Optimizing congenital cytomegalovirus detection by pool testing in saliva by a rapid molecular test

• Published in: European journal of pediatrics Vol. 182; no. 11; pp. 5131 - 5136
• Main Authors: Izquierdo, Giannina, Farfan, Mauricio J, Villavicencio, Leonel, Montecinos, Luisa, Tarque, Felipe, Acevedo, William, Reyes, Roberto, Guerra, Carolina, Araya, Leslie, Sepúlveda, Belén, Cabrera, Camila, Medina, Pamela, Mendez, Jocelyn, Mardones, Elieder, Torres, Juan P
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.11.2023; Springer Nature B.V
• Subjects: Congenital infection; Cost analysis; Cytomegalovirus; Cytomegalovirus - genetics; Cytomegalovirus Infections - diagnosis; Hearing loss; Humans; Infant; Infant, Newborn; Medicine; Medicine & Public Health; Neonatal Screening - methods; Neonates; Pediatrics; Polymerase chain reaction; Real-Time Polymerase Chain Reaction - methods; Saliva; Urine; Congenital cytomegalovirus; Screening; Loop-mediated isothermal amplification (LAMP); Saliva; Pool-testing

Universal congenital cytomegalovirus (cCMV) screening in saliva is increasingly recommended. The aim of our study was to correlate the performance of a point-of-care rapid molecular test with CMV real time PCR (CMV RT-PCR) detection, using saliva pool-testing in newborns under a universal screening...