CXCL9 and its Receptor CXCR3, an Important Link Between Inflammation and Cardiovascular Risks in RA Patients
Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis. CXCL9 contributes to multi aspects of inflammatory reactions associated with the pathogenesis of CVD. In the current study, we evaluated the asso...
Saved in:
Published in | Inflammation Vol. 46; no. 6; pp. 2374 - 2385 |
---|---|
Main Authors | , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.12.2023
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis. CXCL9 contributes to multi aspects of inflammatory reactions associated with the pathogenesis of CVD. In the current study, we evaluated the association of plasma CXCL9 and CXCR3 gene expression with Cardiovascular risk factors in RA patients for the first time. Thirty newly diagnosed, 30 on-treatment RA patients, and 30 healthy subjects were recruited in this study. The plasma concentration of CXCL9 and CXCR3 gene expression were measured using ELISA and Real-Time PCR, respectively. The CVD risk was evaluated using Framingham Risk Score (FRS) and Systematic Coronary Risk Evaluation (SCORE). The plasma levels of CXCL9 were significantly higher in the newly diagnosed and on-treatment RA patients compared to the control group (
P
< 0.0001 and
P
< 0.001, respectively). Also, The CXCR3 gene expression was strongly elevated in newly diagnosed and on-treatment patients (
P
< 0.001 and
P
< 0.01, respectively). The CXCL9 and CXCR3 were significantly associated with RA disease activity (
P
= 0.0005, r = 0.436;
P
= 0.0002, r = 0.463, respectively). The FRS was remarkably higher in newly diagnosed and on-treatment patients (
P
= 0.014 and
P
= 0.035, respectively). The CXCR3 gene expression significantly correlated with age, systolic blood pressure, FRS, and SCORE (
P
= 0.020, r = 0.298;
P
= 0.006, r = 0.346;
P
= 0.006, r = 0.349;
P
= 0.007, r = 0.341, respectively). The CXCL9 plasma concentration had a significant negative correlation with plasma HDL and LDL levels (
P
= 0.033, r = -0.275;
P
= 0.021, r = -0.296, respectively). CXCL9 and CXCR3 correlates with different variables of CVD in RA. |
---|---|
AbstractList | Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis. CXCL9 contributes to multi aspects of inflammatory reactions associated with the pathogenesis of CVD. In the current study, we evaluated the association of plasma CXCL9 and CXCR3 gene expression with Cardiovascular risk factors in RA patients for the first time. Thirty newly diagnosed, 30 on-treatment RA patients, and 30 healthy subjects were recruited in this study. The plasma concentration of CXCL9 and CXCR3 gene expression were measured using ELISA and Real-Time PCR, respectively. The CVD risk was evaluated using Framingham Risk Score (FRS) and Systematic Coronary Risk Evaluation (SCORE). The plasma levels of CXCL9 were significantly higher in the newly diagnosed and on-treatment RA patients compared to the control group (P < 0.0001 and P < 0.001, respectively). Also, The CXCR3 gene expression was strongly elevated in newly diagnosed and on-treatment patients (P < 0.001 and P < 0.01, respectively). The CXCL9 and CXCR3 were significantly associated with RA disease activity (P = 0.0005, r = 0.436; P = 0.0002, r = 0.463, respectively). The FRS was remarkably higher in newly diagnosed and on-treatment patients (P = 0.014 and P = 0.035, respectively). The CXCR3 gene expression significantly correlated with age, systolic blood pressure, FRS, and SCORE (P = 0.020, r = 0.298; P = 0.006, r = 0.346; P = 0.006, r = 0.349; P = 0.007, r = 0.341, respectively). The CXCL9 plasma concentration had a significant negative correlation with plasma HDL and LDL levels (P = 0.033, r = -0.275; P = 0.021, r = -0.296, respectively). CXCL9 and CXCR3 correlates with different variables of CVD in RA. Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis. CXCL9 contributes to multi aspects of inflammatory reactions associated with the pathogenesis of CVD. In the current study, we evaluated the association of plasma CXCL9 and CXCR3 gene expression with Cardiovascular risk factors in RA patients for the first time. Thirty newly diagnosed, 30 on-treatment RA patients, and 30 healthy subjects were recruited in this study. The plasma concentration of CXCL9 and CXCR3 gene expression were measured using ELISA and Real-Time PCR, respectively. The CVD risk was evaluated using Framingham Risk Score (FRS) and Systematic Coronary Risk Evaluation (SCORE). The plasma levels of CXCL9 were significantly higher in the newly diagnosed and on-treatment RA patients compared to the control group ( P < 0.0001 and P < 0.001, respectively). Also, The CXCR3 gene expression was strongly elevated in newly diagnosed and on-treatment patients ( P < 0.001 and P < 0.01, respectively). The CXCL9 and CXCR3 were significantly associated with RA disease activity ( P = 0.0005, r = 0.436; P = 0.0002, r = 0.463, respectively). The FRS was remarkably higher in newly diagnosed and on-treatment patients ( P = 0.014 and P = 0.035, respectively). The CXCR3 gene expression significantly correlated with age, systolic blood pressure, FRS, and SCORE ( P = 0.020, r = 0.298; P = 0.006, r = 0.346; P = 0.006, r = 0.349; P = 0.007, r = 0.341, respectively). The CXCL9 plasma concentration had a significant negative correlation with plasma HDL and LDL levels ( P = 0.033, r = -0.275; P = 0.021, r = -0.296, respectively). CXCL9 and CXCR3 correlates with different variables of CVD in RA. |
Author | Roghani, Seyed Askar Shamsi, Afsaneh Soufivand, Parviz Salari, Nader Taghadosi, Mahdi Pournazari, Mehran Abdan, Zahra Bahrehmand, Fariborz Vafaei, Ali Soroush, Masood Ghasemzade |
