CD36 promotes adipocyte differentiation and adipogenesis

• Published in: Biochimica et biophysica acta Vol. 1820; no. 7; pp. 949 - 956
• Main Authors: Christiaens, Valerie, Van Hul, Matthias, Lijnen, H. Roger, Scroyen, Ilse
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.07.2012
• Subjects: (Pre)adipocyte; 3T3 Cells; adipocytes; Adipocytes - cytology; Adipocytes - metabolism; Adipogenesis; Adipogenesis - physiology; Adipose tissue; Animals; Body Weight; CD36; CD36 Antigens - chemistry; CD36 Antigens - physiology; Cell Differentiation; collagen; Diet, High-Fat - adverse effects; gene silencing; genes; macrophages; Male; membrane glycoproteins; metabolic diseases; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; obesity; Obesity - etiology; Obesity - prevention & control; pathogenesis; (Pre)adipocyte; Adipose tissue; CD36; Adipogenesis

CD36 is a membrane glycoprotein, contributing to the pathogenesis of metabolic disorders, like obesity, which has become a major health concern worldwide. A potential functional role of the scavenger receptor CD36 was investigated in in vitro adipocyte differentiation and in vivo adipogenesis. Durin...