Catalpol ameliorates endothelial dysfunction and inflammation in diabetic nephropathy via suppression of RAGE/RhoA/ROCK signaling pathway - Shu, Anmei; Du, Qiu; Chen, Jing; Gao, Yuyan; Zhu, Yihui; Lv, Gaohong; Lu, Jinfu; Chen, Yuping; Xu, Huiqin (Chemico-biological interactions, 2021)
Keywords: AGEs; Animals; Catalpol; Diabetes Mellitus, Experimental - complications; Diabetes Mellitus, Experimental - drug therapy; Diabetes Mellitus, Experimental - metabolism; Diabetic Nephropathies - drug therapy; Diabetic Nephropathies - metabolism; Diabetic Nephropathies - pathology; Diabetic nephropathy; Endothelial Cells - drug effects; Endothelial Cells - metabolism; Endothelial dysfunction; Glycation End Products, Advanced - metabolism; Inflammation; Inflammation - drug therapy; Inflammation - metabolism; Iridoid Glucosides - pharmacology; Iridoid Glucosides - therapeutic use; Male; Mice; Mice, Inbred C57BL; RAGE/RhoA/ROCK pathway; Receptor for Advanced Glycation End Products - metabolism; rho-Associated Kinases - metabolism; rhoA GTP-Binding Protein - metabolism; Signal Transduction - drug effects; Endothelial dysfunction; Diabetic nephropathy; Inflammation; AGEs; Catalpol; RAGE/RhoA/ROCK pathway