Author_xml | – sequence: 1 givenname: Afsaneh orcidid: 0000-0002-5945-2381 surname: Shamsi fullname: Shamsi, Afsaneh organization: Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences – sequence: 2 givenname: Seyed Askar orcidid: 0000-0003-0758-0653 surname: Roghani fullname: Roghani, Seyed Askar organization: Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences, Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences – sequence: 3 givenname: Zahra orcidid: 0000-0003-3209-5262 surname: Abdan fullname: Abdan, Zahra organization: Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences – sequence: 4 givenname: Parviz orcidid: 0000-0001-5517-791X surname: Soufivand fullname: Soufivand, Parviz organization: Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences – sequence: 5 givenname: Mehran orcidid: 0000-0003-3542-3049 surname: Pournazari fullname: Pournazari, Mehran organization: Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences – sequence: 6 givenname: Fariborz orcidid: 0000-0003-3866-6847 surname: Bahrehmand fullname: Bahrehmand, Fariborz organization: Medical Biology Research Center, Kermanshah University of Medical Sciences – sequence: 7 givenname: Ali orcidid: 0009-0004-7381-5283 surname: Vafaei fullname: Vafaei, Ali organization: Department of Medical Biotechnology, Faculty of Medicine, Kermanshah University of Medical Sciences – sequence: 8 givenname: Nader orcidid: 0000-0003-3550-405X surname: Salari fullname: Salari, Nader organization: Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences – sequence: 9 givenname: Masood Ghasemzade orcidid: 0000-0002-6494-9990 surname: Soroush fullname: Soroush, Masood Ghasemzade organization: Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences – sequence: 10 givenname: Mahdi orcidid: 0000-0002-3516-0130 surname: Taghadosi fullname: Taghadosi, Mahdi email: mtaghad@gmail.com organization: Immunology Department, Faculty of Medicine, Kermanshah University of Medical Sciences |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/37542661$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kU1LHTEYhUNR6tX2D3RRAm5cODYfk2Sy1MEvuNByaaG7kMy8t4zOJLdJRvHfm3qtggsXIXDynJOX9-yjHR88IPSFkhNKiPqWKFGCV4SVQ5umrsQHtKBC8YoJJXfQgnBJKq612kP7Kd0QQhrd8I9ojytRMynpAo3t73apsfU9HnLCK-hgk0PERV7x46Lj62kTYrY-4-Xgb_EZ5HuAIvv1aKfJ5iH4J3trYz-EO5u6ebQRr4Z0m_Dg8eoU_ygU-Jw-od21HRN8fr4P0K-L85_tVbX8fnndni6rrqY6Vw5qWnMhheyoYk4C4wxUmV6p2jWqB8cdlUy7ntTMCa06QaVYA-3KQhxV_AAdbXM3MfydIWUzDamDcbQewpwMa2qpmVKqKejhG_QmzNGX6QqlOWuI5LpQbEt1MaQUYW02cZhsfDCUmH9dmG0XpnRhnrowopi-PkfPboL-xfJ_-QXgWyCVJ_8H4uvf78Q-Arx1kz0 |
CitedBy_id | crossref_primary_10_3390_cells13110915 crossref_primary_10_18632_aging_205644 crossref_primary_10_3390_cells12232716 crossref_primary_10_1016_j_nucmedbio_2024_108912 |
Cites_doi | 10.1007/s10067-021-05899-x 10.1016/S0140-6736(13)61752-3 10.1186/ar783 10.1042/CS20150666 10.1016/S0195-668X(03)00114-3 10.1038/s41584-022-00771-x 10.1016/j.autrev.2021.102776 10.1093/rheumatology/keac617 10.1186/s12979-020-00178-w 10.1016/j.autrev.2020.102735 10.1136/bmj.k1036 10.1161/01.cir.0000437741.48606.98 10.3390/biomedicines10081938 10.1136/annrheumdis-2016-209775 10.1002/art.20615 10.1016/j.cytogfr.2014.11.009 10.1056/NEJMra2103726 10.1016/j.mpmed.2018.01.008 10.1371/journal.pone.0141394 10.1186/s13075-017-1224-1 10.3389/fmed.2023.1146353 10.12669/pjms.323.9779 10.1093/nar/29.9.e45 10.7326/AITC201901010 10.1002/art.24148 10.1007/s00296-020-04731-0 10.1016/j.gene.2019.03.033 10.1136/ard-2022-223356 10.3389/fphar.2021.765768 10.3390/jcm8050659 10.1111/1756-185X.12589 10.1007/s40744-019-00189-0 10.1172/JCI6993 10.1038/s41584-020-0428-y 10.1016/0021-9681(67)90082-3 10.1136/heartjnl-2015-308953 10.3389/fmed.2021.689698 10.1002/acr.22483 10.1056/NEJM200103223441207 10.1038/s43587-021-00082-y 10.1038/s41584-021-00593-3 10.3899/jrheum.090769 10.1002/art.1780380107 10.1080/08820139.2020.1781160 10.1136/rmdopen-2020-001470 10.1126/science.ade0113 |
ContentType | Journal Article |
Copyright | The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
Copyright_xml | – notice: The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. – notice: 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
DBID | NPM AAYXX CITATION 3V. 7T5 7TO 7U9 7X7 7XB 88E 8AO 8FI 8FJ 8FK ABUWG AFKRA BENPR CCPQU FYUFA GHDGH H94 K9. M0S M1P PQEST PQQKQ PQUKI PRINS 7X8 |
DOI | 10.1007/s10753-023-01884-5 |
DatabaseName | PubMed CrossRef ProQuest Central (Corporate) Immunology Abstracts Oncogenes and Growth Factors Abstracts Virology and AIDS Abstracts Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) ProQuest Pharma Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central ProQuest Central ProQuest One Community College Health Research Premium Collection Health Research Premium Collection (Alumni) AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic |
DatabaseTitle | PubMed CrossRef Virology and AIDS Abstracts Oncogenes and Growth Factors Abstracts ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Pharma Collection ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central ProQuest Health & Medical Complete Health Research Premium Collection ProQuest Medical Library ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) AIDS and Cancer Research Abstracts Immunology Abstracts ProQuest One Academic ProQuest Medical Library (Alumni) ProQuest Central (Alumni) MEDLINE - Academic |
DatabaseTitleList | PubMed MEDLINE - Academic Virology and AIDS Abstracts |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1573-2576 |
EndPage | 2385 |
