Design, Synthesis, and Antibacterial Evaluation of Some Novel 3′-(Phenylamino)-1′H-spiro[indoline-3,2′-quinazoline]-2,4′(3′H)-dione Derivatives

A combinatorial synthesis and evaluation of antibacterial activity against clinically isolated resistant strains of Gram-positive and Gram-negative bacteria of 3′-(phenylamino)-1′H-spiro[indoline-3,2′-quinazoline]-2,4′(3′H)-dione derivatives is described.

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Bibliographic Details
Published inSynthetic communications Vol. 44; no. 4; pp. 457 - 467
Main Authors Mohammadi, Ali A., Askari, Saber, Rohi, Hamed, Soorki, Ali Abolhasani
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis Group 16.02.2014
Taylor & Francis
Subjects
Alum
antibacterial activity
Chemistry
Chemistry, Organic
isatoic anhydride
Physical Sciences
quinazoline
Science & Technology
spirooxindole
antibacterial activity
spirooxindole
quinazoline
REUSABLE CATALYST
isatoic anhydride
ONE-POT SYNTHESIS
EFFICIENT SYNTHESIS
Alum
KAL(SO4)CENTER-DOT-12HO
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Summary:A combinatorial synthesis and evaluation of antibacterial activity against clinically isolated resistant strains of Gram-positive and Gram-negative bacteria of 3′-(phenylamino)-1′H-spiro[indoline-3,2′-quinazoline]-2,4′(3′H)-dione derivatives is described.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2013.796992