Diagnosis of a malignant adrenal mass: the role of urinary steroid metabolite profiling

• Published in: Current opinion in endocrinology, diabetes, and obesity Vol. 24; no. 3; p. 200
• Main Authors: Bancos, Irina, Arlt, Wiebke
• Format: Journal Article
• Language: English
• Published: England 01.06.2017
• Subjects: Adrenal Gland Neoplasms - diagnosis; Adrenal Gland Neoplasms - pathology; Adrenal Gland Neoplasms - urine; Adrenocortical Adenoma - diagnosis; Adrenocortical Adenoma - pathology; Adrenocortical Adenoma - urine; Diagnostic Techniques, Endocrine; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Metabolome; Metabolomics - methods; Sensitivity and Specificity; Steroids - urine; Urinalysis - methods

Adrenal masses are highly prevalent, found in 5% of the population. Differentiation of benign adrenocortical adenoma from adrenocortical carcinoma is currently hampered by the poor specificity and limited evidence base of imaging tests. This review summarizes the results of studies published to date...