ExternalDocumentID | 10_1007_s10753_023_01884_5 37542661 |
Genre | Journal Article |
GroupedDBID | --- -53 -5E -5G -BR -EM -Y2 -~C .86 .GJ .VR 06C 06D 0R~ 0VY 1N0 1SB 2.D 203 28- 29I 29~ 2J2 2JN 2JY 2KG 2KM 2LR 2P1 2VQ 2~H 30V 3SX 3V. 4.4 406 408 409 40D 40E 53G 5GY 5QI 5RE 5VS 67Z 6NX 78A 7X7 88E 8AO 8FI 8FJ 8TC 8UJ 95- 95. 95~ 96X AAAVM AABHQ AABYN AAFGU AAHNG AAIAL AAJKR AANXM AANZL AAPBV AARHV AARTL AATNV AATVU AAUYE AAWCG AAYFA AAYIU AAYQN AAYTO ABBBX ABBXA ABDZT ABECU ABELW ABFGW ABFTV ABHLI ABHQN ABJNI ABJOX ABKAS ABKCH ABKTR ABMNI ABMQK ABNWP ABPLI ABPTK ABQBU ABSXP ABTEG ABTKH ABTMW ABULA ABUWG ABWNU ABXPI ACBMV ACBRV ACBYP ACGFS ACHSB ACHXU ACIGE ACIPQ ACKNC ACMDZ ACMLO ACOKC ACOMO ACPRK ACTTH ACUDM ACVWB ACWMK ADBBV ADHHG ADHIR ADIMF ADINQ ADKNI ADKPE ADMDM ADOAH ADOXG ADRFC ADTPH ADURQ ADYFF ADZKW AEBTG AEEQQ AEFIE AEFTE AEGAL AEGNC AEJHL AEJRE AEKMD AENEX AEOHA AEPYU AESKC AESTI AETLH AEVLU AEVTX AEXYK AFEXP AFFNX AFKRA AFLOW AFNRJ AFQWF AFWTZ AFZKB AGAYW AGDGC AGGBP AGGDS AGJBK AGMZJ AGQMX AGWIL AGWZB AGYKE AHAVH AHBYD AHKAY AHMBA AHSBF AHYZX AIAKS AIIXL AILAN AIMYW AITGF AJBLW AJDOV AJRNO AJZVZ AKMHD AKQUC ALMA_UNASSIGNED_HOLDINGS ALWAN AMKLP AMXSW AMYLF AMYQR AOCGG AOSHJ ARMRJ ASPBG AVWKF AXYYD AZFZN B-. BA0 BBWZM BDATZ BENPR BGNMA BPHCQ BVXVI CAG CCPQU COF CS3 CSCUP DDRTE DL5 DNIVK DPUIP DU5 EBD EBLON EBS EIOEI EJD EMB EMOBN EN4 EPAXT ESBYG F5P FEDTE FERAY FFXSO FIGPU FINBP FNLPD FRRFC FSGXE FWDCC FYUFA G-Y G-Z GGCAI GGRSB GJIRD GNWQR GQ6 GQ7 GQ8 GRRUI GXS HF~ HG5 HG6 HMCUK HMJXF HQYDN HRMNR HVGLF HZ~ I09 IHE IJ- IKXTQ ITM IWAJR IXC IZIGR IZQ I~X I~Z J-C J0Z JBSCW JCJTX JZLTJ KDC KOV KOW KPH LAK LLZTM M1P M4Y MA- N2Q NB0 NDZJH NPVJJ NQJWS NU0 O9- O93 O9G O9I O9J OAM OVD P19 P2P P9S PF0 PQQKQ PROAC PSQYO PT4 PT5 Q2X QOK QOR QOS R4E R89 R9I RHV RNI ROL RPX RRX RSV RZC RZE RZK S16 S1Z S26 S27 S28 S37 S3B SAP SBY SCLPG SDE SDH SDM SHX SISQX SJYHP SMD SNE SNPRN SNX SOHCF SOJ SPISZ SRMVM SSLCW SSXJD STPWE SV3 SZ9 SZN T13 T16 TEORI TSG TSK TSV TT1 TUC U2A U9L UG4 UKHRP UNUBA UOJIU UTJUX UZXMN VC2 VFIZW W23 W48 WJK WK6 WK8 Y6R YLTOR Z45 Z7U Z7W Z82 Z83 Z87 Z8O Z8Q Z8V Z8W Z91 ZGI ZMTXR ZOVNA ~A9 ~EX AACDK AAJBT AASML AAYZH ABAKF ACAOD ACDTI ACZOJ AEFQL AEMSY AFBBN AGQEE AGRTI AIGIU ALIPV NPM AAEOY AAQLM AAYXX CITATION H13 7T5 7TO 7U9 7XB 8FK H94 K9. PQEST PQUKI PRINS 7X8 |
ID | FETCH-LOGICAL-c419t-be41435656c172b6e232e7000774b87deb3b1629bd042b597c5165fe1c107b173 |
IEDL.DBID | BENPR |
ISSN | 0360-3997 |
IngestDate | Sat Aug 17 00:57:00 EDT 2024 Tue Oct 22 16:05:30 EDT 2024 Thu Sep 12 16:23:45 EDT 2024 Wed Oct 16 00:38:52 EDT 2024 Sat Dec 16 12:03:35 EST 2023 |
IsDoiOpenAccess | false |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 6 |
Keywords | CVD CXCL9 rheumatoid arthritis CXCR3 |
Language | English |
License | 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c419t-be41435656c172b6e232e7000774b87deb3b1629bd042b597c5165fe1c107b173 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ORCID | 0000-0003-3550-405X 0000-0002-5945-2381 0009-0004-7381-5283 0000-0003-3542-3049 0000-0003-3866-6847 0000-0002-3516-0130 0000-0003-0758-0653 0000-0003-3209-5262 0000-0002-6494-9990 0000-0001-5517-791X |
OpenAccessLink | https://www.researchsquare.com/article/rs-2868920/latest.pdf |
PMID | 37542661 |
PQID | 2893280639 |
PQPubID | 37566 |
PageCount | 12 |
ParticipantIDs | proquest_miscellaneous_2846927778 proquest_journals_2893280639 crossref_primary_10_1007_s10753_023_01884_5 pubmed_primary_37542661 springer_journals_10_1007_s10753_023_01884_5 |
PublicationCentury | 2000 |
PublicationDate | 2023-12-01 |
PublicationDateYYYYMMDD | 2023-12-01 |
PublicationDate_xml | – month: 12 year: 2023 text: 2023-12-01 day: 01 |
PublicationDecade | 2020 |
PublicationPlace | New York |
PublicationPlace_xml | – name: New York – name: United States |
PublicationTitle | Inflammation |
PublicationTitleAbbrev | Inflammation |
PublicationTitleAlternate | Inflammation |
PublicationYear | 2023 |
Publisher | Springer US Springer Nature B.V |
Publisher_xml | – name: Springer US – name: Springer Nature B.V |
References | Choy, Panayi (CR19) 2001; 344 Rudominer (CR44) 2009; 60 Romão, Fonseca (CR2) 2021; 8 Gulati, Farah, Mouyis (CR10) 2018; 46 Figus (CR8) 2021; 20 Desai (CR42) 2015; 67 Bauer (CR3) 2020; 17 England (CR49) 2018; 361 Mahmood (CR28) 2014; 383 Sparks (CR9) 2019; 170 Ruschpler (CR36) 2003; 5 O'Neill (CR40) 2017; 103 Altara (CR23) 2015; 10 Pfaffl (CR25) 2001; 29 Agca (CR13) 2017; 76 Conforti (CR6) 2021; 20 Conroy (CR30) 2003; 24 Smolen (CR45) 2023; 82 Brynedal (CR47) 2023; 10 Wagan (CR37) 2016; 32 Atzeni (CR50) 2021; 17 Al-Jaberi, Simonds, Brescia (CR34) 2022; 62 Frąk (CR12) 2022; 10 Truett, Cornfield, Kannel (CR29) 1967; 20 Lin (CR24) 2019; 8 England (CR15) 2018; 361 Goff (CR27) 2014; 129 Finckh (CR5) 2022; 18 Karami (CR7) 2019; 702 Prevoo (CR26) 1995; 38 Samimi (CR41) 2021; 50 Van Raemdonck (CR35) 2015; 26 Pournazari (CR18) 2022; 41 Mach (CR39) 1999; 104 Almutairi (CR4) 2021; 41 DeMizio, Geraldino-Pardilla (CR16) 2020; 7 Szekanecz, Kim, Koch (CR20) 2003 Santos-Moreno (CR14) 2021; 7 García-Vicuña (CR21) 2004; 50 Altara (CR38) 2016; 130 Kotrych (CR48) 2015; 19 Lu (CR22) 2022; 12 Sayed (CR17) 2021; 1 Bonfante (CR46) 2017; 20 Fearon (CR1) 2022; 18 Semb (CR11) 2020; 16 Gravallese, Firestein (CR33) 2023; 388 Kuan (CR31) 2010; 37 Pandya (CR32) 2017; 19 Matarese (CR43) 2023; 379 RL Rudominer (1884_CR44) 2009; 60 K Van Raemdonck (1884_CR35) 2015; 26 F O'Neill (1884_CR40) 2017; 103 M Gulati (1884_CR10) 2018; 46 F Atzeni (1884_CR50) 2021; 17 J Karami (1884_CR7) 2019; 702 EM Gravallese (1884_CR33) 2023; 388 DJ DeMizio (1884_CR16) 2020; 7 Z Samimi (1884_CR41) 