Seed amplification assay results illustrate discrepancy in Parkinson’s disease clinical diagnostic accuracy and error rates - Middleton, John Stephen; Hovren, Hanna Lynn; Kha, Nelson; Medina, Manuel Joseph; MacLeod, Karen Ruth; Concha-Marambio, Luis; Jensen, Kendal Jay (Journal of neurology, 2023)
Keywords: Accuracy; alpha-Synuclein - cerebrospinal fluid; Basal ganglia; Central nervous system diseases; Cerebrospinal fluid; Computed tomography; Diagnosis; Discordance; Dopamine; Dopamine transporter; Humans; Medicine; Medicine & Public Health; Movement disorders; Neurodegenerative diseases; Neurology; Neuroradiology; Neurosciences; Original Communication; Parkinson Disease - cerebrospinal fluid; Parkinson Disease - diagnostic imaging; Parkinson's disease; Parkinsonian Disorders; Single photon emission computed tomography; Statistical analysis; Symbiosis; Synuclein; α-Synuclein; Seed amplification; Synucleinopathy; Parkinson’s disease