Differential inhibition of α-synuclein oligomeric and fibrillar assembly in parkinson's disease model by cinnamon extract - Shaltiel-Karyo, Ronit; Davidi, Dan; Frenkel-Pinter, Moran; Ovadia, Michael; Segal, Daniel; Gazit, Ehud (Biochimica et biophysica acta, 2012)
Keywords: Aggregation inhibitor; alpha-Synuclein - genetics; alpha-Synuclein - metabolism; amyloid; Amyloid - antagonists & inhibitors; Amyloid - genetics; Amyloid - metabolism; Animals; Animals, Genetically Modified; brain; CHO Cells; Cinnamomum zeylanicum - chemistry; cinnamon; Cinnamon extract; confocal microscopy; Cricetinae; Cricetulus; disease models; Disease Models, Animal; Down-Regulation - drug effects; Down-Regulation - genetics; Drosophila; Drosophila - genetics; Drosophila model for Parkinson; Female; Humans; Male; mutants; Parkinson disease; Parkinson Disease - drug therapy; Parkinson Disease - genetics; Parkinson Disease - metabolism; Parkinson Disease - pathology; Parkinson's disease; Phytotherapy - methods; Plant Extracts - therapeutic use; polypeptides; Protein Multimerization - drug effects; Protein Multimerization - genetics; protein secondary structure; spectroscopy; Western blotting; α-synuclein; Aggregation inhibitor; Parkinson's disease; Drosophila model for Parkinson; α-synuclein; Cinnamon extract