-title: Biochem. Syst. Ecol. doi: 10.1016/S0305-1978(00)00083-1 – volume: 45 start-page: 13 issue: 01 year: 2017 ident: 10.1016/j.jep.2019.112255_bib31 article-title: Ginseng on cancer: potential role in modulating inflammation-mediated angiogenesis publication-title: Am. J. Chin. Med. doi: 10.1142/S0192415X17500021 – volume: 13 start-page: 37 issue: 1 year: 2013 ident: 10.1016/j.jep.2019.112255_bib104 article-title: Antidiabetic and antihyperlipidemic activity of Piper longum root aqueous extract in STZ induced diabetic rats publication-title: BMC Complement Altern. Med. doi: 10.1186/1472-6882-13-37 – volume: 90 start-page: 339 issue: 2–3 year: 2004 ident: 10.1016/j.jep.2019.112255_bib156 article-title: Immunomodulatory and antitumor activity of Piper longum Linn. and piperine publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2003.10.016 – volume: 120 start-page: 8891 issue: 6 year: 2019 ident: 10.1016/j.jep.2019.112255_bib158 article-title: Molecular mechanisms, prevalence, and molecular methods for familial combined hyperlipidemia disease: a review publication-title: J. Cell. Biochem. doi: 10.1002/jcb.28311 – volume: 1 start-page: 129 issue: 9 year: 2010 ident: 10.1016/j.jep.2019.112255_bib182 article-title: Antirheumatoid activity of aqueous extract of Piper longum on freunds adjuvant-induced arthritis in rats publication-title: Int. J. Pharm. Sci. Res. – start-page: 625 year: 2019 ident: 10.1016/j.jep.2019.112255_bib152 – volume: 46 start-page: 528 year: 2008 ident: 10.1016/j.jep.2019.112255_bib170 article-title: Protective effect of Piper longum L. on oxidative stress induced injury and cellular abnormality in adriamycin induced cardiotoxicity in rats publication-title: Indian J. Exp. Biol. – volume: 27 start-page: 1511 issue: 5 year: 1988 ident: 10.1016/j.jep.2019.112255_bib35 article-title: Aristolactams and 4, 5-dioxoaporphines from piper longum publication-title: Phytochemistry doi: 10.1016/0031-9422(88)80226-7 – volume: 13 start-page: 273 issue: 5 year: 2016 ident: 10.1016/j.jep.2019.112255_bib68 article-title: The future of cancer treatment: immunomodulation, CARs and combination immunotherapy publication-title: Nat. Rev. Clin. Oncol. doi: 10.1038/nrclinonc.2016.25 – volume: 5 start-page: 81 issue: 1 year: 1999 ident: 10.1016/j.jep.2019.112255_bib96 article-title: Dementia in ayurveda publication-title: J. Altern. Complement. Med. doi: 10.1089/acm.1999.5.81 – volume: 2 start-page: 416 year: 2014 ident: 10.1016/j.jep.2019.112255_bib132 article-title: Piper longum hexane fraction induces infertility by modulation of inflammatory mediators and gonadotripin insufficiency in female rats publication-title: Int. J. Pharm. Pharm. Sci. – volume: vol. 3 start-page: 146 year: 2006 ident: 10.1016/j.jep.2019.112255_bib119 – volume: 14 start-page: 1723 issue: 13 year: 2013 ident: 10.1016/j.jep.2019.112255_bib80 article-title: Screening of antidiabetic and antihyperlipidemic potential of oil from Piper longum and piperine with their possible mechanism publication-title: Expert Opin. Pharmacother. doi: 10.1517/14656566.2013.815725 – volume: 8 start-page: 1 issue: 1 year: 2011 ident: 10.1016/j.jep.2019.112255_bib187 article-title: Antioxidant activity of combined ethanolic extract of Eclipta alba and Piper longum Linn publication-title: J. Complement. Integr. Med. doi: 10.2202/1553-3840.1591 – volume: 13 start-page: 143 issue: 02 year: 2011 ident: 10.1016/j.jep.2019.112255_bib101 article-title: Two new amides with cytotoxic activity from the fruits of Piper longum publication-title: J. Asian Nat. Prod. Res. doi: 10.1080/10286020.2010.546789 – volume: 27 start-page: 124 issue: 1 year: 2017 ident: 10.1016/j.jep.2019.112255_bib148 article-title: Natural products assessed in animal models for orofacial pain–a systematic review publication-title: Rev. Bras. Farmacognosia doi: 10.1016/j.bjp.2016.06.005 – volume: 18 start-page: 17 issue: 1 year: 1980 ident: 10.1016/j.jep.2019.112255_bib34 article-title: Medicinal species of Piper, pharmacognostic delimitation publication-title: J. Crude. Drug. Res. doi: 10.3109/13880208009065171 – volume: 12 issue: 2 year: 2017 ident: 10.1016/j.jep.2019.112255_bib163 article-title: Anthelmintic potential of thymoquinone and curcumin on Fasciola gigantica publication-title: PLoS One doi: 10.1371/journal.pone.0171267 – volume: 44 start-page: 15944 issue: 48 year: 2005 ident: 10.1016/j.jep.2019.112255_bib79 article-title: Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells publication-title: Biochem doi: 10.1021/bi050941u – volume: 33 start-page: 307 issue: 2 year: 2012 ident: 10.1016/j.jep.2019.112255_bib81 article-title: Anti-inflammatory activity of two varieties of Pippali (Piper longum Linn.) publication-title: Ayu doi: 10.4103/0974-8520.105258 – volume: 34 start-page: 73 issue: 1 year: 1997 ident: 10.1016/j.jep.2019.112255_bib137 article-title: Characterisation of chemical constituents of Indian long pepper (Piper longum L.) publication-title: J. Food Sci. Technol. – volume: 49 start-page: 1069 issue: 4 year: 1998 ident: 10.1016/j.jep.2019.112255_bib117 article-title: Polyphenols and alkaloids from Piper species publication-title: Phytochemistry doi: 10.1016/S0031-9422(98)00208-8 – ident: 10.1016/j.jep.2019.112255_bib165 – volume: 56 start-page: 287 issue: 4 year: 2005 ident: 10.1016/j.jep.2019.112255_bib8 article-title: Phenolic contents and antioxidant activity of some food and medicinal plants publication-title: Int. J. Food Sci. Nutr. doi: 10.1080/09637480500146606 – volume: 75 start-page: 333 issue: 3 year: 2018 ident: 10.1016/j.jep.2019.112255_bib46 article-title: In vitro acaricidal activity of Piper nigrum and Piper longum fruit extracts and their active components against Rhipicephalus (Boophilus) microplus ticks publication-title: Exp. Appl. Acarol. doi: 10.1007/s10493-018-0268-5 – volume: 3 start-page: 1078 issue: 12 year: 2009 ident: 10.1016/j.jep.2019.112255_bib130 article-title: Antioxidant and antihepatotoxic activities of ethanolic crude extract of Melia azedarach and Piper longum publication-title: J.M.P.R. – volume: 68 start-page: 211 issue: 1 year: 2014 ident: 10.1016/j.jep.2019.112255_bib12 article-title: Occurrence of piperidine alkaloids in Piper species collected in different areas publication-title: J. Nat. Med. doi: 10.1007/s11418-013-0773-0 – start-page: 15 year: 1980 ident: 10.1016/j.jep.2019.112255_bib73 article-title: Search for anthelmintics of plant origin: activities of volatile principles of Acorus calamus and Piper longum against Ascaris lumbricoides, 4 – volume: 1 start-page: 5 issue: 1 year: 2011 ident: 10.1016/j.jep.2019.112255_bib125 article-title: Bioenhancers from mother nature and their applicability in modern medicine publication-title: Int. J. Appl. Basic. Med. Res. doi: 10.4103/2229-516X.81972 – volume: 10 start-page: 333 issue: 2 year: 2018 ident: 10.1016/j.jep.2019.112255_bib74 article-title: Anthelmintic activity of fruit extract and fractions of Piper longum L. In vitro publication-title: Pharmacog. J. doi: 10.5530/pj.2018.2.57 – volume: 153 start-page: 674 issue: 3 year: 2014 ident: 10.1016/j.jep.2019.112255_bib51 article-title: Cytochrome P450 inhibitory potential and RP-HPLC standardization of trikatu—a Rasayana from Indian Ayurveda publication-title: J. Ethnopharmacol. doi: 10.1016/j.jep.2014.03.023 – volume: 6 start-page: 213 issue: 2 year: 2014 ident: 10.1016/j.jep.2019.112255_bib131 article-title: Phytochemical and antimicrobial studies of medicinal plant piper longum linn. I.J.P.P.R. – volume: 96 start-page: 801 issue: 9 year: 2016 ident: 10.1016/j.jep.2019.112255_bib138 article-title: Towards green synthesis of nanoparticles: from bio-assisted sources to benign solvents. A review publication-title: Int. J. Environ. Anal. Chem. – volume: 34 start-page: 2891 issue: 22 year: 2009 ident: 10.1016/j.jep.2019.112255_bib91 article-title: Chemical constituents from Piper longum publication-title: Zhongguo Zhongyao Zazhi – volume: 34 start-page: 115 year: 2014 ident: 10.1016/j.jep.2019.112255_bib126 article-title: Evaluation of antioxidant, antibacterial and cytotoxic effects of green synthesized silver nanoparticles by Piper longum fruit publication-title: Mater. Sci. Eng. C. doi: 10.1016/j.msec.2013.08.039 – volume: 46 start-page: 320 year: 2007 ident: 10.1016/j.jep.2019.112255_bib15 article-title: Fate of embelin in pippalyadi yoga, an ayurvedic oral contraceptive: structure of embelin-borax complex and evaluation of anti-fertility activity publication-title: Indian J. Chem. B – volume: 74 issue: 09 year: 2008 ident: 10.1016/j.jep.2019.112255_bib64 article-title: Anti-stress, nootropic and anticonvulsant potential of fruit extracts of Piper longum L publication-title: Planta Med. doi: 10.1055/s-0028-1084242 |
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| Snippet | Piper longum, commonly referred as ‘Pippali’, has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic,... Piper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian countries as an analgesic,... Ethnopharmacological relevance Piper longum, commonly referred as 'Pippali', has found its traditional use in India, Malaysia, Singapore and other South Asian... |
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| SubjectTerms | alkaloids analgesics anthelmintics antioxidants asthma childbirth contraceptives Culicidae dementia diabetes epilepsy essential oils Ethnopharmacology - methods Ethnopharmacology - trends fever flavonoids glycemic effect guidelines hemorrhage Humans immunostimulants India indigenous knowledge larvicides leprosy Malaysia Medicine, Traditional - methods pharmacokinetics Pharmacology Phytochemistry Piper - chemistry Piper longum Plant Extracts - pharmacology Plant Extracts - therapeutic use rheumatoid arthritis secondary metabolites Singapore sleep disorders spleen steroids surveys systematic review toxicology Traditional evidence traditional medicine Translational Medical Research - methods Translational Medical Research - trends |
| Title | A systematic review on Piper longum L.: Bridging traditional knowledge and pharmacological evidence for future translational research |
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