Activation of Prostaglandin E Receptor 4 Triggers Secretion of Gut Hormone Peptides GLP-1, GLP-2, and PYY - Coskun, Tamer; O’Farrell, Libbey S.; Syed, Samreen K.; Briere, Daniel A.; Beavers, Lisa S.; DuBois, Susan L.; Michael, Mervyn D.; Franciskovich, Jeffry B.; Barrett, David G.; Efanov, Alexander M. (Endocrinology (Philadelphia), 2013)
Keywords: Agonists; Animals; Biological and medical sciences; Cell activation; Cells, Cultured; Digestive system; Fundamental and applied biological sciences. Psychology; Gastric Inhibitory Polypeptide - blood; Gastrointestinal tract; Gene expression; Glucagon; Glucagon-Like Peptide 1 - blood; Glucagon-Like Peptide 2 - blood; Hormones; Intestine; Intestines - metabolism; L cells; Mice; Peptide YY - blood; Peptides; Plasma levels; Prostaglandin E; Prostaglandin E1; Prostaglandins; Real-Time Polymerase Chain Reaction; Receptors; Receptors, Prostaglandin E, EP4 Subtype - antagonists & inhibitors; Receptors, Prostaglandin E, EP4 Subtype - genetics; Receptors, Prostaglandin E, EP4 Subtype - metabolism; Secretion; siRNA; Thiophenes - pharmacology; Triazoles - pharmacology; Vertebrates: endocrinology; Gastrointestinal hormone; Digestive system; Secretion; Peptide hormone; Gut; Activation; Prostaglandin E; YY peptide; Glucagon like peptide 1; Biological receptor