2021; 50 R García-Vicuña (1884_CR21) 2004; 50 JM Pandya (1884_CR32) 2017; 19 R Agca (1884_CR13) 2017; 76 N Sayed (1884_CR17) 2021; 1 X Lu (1884_CR22) 2022; 12 R Altara (1884_CR38) 2016; 130 BR England (1884_CR49) 2018; 361 W Frąk (1884_CR12) 2022; 10 JS Smolen (1884_CR45) 2023; 82 K Almutairi (1884_CR4) 2021; 41 L Al-Jaberi (1884_CR34) 2022; 62 AG Semb (1884_CR11) 2020; 16 D Kotrych (1884_CR48) 2015; 19 A Finckh (1884_CR5) 2022; 18 Z Szekanecz (1884_CR20) 2003 AA Wagan (1884_CR37) 2016; 32 DC Goff Jr (1884_CR27) 2014; 129 RJ Desai (1884_CR42) 2015; 67 JA Sparks (1884_CR9) 2019; 170 MW Pfaffl (1884_CR25) 2001; 29 J Truett (1884_CR29) 1967; 20 U Fearon (1884_CR1) 2022; 18 ME Bauer (1884_CR3) 2020; 17 P Santos-Moreno (1884_CR14) 2021; 7 FA Figus (1884_CR8) 2021; 20 CF Lin (1884_CR24) 2019; 8 B Brynedal (1884_CR47) 2023; 10 A Conforti (1884_CR6) 2021; 20 F Mach (1884_CR39) 1999; 104 EH Choy (1884_CR19) 2001; 344 RM Conroy (1884_CR30) 2003; 24 SS Mahmood (1884_CR28) 2014; 383 WP Kuan (1884_CR31) 2010; 37 HDL Bonfante (1884_CR46) 2017; 20 M Pournazari (1884_CR18) 2022; 41 R Altara (1884_CR23) 2015; 10 P Ruschpler (1884_CR36) 2003; 5 VC Romão (1884_CR2) 2021; 8 BR England (1884_CR15) 2018; 361 G Matarese (1884_CR43) 2023; 379 M Prevoo (1884_CR26) 1995; 38 |
References_xml | – volume: 41 start-page: 265 year: 2022 end-page: 270 ident: CR18 article-title: Increased plasma levels of CCL20 in peripheral blood of rheumatoid arthritis patients and its association with clinical and laboratory parameters publication-title: Clinical Rheumatology doi: 10.1007/s10067-021-05899-x contributor: fullname: Pournazari – volume: 383 start-page: 999 issue: 9921 year: 2014 end-page: 1008 ident: CR28 article-title: The Framingham Heart Study and the epidemiology of cardiovascular disease: a historical perspective publication-title: Lancet doi: 10.1016/S0140-6736(13)61752-3 contributor: fullname: Mahmood – volume: 5 start-page: R241 year: 2003 ident: CR36 article-title: High CXCR3 expression in synovial mast cells associated with CXCL9 and CXCL10 expression in inflammatory synovial tissues of patients with rheumatoid arthritis publication-title: Arthritis Research & Therapy doi: 10.1186/ar783 contributor: fullname: Ruschpler – volume: 130 start-page: 463 issue: 7 year: 2016 end-page: 478 ident: CR38 article-title: Emerging importance of chemokine receptor CXCR3 and its ligands in cardiovascular diseases publication-title: Clinical Science doi: 10.1042/CS20150666 contributor: fullname: Altara – volume: 24 start-page: 987 issue: 11 year: 2003 end-page: 1003 ident: CR30 article-title: Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project publication-title: European Heart Journal doi: 10.1016/S0195-668X(03)00114-3 contributor: fullname: Conroy – volume: 18 start-page: 398 issue: 7 year: 2022 end-page: 414 ident: CR1 article-title: Cellular metabolic adaptations in rheumatoid arthritis and their therapeutic implications publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-022-00771-x contributor: fullname: Fearon – volume: 20 issue: 4 year: 2021 ident: CR8 article-title: Rheumatoid arthritis: Extra-articular manifestations and comorbidities publication-title: Autoimmunity Reviews doi: 10.1016/j.autrev.2021.102776 contributor: fullname: Figus – volume: 62 start-page: 2594 issue: 7 year: 2022 end-page: 2600 ident: CR34 article-title: CCL24, CXCL9 and CXCL10 are increased in synovial fluid in patients with juvenile idiopathic arthritis requiring advanced treatment publication-title: Rheumatology doi: 10.1093/rheumatology/keac617 contributor: fullname: Brescia – volume: 17 start-page: 6 year: 2020 ident: CR3 article-title: Accelerated immunosenescence in rheumatoid arthritis: impact on clinical progression publication-title: Immunity & Ageing doi: 10.1186/s12979-020-00178-w contributor: fullname: Bauer – volume: 20 issue: 2 year: 2021 ident: CR6 article-title: Beyond the joints, the extra-articular manifestations in rheumatoid arthritis publication-title: Autoimmunity Reviews doi: 10.1016/j.autrev.2020.102735 contributor: fullname: Conforti – volume: 361 year: 2018 ident: CR15 article-title: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications publication-title: BMJ doi: 10.1136/bmj.k1036 contributor: fullname: England – volume: 129 start-page: S49 issue: 25_suppl_2 year: 2014 end-page: S73 ident: CR27 article-title: 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines publication-title: Circulation doi: 10.1161/01.cir.0000437741.48606.98 contributor: fullname: Goff – year: 2003 ident: CR20 article-title: Chemokines and chemokine receptors in rheumatoid arthritis publication-title: Seminars in immunology contributor: fullname: Koch – volume: 10 start-page: 1938 issue: 8 year: 2022 ident: CR12 article-title: Pathophysiology of cardiovascular diseases: new insights into molecular mechanisms of atherosclerosis, arterial hypertension, and coronary artery disease publication-title: Biomedicines doi: 10.3390/biomedicines10081938 contributor: fullname: Frąk – volume: 76 start-page: 17 issue: 1 year: 2017 end-page: 28 ident: CR13 article-title: EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update publication-title: Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2016-209775 contributor: fullname: Agca – volume: 50 start-page: 3866 issue: 12 year: 2004 end-page: 3877 ident: CR21 article-title: CC and CXC chemokine receptors mediate migration, proliferation, and matrix metalloproteinase production by fibroblast-like synoviocytes from rheumatoid arthritis patients publication-title: Arthritis & Rheumatism doi: 10.1002/art.20615 