Increased risk of biochemical and local failure in patients with distended rectum on the planning CT for prostate cancer radiotherapy

• Published in: International journal of radiation oncology, biology, physics Vol. 62; no. 4; pp. 965 - 973
• Main Authors: de Crevoisier, Renaud, Tucker, Susan L., Dong, Lei, Mohan, Radhe, Cheung, Rex, Cox, James D., Kuban, Deborah A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.07.2005
• Subjects: Aged; BIOPSY; CARCINOMAS; COMPUTERIZED TOMOGRAPHY; Dilatation, Pathologic - complications; Dilatation, Pathologic - diagnostic imaging; Dilatation, Pathologic - pathology; FAILURES; Gases; Gastrointestinal Hemorrhage - etiology; HEALTH HAZARDS; Humans; HYPOTHESIS; IRRADIATION; Male; Middle Aged; Neoplasm, Residual - pathology; Organ motion; PATIENTS; PLANNING; PROSTATE; Prostate - pathology; Prostate cancer; Prostate-Specific Antigen - blood; Prostatic Neoplasms - blood; Prostatic Neoplasms - diagnostic imaging; Prostatic Neoplasms - radiotherapy; RADIATION DOSES; Radiation Injuries - complications; RADIOLOGY AND NUCLEAR MEDICINE; RADIOTHERAPY; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Conformal; Rectal distension; RECTUM; Rectum - diagnostic imaging; Rectum - pathology; Rectum - radiation effects; Retrospective Studies; Risk factor; SIMULATION; Statistics as Topic; TEXAS; Tomography, X-Ray Computed; TOXICITY; Treatment Failure; Rectal distension; Organ motion; Radiotherapy; Prostate cancer; Risk factor

Purpose: To retrospectively test the hypothesis that rectal distension on the planning computed tomography (CT) scan is associated with an increased risk of biochemical and local failure among patients irradiated for prostate carcinoma when a daily repositioning technique based on direct prostate-or...