Exploring the effect of intracellular loop 1 genetic variants in human ABCG2 on transport activity and protein abundance - Sjöstedt, Noora; Timmermans, Ritchie G.M.; Vieraankivi, Marika; Suominen, Laura; Vellonen, Kati-Sisko; Bhattacharya, Madhushree; Auriola, Seppo; Kidron, Heidi (Drug metabolism and pharmacokinetics, 2025)
Keywords: ATP Binding Cassette Transporter, Subfamily G, Member 2 - chemistry; ATP Binding Cassette Transporter, Subfamily G, Member 2 - genetics; ATP Binding Cassette Transporter, Subfamily G, Member 2 - metabolism; Biological Transport - genetics; Breast cancer resistance protein (BCRP); Coupling helix; Estrone - analogs & derivatives; Estrone - metabolism; Genetic Variation - genetics; HEK293 Cells; Humans; Mutation; Neoplasm Proteins - chemistry; Neoplasm Proteins - genetics; Neoplasm Proteins - metabolism; Polymorphism; Polymorphism, Single Nucleotide - genetics; Rosuvastatin Calcium - metabolism; Breast cancer resistance protein (BCRP); Mutation; Coupling helix; Polymorphism