contributor: fullname: García-Vicuña – volume: 361 start-page: k1036 year: 2018 ident: CR49 article-title: Increased cardiovascular risk in rheumatoid arthritis: mechanisms and implications publication-title: The BMJ doi: 10.1136/bmj.k1036 contributor: fullname: England – volume: 26 start-page: 311 issue: 3 year: 2015 end-page: 327 ident: CR35 article-title: CXCR3 ligands in disease and therapy publication-title: Cytokine & Growth Factor Reviews doi: 10.1016/j.cytogfr.2014.11.009 contributor: fullname: Van Raemdonck – volume: 388 start-page: 529 issue: 6 year: 2023 end-page: 542 ident: CR33 article-title: Rheumatoid arthritis—Common origins, divergent mechanisms publication-title: New England Journal of Medicine doi: 10.1056/NEJMra2103726 contributor: fullname: Firestein – volume: 46 start-page: 211 issue: 4 year: 2018 end-page: 215 ident: CR10 article-title: Clinical features of rheumatoid arthritis publication-title: Medicine doi: 10.1016/j.mpmed.2018.01.008 contributor: fullname: Mouyis – volume: 10 issue: 10 year: 2015 ident: CR23 article-title: Left ventricular dysfunction and CXCR3 ligands in hypertension: from animal experiments to a population-based pilot study publication-title: PLoS ONE doi: 10.1371/journal.pone.0141394 contributor: fullname: Altara – volume: 19 start-page: 20 issue: 1 year: 2017 ident: CR32 article-title: Blood chemokine profile in untreated early rheumatoid arthritis: CXCL10 as a disease activity marker publication-title: Arthritis Research & Therapy doi: 10.1186/s13075-017-1224-1 contributor: fullname: Pandya – volume: 19 start-page: 3037 issue: 16 year: 2015 end-page: 3040 ident: CR48 article-title: Lack of association between CXCL9 and CXCL10 gene polymorphisms and the outcome of rheumatoid arthritis treatment with methotrexate publication-title: European Review for Medical and Pharmacological Sciences contributor: fullname: Kotrych – volume: 10 start-page: 1146353 year: 2023 ident: CR47 article-title: Molecular signature of methotrexate response among rheumatoid arthritis patients publication-title: Frontiers in Medicine doi: 10.3389/fmed.2023.1146353 contributor: fullname: Brynedal – volume: 32 start-page: 534 issue: 3 year: 2016 ident: CR37 article-title: Cardiovascular risk score in rheumatoid arthritis publication-title: Pakistan Journal of Medical Sciences doi: 10.12669/pjms.323.9779 contributor: fullname: Wagan – volume: 29 start-page: e45 issue: 9 year: 2001 end-page: e45 ident: CR25 article-title: A new mathematical model for relative quantification in real-time RT–PCR publication-title: Nucleic Acids Research doi: 10.1093/nar/29.9.e45 contributor: fullname: Pfaffl – volume: 170 start-page: Itc1 issue: 1 year: 2019 end-page: Itc16 ident: CR9 article-title: Rheumatoid arthritis publication-title: Annals of Internal Medicine doi: 10.7326/AITC201901010 contributor: fullname: Sparks – volume: 60 start-page: 22 issue: 1 year: 2009 end-page: 29 ident: CR44 article-title: Independent association of rheumatoid arthritis with increased left ventricular mass but not with reduced ejection fraction publication-title: Arthritis & Rheumatism doi: 10.1002/art.24148 contributor: fullname: Rudominer – volume: 41 start-page: 863 issue: 5 year: 2021 end-page: 877 ident: CR4 article-title: The global prevalence of rheumatoid arthritis: a meta-analysis based on a systematic review publication-title: Rheumatology international doi: 10.1007/s00296-020-04731-0 contributor: fullname: Almutairi – volume: 702 start-page: 8 year: 2019 end-page: 16 ident: CR7 article-title: Genetic implications in the pathogenesis of rheumatoid arthritis; an updated review publication-title: Gene doi: 10.1016/j.gene.2019.03.033 contributor: fullname: Karami – volume: 82 start-page: 3 issue: 1 year: 2023 end-page: 18 ident: CR45 article-title: EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update publication-title: Annals of the Rheumatic Diseases doi: 10.1136/ard-2022-223356 contributor: fullname: Smolen – volume: 12 start-page: 3830 year: 2022 ident: CR22 article-title: The role of CXC chemokines in cardiovascular diseases publication-title: Frontiers in Pharmacology doi: 10.3389/fphar.2021.765768 contributor: fullname: Lu – volume: 18 start-page: 591 issue: 10 year: 2022 end-page: 602 ident: CR5 article-title: Global epidemiology of rheumatoid arthritis publication-title: Nature Reviews Rheumatology contributor: fullname: Finckh – volume: 8 start-page: 659 issue: 5 year: 2019 ident: CR24 article-title: Potential effects of CXCL9 and CCL20 on cardiac fibrosis in patients with myocardial infarction and isoproterenol-treated rats publication-title: Journal of Clinical Medicine doi: 10.3390/jcm8050659 contributor: fullname: Lin – volume: 20 start-page: 1958 issue: 12 year: 2017 end-page: 1964 ident: CR46 article-title: CCL 2, CXCL 8, CXCL 9 and CXCL 10 serum levels increase with age but are not altered by treatment with hydroxychloroquine in patients with osteoarthritis of the knees publication-title: International Journal of Rheumatic Diseases doi: 10.1111/1756-185X.12589 contributor: fullname: Bonfante – volume: 7 start-page: 19 issue: 1 year: 2020 end-page: 33 ident: CR16 article-title: Autoimmunity and inflammation link to cardiovascular disease risk in rheumatoid arthritis publication-title: Rheumatology and Therapy doi: 10.1007/s40744-019-00189-0 contributor: fullname: Geraldino-Pardilla – volume: 104 start-page: 1041 issue: 8 year: 1999 end-page: 1050 ident: CR39 article-title: Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells publication-title: The Journal of Clinical Investigation doi: 10.1172/JCI6993 