Circular RNA circ-102,166 acts as a sponge of miR-182 and miR-184 to suppress hepatocellular carcinoma proliferation and invasion

• Published in: Cellular oncology (Dordrecht) Vol. 44; no. 2; pp. 279 - 295
• Main Authors: Li, Rong, Deng, Yinan, Liang, Jinliang, Hu, Zhongying, Li, Xuejiao, Liu, Huanyi, Wang, Guoying, Fu, Binsheng, Zhang, Tong, Zhang, Qi, Yang, Yang, Chen, Guihua, Liu, Wei
• Format: Journal Article
• Language: English
• Published: Dordrecht Springer Netherlands 01.04.2021; Springer Nature B.V
• Subjects: Biomedical and Life Sciences; Biomedicine; c-Myc protein; Cancer Research; Cell proliferation; Circular RNA; Flow cytometry; FOXO3 protein; Hepatocellular carcinoma; Immunoprecipitation; Liver cancer; Localization; Molecular modelling; Myc protein; Northern blotting; Oncology; Original Paper; Pathology; Ribonuclease; Ribonucleic acid; RNA; Tumorigenicity; Western blotting; Wound healing; Xenografts; miR-182; Hepatocellular carcinoma; Circ-102,166; miR-184; Proliferation; Invasion

Purpose Multiple circular RNAs (circRNAs) have been reported to be dysregulated in hepatocellular carcinoma (HCC). However, their functions and modes of action are still largely unclear. Identifying key circRNAs and revealing their potential functions and molecular mechanisms is considered important...