contributor: fullname: Mach – volume: 16 start-page: 361 issue: 7 year: 2020 end-page: 379 ident: CR11 article-title: Atherosclerotic cardiovascular disease prevention in rheumatoid arthritis publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-020-0428-y contributor: fullname: Semb – volume: 20 start-page: 511 issue: 7 year: 1967 end-page: 524 ident: CR29 article-title: A multivariate analysis of the risk of coronary heart disease in Framingham publication-title: Journal of Chronic Diseases doi: 10.1016/0021-9681(67)90082-3 contributor: fullname: Kannel – volume: 103 start-page: 766 issue: 10 year: 2017 end-page: 773 ident: CR40 article-title: Anti-inflammatory treatment improves high-density lipoprotein function in rheumatoid arthritis publication-title: Heart doi: 10.1136/heartjnl-2015-308953 contributor: fullname: O'Neill – volume: 8 start-page: 689698 year: 2021 ident: CR2 article-title: Etiology and risk factors for rheumatoid arthritis: a state-of-the-art review publication-title: Frontiers in Medicine doi: 10.3389/fmed.2021.689698 contributor: fullname: Fonseca – volume: 67 start-page: 457 issue: 4 year: 2015 end-page: 466 ident: CR42 article-title: Disease-modifying antirheumatic drug use and the risk of incident hyperlipidemia in patients with early rheumatoid arthritis: a retrospective cohort study publication-title: Arthritis Care & Research doi: 10.1002/acr.22483 contributor: fullname: Desai – volume: 344 start-page: 907 issue: 12 year: 2001 end-page: 916 ident: CR19 article-title: Cytokine pathways and joint inflammation in rheumatoid arthritis publication-title: New England Journal of Medicine doi: 10.1056/NEJM200103223441207 contributor: fullname: Panayi – volume: 1 start-page: 598 issue: 7 year: 2021 end-page: 615 ident: CR17 article-title: An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging publication-title: Nature Aging doi: 10.1038/s43587-021-00082-y contributor: fullname: Sayed – volume: 17 start-page: 270 issue: 5 year: 2021 end-page: 290 ident: CR50 article-title: Cardiovascular effects of approved drugs for rheumatoid arthritis publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-021-00593-3 contributor: fullname: Atzeni – volume: 37 start-page: 257 issue: 2 year: 2010 end-page: 264 ident: CR31 article-title: CXCL 9 and CXCL 10 as Sensitive markers of disease activity in patients with rheumatoid arthritis publication-title: The Journal of Rheumatology doi: 10.3899/jrheum.090769 contributor: fullname: Kuan – volume: 38 start-page: 44 issue: 1 year: 1995 end-page: 48 ident: CR26 article-title: Modified disease activity scores that include twenty-eight-joint counts development and validation in a prospective longitudinal study of patients with rheumatoid arthritis publication-title: Arthritis & Rheumatism: Official Journal of the American College of Rheumatology doi: 10.1002/art.1780380107 contributor: fullname: Prevoo – volume: 50 start-page: 597 issue: 6 year: 2021 end-page: 608 ident: CR41 article-title: The association between the plasma sugar and lipid profile with the gene expression of the regulatory protein of mTOR (Raptor) in patients with rheumatoid arthritis publication-title: Immunological Investigations doi: 10.1080/08820139.2020.1781160 contributor: fullname: Samimi – volume: 7 issue: 1 year: 2021 ident: CR14 article-title: Inflammaging as a link between autoimmunity and cardiovascular disease: the case of rheumatoid arthritis publication-title: RMD Open doi: 10.1136/rmdopen-2020-001470 contributor: fullname: Santos-Moreno – volume: 379 start-page: 1298 issue: 6639 year: 2023 end-page: 1300 ident: CR43 article-title: The link between obesity and autoimmunity publication-title: Science doi: 10.1126/science.ade0113 contributor: fullname: Matarese – volume: 17 start-page: 270 issue: 5 year: 2021 ident: 1884_CR50 publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-021-00593-3 contributor: fullname: F Atzeni – volume: 10 start-page: 1146353 year: 2023 ident: 1884_CR47 publication-title: Frontiers in Medicine doi: 10.3389/fmed.2023.1146353 contributor: fullname: B Brynedal – volume: 62 start-page: 2594 issue: 7 year: 2022 ident: 1884_CR34 publication-title: Rheumatology doi: 10.1093/rheumatology/keac617 contributor: fullname: L Al-Jaberi – volume: 41 start-page: 863 issue: 5 year: 2021 ident: 1884_CR4 publication-title: Rheumatology international doi: 10.1007/s00296-020-04731-0 contributor: fullname: K Almutairi – volume: 383 start-page: 999 issue: 9921 year: 2014 ident: 1884_CR28 publication-title: Lancet doi: 10.1016/S0140-6736(13)61752-3 contributor: fullname: SS Mahmood – volume: 18 start-page: 398 issue: 7 year: 2022 ident: 1884_CR1 publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-022-00771-x contributor: fullname: U Fearon – volume: 10 start-page: 1938 issue: 8 year: 2022 ident: 1884_CR12 publication-title: Biomedicines doi: 10.3390/biomedicines10081938 contributor: fullname: W Frąk – volume: 5 start-page: R241 year: 2003 ident: 1884_CR36 publication-title: Arthritis Research & Therapy doi: 10.1186/ar783 contributor: fullname: P Ruschpler – volume: 361 start-page: k1036 year: 2018 ident: 1884_CR49 publication-title: The BMJ doi: 10.1136/bmj.k1036 contributor: fullname: BR England – volume: 7 start-page: 19 issue: 1 year: 2020 ident: 1884_CR16 publication-title: Rheumatology and Therapy doi: 10.1007/s40744-019-00189-0 contributor: fullname: DJ DeMizio – volume-title: Seminars in immunology year: 2003 ident: 1884_CR20 contributor: fullname: Z Szekanecz – volume: 129 start-page: S49 issue: 25_suppl_2 year: 2014 ident: 1884_CR27 publication-title: Circulation doi: 10.1161/01.cir.0000437741.48606.98 contributor: fullname: DC Goff Jr – volume: 41 start-page: 265 year: 2022 ident: 1884_CR18 publication-title: Clinical Rheumatology doi: 10.1007/s10067-021-05899-x contributor: fullname: M Pournazari – volume: 38 start-page: 44 issue: 1 year: 1995 ident: 1884_CR26 publication-title: Arthritis & Rheumatism: Official Journal of the American College of Rheumatology doi: 10.1002/art.1780380107 contributor: fullname: M Prevoo – volume: 8 start-page: 689698 year: 2021 ident: 1884_CR2 publication-title: Frontiers in Medicine doi: 10.3389/fmed.2021.689698 contributor: fullname: VC Romão – volume: 379 start-page: 1298 issue: 6639 year: 2023 ident: 1884_CR43 publication-title: Science doi: 10.1126/science.ade0113 contributor: fullname: G Matarese – volume: 10 issue: 10 year: 2015 ident: 1884_CR23 publication-title: PLoS ONE doi: 10.1371/journal.pone.0141394 contributor: fullname: R Altara – volume: 103 start-page: 766 issue: 10 year: 2017 ident: 1884_CR40 publication-title: Heart doi: 10.1136/heartjnl-2015-308953 contributor: fullname: F O'Neill – volume: 702 start-page: 8 year: 2019 ident: 1884_CR7 publication-title: Gene doi: 10.1016/j.gene.2019.03.033 contributor: fullname: J Karami – volume: 12 start-page: 3830 year: 2022 ident: 1884_CR22 publication-title: Frontiers in Pharmacology doi: 10.3389/fphar.2021.765768 contributor: fullname: X Lu – volume: 76 start-page: 17 issue: 1 year: 2017 ident: 1884_CR13 publication-title: Annals of the Rheumatic Diseases doi: 10.1136/annrheumdis-2016-209775 contributor: fullname: R Agca – volume: 17 start-page: 6 year: 2020 ident: 1884_CR3 publication-title: Immunity & Ageing doi: 10.1186/s12979-020-00178-w contributor: fullname: ME Bauer – volume: 67 start-page: 457 issue: 4 year: 2015 ident: 1884_CR42 publication-title: Arthritis Care & Research doi: 10.1002/acr.22483 contributor: fullname: RJ Desai – volume: 19 start-page: 20 issue: 1 year: 2017 ident: 1884_CR32 publication-title: Arthritis Research & Therapy doi: 10.1186/s13075-017-1224-1 contributor: fullname: JM Pandya – volume: 50 start-page: 3866 issue: 12 year: 2004 ident: 1884_CR21 publication-title: Arthritis & Rheumatism doi: 10.1002/art.20615 contributor: fullname: R García-Vicuña – volume: 32 start-page: 534 issue: 3 year: 2016 ident: 1884_CR37 publication-title: Pakistan Journal of Medical Sciences doi: 10.12669/pjms.323.9779 contributor: fullname: AA Wagan – volume: 20 start-page: 511 issue: 7 year: 1967 ident: 1884_CR29 publication-title: Journal of Chronic Diseases doi: 10.1016/0021-9681(67)90082-3 contributor: fullname: J Truett – volume: 344 start-page: 907 issue: 12 year: 2001 ident: 1884_CR19 publication-title: New England Journal of Medicine doi: 10.1056/NEJM200103223441207 contributor: fullname: EH Choy – volume: 26 start-page: 311 issue: 3 year: 2015 ident: 1884_CR35 publication-title: Cytokine & Growth Factor Reviews doi: 10.1016/j.cytogfr.2014.11.009 contributor: fullname: K Van Raemdonck – volume: 24 start-page: 987 issue: 11 year: 2003 ident: 1884_CR30 publication-title: European Heart Journal doi: 10.1016/S0195-668X(03)00114-3 contributor: fullname: RM Conroy – volume: 16 start-page: 361 issue: 7 year: 2020 ident: 1884_CR11 publication-title: Nature Reviews Rheumatology doi: 10.1038/s41584-020-0428-y contributor: fullname: AG Semb – volume: 1 start-page: 598 issue: 7 year: 2021 ident: 1884_CR17 publication-title: Nature Aging doi: 10.1038/s43587-021-00082-y contributor: fullname: N Sayed – volume: 104 start-page: 1041 issue: 8 year: 1999 ident: 1884_CR39 publication-title: The Journal of Clinical Investigation doi: 10.1172/JCI6993 contributor: fullname: F Mach – volume: 7 issue: 1 year: 2021 ident: 1884_CR14 publication-title: RMD Open doi: 10.1136/rmdopen-2020-001470 contributor: fullname: P Santos-Moreno – volume: 50 start-page: 597 issue: 6 year: 2021 ident: 1884_CR41 publication-title: Immunological Investigations doi: 10.1080/08820139.2020.1781160 contributor: fullname: Z Samimi – volume: 20 issue: 4 year: 2021 ident: 1884_CR8 publication-title: Autoimmunity Reviews doi: 10.1016/j.autrev.2021.102776 contributor: fullname: FA Figus – volume: 18 start-page: 591 issue: 10 year: 2022 ident: 1884_CR5 publication-title: Nature Reviews Rheumatology contributor: fullname: A Finckh – volume: 130 start-page: 463 issue: 7 year: 2016 ident: 1884_CR38 publication-title: Clinical Science doi: 10.1042/CS20150666 contributor: fullname: R Altara – volume: 19 start-page: 3037 issue: 16 year: 2015 ident: 1884_CR48 publication-title: European Review for Medical and Pharmacological Sciences contributor: fullname: D Kotrych – volume: 29 start-page: e45 issue: 9 year: 2001 ident: 1884_CR25 publication-title: Nucleic Acids Research doi: 10.1093/nar/29.9.e45 contributor: fullname: MW Pfaffl – volume: 8 start-page: 659 issue: 5 year: 2019 ident: 1884_CR24 publication-title: Journal of Clinical Medicine doi: 10.3390/jcm8050659 contributor: fullname: CF Lin – volume: 170 start-page: Itc1 issue: 1 year: 2019 ident: 1884_CR9 publication-title: Annals of Internal Medicine doi: 10.7326/AITC201901010 contributor: fullname: JA Sparks – volume: 46 start-page: 211 issue: 4 year: 2018 ident: 1884_CR10 publication-title: Medicine doi: 10.1016/j.mpmed.2018.01.008 contributor: fullname: M Gulati – volume: 20 start-page: 1958 issue: 12 year: 2017 ident: 1884_CR46 publication-title: International Journal of Rheumatic Diseases doi: 10.1111/1756-185X.12589 contributor: fullname: HDL Bonfante – volume: 60 start-page: 22 issue: 1 year: 2009 ident: 1884_CR44 publication-title: Arthritis & Rheumatism doi: 10.1002/art.24148 contributor: fullname: RL Rudominer – volume: 37 start-page: 257 issue: 2 year: 2010 ident: 1884_CR31 publication-title: The Journal of Rheumatology doi: 10.3899/jrheum.090769 contributor: fullname: WP Kuan – volume: 361 year: 2018 ident: 1884_CR15 publication-title: BMJ doi: 10.1136/bmj.k1036 contributor: fullname: BR England – volume: 388 start-page: 529 issue: 6 year: 2023 ident: 1884_CR33 publication-title: New England Journal of Medicine doi: 10.1056/NEJMra2103726 contributor: fullname: EM Gravallese – volume: 20 issue: 2 year: 2021 ident: 1884_CR6 publication-title: Autoimmunity Reviews doi: 10.1016/j.autrev.2020.102735 contributor: fullname: A Conforti – volume: 82 start-page: 3 issue: 1 year: 2023 ident: 1884_CR45 publication-title: Annals of the Rheumatic Diseases doi: 10.1136/ard-2022-223356 contributor: fullname: JS Smolen |
SSID | ssj0008983 |
Score | 2.4238603 |
Snippet | Cardiovascular disease (CVD) is the most common cause of mortality in rheumatoid arthritis (RA), and Inflammation has a decisive role in its pathogenesis.... |
SourceID | proquest crossref pubmed springer |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 2374 |
SubjectTerms | Biomedical and Life Sciences Biomedicine Blood pressure Cardiovascular diseases CXCR3 protein Gene expression High density lipoprotein Immunology Inflammation Internal Medicine Low density lipoprotein Pathogenesis Pathology Pharmacology/Toxicology Plasma Plasma levels Rheumatoid arthritis Rheumatology Risk factors |
SummonAdditionalLinks | – databaseName: SpringerLINK - Czech Republic Consortium dbid: AGYKE link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV1LT-MwEB6xRUJ74bU8shRkJG5LEGns2D6WivdDqAKpnCI7dqUKCNUmveyv33GctKDCgavjRzxjz3yjeRjgAJXo0KDqQg4IGVLdoaGikQrZsYqEpUNKqctGvr1LLh7p1YANZnncVbB745GsBPW7XDdE1iGqGLR-haAh-wGLzBX8asFi9_zp-nQqgIX01TfjBEWMlLzOlfl8lo_6aA5kzjlIK71ztgIPTfaODzd5PpqU-ij7N1_M8TtbWoXlGoeSrj84a7Bg83VYuq097b_gpTfo3UiickNGZUEQXdoxmucEm_vxIbaTy9cKuuclcfYsOfEBX-QyH-Ih8wmR1fDeh4hX0h8VzwUZ5aTfJfe-qGuxAY9npw-9i7B-mSHMaCTLUFvqcBZiwQwBkE4s4jLLHd7gVAtu0ELXUdKR2qBM0GizZCxK2NBGGW5ZRzzehFb-ltttIMpSJSOVaYZA49gIlQljWWKYNdzIDg_gT8OfdOwLcKSzUsuOgCkSMK0ImLIA2g0L0_oyFinalLFzIMcygP3pZ7xGzjeicvs2cX1ogqtxLgLY8qyfLle9Eow4JoDDho-zyb_-l9_f674DP91T9j5Upg2t8u_E7iLgKfVefcD_AwJT8ZY priority: 102 providerName: Springer Nature |
Title | CXCL9 and its Receptor CXCR3, an Important Link Between Inflammation and Cardiovascular Risks in RA Patients |
URI | https://link.springer.com/article/10.1007/s10753-023-01884-5 https://www.ncbi.nlm.nih.gov/pubmed/37542661 https://www.proquest.com/docview/2893280639 https://search.proquest.com/docview/2846927778 |
Volume | 46 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3da9swED_WBsZeSvfttQsa7G0Vq2zJkp5KEpK12xpKWCB7MpKlQNjmpLP7__dkKwmlbE8G-UvcSXe_030BfEQlunSoupADSlNuU04NZ4aKc8OU50vOechGvp7ml3P-dSEW8cCtjmGVW5nYCmq3LsMZ-Wc0DLLgBcz0xeaWhq5RwbsaW2gcQC9lPLhpe8Px9Ga2k8VKd4U4sxyljdYyps3E5DmE6hR1FprTSnEqHqqmR3jzka-0VUGTYziK2JEMOmY_hye-egFPr6N3_CX8Hi1G3zUxlSOrpiaICP0GTWqCw7PsDMfJ1Z8WblcNCTYoGXZBWuSqWuLC6JIY29dHD6JUyWxV_6rJqiKzAbnpCrHWr2A-Gf8YXdLYTYGWnOmGWs8DNkL8ViJosblHLOVlwAiSWyUdWtWW5am2DvexRTujFCwXS89KJJRlMnsNh9W68m-BGM-NZqa0AsHBuVOmVM6L3AnvpNOpTODTlpDFpiuaUezLIweyF0j2oiV7IRI43dK6iBuoLvbsTuDD7jYu_eDPMJVf34Vn0LZPpZQqgTcdj3a_azv7IvZI4GzLtP3H_z2Xd_-fywk8C-3mu3CWUzhs_t759whKGtuHA7mQfegNJsPhNFy__Pw27sf1iHfn6eAeTSDe5w |
link.rule.ids | 315,786,790,12083,21416,27955,27956,31752,33777,41114,41556,42183,42625,43343,43838,52144,52267,74100,74657 |
linkProvider | ProQuest |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3rS8MwED98gPpFfFufEfymQbsmTfNJdCibbiJDYd9K0mQw1G7a-v97abMNEf2aPhLuLrnf5V4Ap6hEBwZVF3IgkZTpBqOKhYrySxUmlg0YYy4bufsYt17YfZ_3_YVb4cMqJ2didVCbUebuyC_QMIicFzCSV-MP6rpGOe-qb6ExD4ssipiTc9GfGlw4e12GM4rxrJFS-KQZnzqHQJ2ixkJjOkkY5T8V0y-0-ctTWimguzVY9ciRXNesXoc5m2_AUtf7xjfhrdlvdiRRuSHDsiCIB-0YDWqCw73oHMdJ-70C23lJnAVKbuoQLdLOBygWdQpj9XnzR4wq6Q2L14IMc9K7Jk91GdZiC17ubp-bLep7KdCMhbKk2jKHjBC9ZQhZdGwRSVnhEIJgOhEGbWodxg2pDe5ijVZGxsOYD2yYIaF0KKJtWMhHud0FoixTMlSZ5ggNLk2issRYHhtujTCyIQI4mxAyHdclM9JZcWRH9hTJnlZkT3kABxNap377FOmM2QGcTB-j4Dtvhsrt6Mu9g5Z9QwiRBLBT82g6XdXXF5FHAOcTps1-_vda9v5fyzEst567nbTTfnzYhxXXeL4ObDmAhfLzyx4iPCn1USWD38_M244 |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3dT9swED9tTKr2ghhjWxgDT-KNWm0aO46fEOuoKNCqqqjUt8iOHakapIWE_3_nxG1Voe3V-bLubN_vl_sCOEcjmhs0XaiBRFKme4wqFirKuypMLMsZYy4beTSOb2bsds7nPv6p9GGV6zOxPqjNMnP_yDtIDCLnBYxkJ_dhEZPfg8vVM3UdpJyn1bfTeA8f0Ep2XRsHMd-QL5xJU5IzivHckVL4BBqfRoegnaL1QmKdJIzyXSP1Bnm-8ZrWxmhwAPseRZKrRu2f4J0tDqE18n7yz_DYn_fvJVGFIYuqJIgN7QrJNcHhadTGcTJ8qoF3URHHRsmvJlyLDIscl0iTzlg_3t-JVyXTRfmnJIuCTK_IpCnJWh7BbHD90L-hvq8CzVgoK6otcygJkVyG8EXHFlGVFQ4tCKYTYZBf6zDuSW1wR2tkHBkPY57bMENB6VBEX2CvWBb2GxBlmZKhyjRHmNA1icoSY3lsuDXCyJ4I4GItyHTVlM9It4WSndhTFHtaiz3lAZysZZ36rVSmW8UH8HNzGTeB82yowi5f3T3I8ntCiCSAr42ONp-re_wiCgmgvVba9uX_nsvx_-dyBi1cfun9cHz3HT66HvRNjMsJ7FUvr_YHIpVKn9ZL8C9InN-6 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=CXCL9+and+its+Receptor+CXCR3%2C+an+Important+Link+Between+Inflammation+and+Cardiovascular+Risks+in+RA+Patients&rft.jtitle=Inflammation&rft.au=Shamsi%2C+Afsaneh&rft.au=Roghani%2C+Seyed+Askar&rft.au=Abdan%2C+Zahra&rft.au=Soufivand%2C+Parviz&rft.date=2023-12-01&rft.pub=Springer+Nature+B.V&rft.issn=0360-3997&rft.eissn=1573-2576&rft.volume=46&rft.issue=6&rft.spage=2374&rft.epage=2385&rft_id=info:doi/10.1007%2Fs10753-023-01884-5&rft.externalDBID=HAS_PDF_LINK |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0360-3997&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0360-3997&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0360-3997&client=summon |